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dup 87 /W put dup 88 /X put dup 89 /Y put dup 90 /Z put dup 91 /bracketleft put dup 92 /backslash put dup 93 /bracketright put dup 94 /asciicircum put dup 97 /a put dup 98 /b put dup 99 /c put dup 100 /d put dup 101 /e put dup 102 /f put dup 103 /g put dup 104 /h put dup 105 /i put dup 106 /j put dup 107 /k put dup 108 /l put dup 109 /m put dup 110 /n put dup 111 /o put dup 112 /p put dup 113 /q put dup 114 /r put dup 115 /s put dup 116 /t put dup 117 /u put dup 118 /v put dup 119 /w put dup 120 /x put dup 121 /y put dup 122 /z put dup 123 /braceleft put dup 124 /bar put dup 125 /braceright put dup 126 /asciitilde put readonly def currentdict end currentfile eexec M#1H5 J6o \&rtS(#v\0\޹V7Fe༙OYx5-cY9^%Y6 (efIOldN"wȰ;)UƽoFg/rvV$JS8_oc@  o9-eGJp}[Do]mN=4*{ܯq=eU^t6¤/{zM4aܪ Q:д'B-r^ܦ 6y?rRnu S\U{Oλrs(Βƚ #d 29%s'ƈT 1F8&\0Xd&&Zug'VPd]:>u=Q,?#(CV4 '..׶|ӱ5 h sȀg)fɘ`UXK^>] q\l#5pE"JO }rquáQBr/E7 QW5\GSlu{7ZH(PSf/O;̟w{ɴ}-K hA8!b!U>`#u?Vlnǝ19V+mg'Q mA}S Y$í8n uJ ڒx3>[x0Z] 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[()]TJ /F7 1 Tf (g)Tj 1.1905 0 Td (L)Tj ET Q q 1 j 1 J 0 w 7.4999 0 0 6.6659 302.1165 646.8661 cm BT /F7 1 Tf 1 TL -0.0053 Tc 0 0 Td (-1)Tj ET Q q 1 j 1 J 0 w 10 0 0 10 310.507 642.3874 cm BT /F7 1 Tf 1 TL -0.004 Tc 0 0 Td (\(0.2%)Tj 2.4944 0 Td (DMSO\).)Tj 3.634 0 Td (A)Tj 0.9071 0 Td (final)Tj 2.0012 0 Td (well)Tj 1.8199 0 Td (concentration)Tj 5.8166 0 Td (of)Tj 1.0148 0 Td (100)Tj /F15 1 Tf 1.6498 0 Td [()]TJ /F7 1 Tf (g)Tj 1.1905 0 Td (L)Tj ET Q q 1 j 1 J 0 w 7.4999 0 0 6.6659 521.1779 646.8661 cm BT /F7 1 Tf 1 TL -0.0053 Tc 0 0 Td (-1)Tj ET Q q 1 j 1 J 0 w 10 0 0 10 529.5685 642.3874 cm BT /F7 1 Tf 1 TL -0.004 Tc 0 0 Td (\(0.1%)Tj -32.9553 -1.2982 Td (DMSO\))Tj 3.4129 0 Td (for)Tj 1.3833 0 Td (each)Tj 2.0296 0 Td (pharmaceutical)Tj 6.3665 0 Td (was)Tj 1.7008 0 Td (used.)Tj 2.2847 0 Td (Pharmaceuticals)Tj 6.7691 0 Td (that)Tj 1.7801 0 Td (carried)Tj 3.0388 0 Td (a)Tj 0.6519 0 Td (salt)Tj 1.5591 0 Td (weight)Tj 2.8855 0 Td (were)Tj -33.8623 -1.2983 Td (accounted)Tj 4.3313 0 Td 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Td (116.0)Tj /F15 1 Tf 2.347 0 Td [()]TJ /F7 1 Tf 0.788 0 Td (21.7)Tj 1.8709 0 Td (g\))Tj 1.0261 0 Td (and)Tj 1.7292 0 Td (liver)Tj 1.9842 0 Td (dissociation)Tj 4.9889 0 Td (procedures)Tj 4.6772 0 Td (are)Tj 1.4456 0 Td (described)Tj 4.0536 0 Td (previously)Tj 4.3483 0 Td ([)Tj 0.83 0.64 0.02 0 k (10)Tj 0 g (].)Tj 2.0806 0 Td (Individual)Tj 4.3597 0 Td (liv-)Tj -35.6993 -1.2982 Td (ers)Tj 1.3719 0 Td (\(wet)Tj 1.9672 0 Td (weight:)Tj 3.1125 0 Td (1.43)Tj /F15 1 Tf 1.8708 0 Td [()]TJ /F7 1 Tf 0.7937 0 Td (0.34)Tj 1.8709 0 Td (g\))Tj 1.0261 0 Td (produced)Tj 4.0422 0 Td (a)Tj 0.6576 0 Td (sufficient)Tj 3.9118 0 Td (cellular)Tj 3.1351 0 Td (yield)Tj 2.143 0 Td (to)Tj 1.0261 0 Td (use)Tj 1.5307 0 Td (single)Tj 2.5285 0 Td (fish)Tj 1.6668 0 Td (replicates,)Tj -0.01 Tc -32.6549 -1.2983 Td (thus)Tj 1.9048 0 Td (each)Tj 2.0013 0 Td (fish)Tj 1.6384 0 Td (was)Tj 1.6781 0 Td (used)Tj 2.0352 0 Td (as)Tj 0.9978 0 Td (an)Tj 1.1906 0 Td (individual)Tj 4.2236 0 Td (experiment.)Tj 4.9379 0 Td (Cell)Tj 1.7688 0 Td (viability)Tj 3.3619 0 Td (after)Tj 2.0012 0 Td (isolation)Tj 3.6 0 Td (was)Tj 1.6781 0 Td (determined)Tj -33.0177 -1.3039 Td (by)Tj 1.1678 0 Td (a)Tj 0.6463 0 Td (trypan)Tj 2.812 0 Td (blue)Tj 1.8992 0 Td (exclusion)Tj 3.9344 0 Td (test)Tj 1.5761 0 Td (\(0.2%)Tj 2.4661 0 Td (final)Tj 1.9729 0 Td (volume;)Tj 3.3846 0 Td (L-15)Tj 2.0352 0 Td (medium\))Tj 3.9061 0 Td (and)Tj 1.7121 0 Td (cell)Tj 1.5307 0 Td (suspensions)Tj 4.938 0 Td (with)Tj 1.9729 0 Td (a)Tj -35.9544 -1.2983 Td (viability)Tj 3.3618 0 Td (of)Tj /F14 1 Tf 0 Tc 1.0035 0 Td ()Tj /F7 1 Tf -0.01 Tc 0.9921 0 Td (85%)Tj 1.9105 0 Td (were)Tj 2.0977 0 Td (used)Tj 2.0352 0 Td (for)Tj 1.3663 0 Td (spheroid)Tj 3.6737 0 Td (culture.)Tj 3.2201 0 Td (Penicillin-Streptomycin)Tj 9.6321 0 Td (\(5,000)Tj 2.6532 0 Td (U)Tj 0.9524 0 Td (mL)Tj ET Q q 1 j 1 J 0 w 7.4999 0 0 6.6659 542.4377 499.3511 cm BT /F7 1 Tf 1 TL -0.0133 Tc 0 0 Td (-1)Tj ET Q q 1 j 1 J 0 w 10 0 0 10 548.5039 494.9291 cm BT /F7 1 Tf 1 TL -0.01 Tc 0 0 Td (\))Tj 0.5555 0 Td (and)Tj -35.4044 -1.2982 Td (amphotericin)Tj 5.5502 0 Td (B)Tj 0.7937 0 Td (\(250)Tj /F15 1 Tf 1.9673 0 Td [()]TJ /F7 1 Tf (g)Tj 1.1792 0 Td (mL)Tj ET Q q 1 j 1 J 0 w 7.4999 0 0 6.6659 308.3527 486.3685 cm BT /F7 1 Tf 1 TL -0.0133 Tc 0 0 Td (-1)Tj ET Q q 1 j 1 J 0 w 10 0 0 10 314.4188 481.9464 cm BT /F7 1 Tf 1 TL -0.01 Tc 0 0 Td (\))Tj 0.5555 0 Td (were)Tj 2.0977 0 Td (added)Tj 2.6305 0 Td (to)Tj 1.0148 0 Td (the)Tj 1.4513 0 Td (culture)Tj 2.9934 0 Td (medium)Tj 3.5716 0 Td (\(1%)Tj 1.7745 0 Td (v:v\))Tj 1.6724 0 Td (in)Tj 1.0205 0 Td (addition)Tj 3.5489 0 Td (to)Tj 1.0148 0 Td (foetal)Tj -34.7864 -1.3039 Td (bovine)Tj 2.8913 0 Td (serum)Tj 2.6929 0 Td (\(FBS;)Tj 2.3357 0 Td (10%)Tj 1.9106 0 Td (v:v\).)Tj 1.8934 0 Td (Cell)Tj 1.7745 0 Td (suspension)Tj 4.5807 0 Td (aliquots)Tj 3.3222 0 Td (\(1)Tj 1.0262 0 Td (X)Tj 0.8674 0 Td (10)Tj ET Q q 1 j 1 J 0 w 7.4999 0 0 6.6659 442.3181 473.3858 cm BT /F7 1 Tf 1 TL -0.0133 Tc 0 0 Td (6)Tj ET Q q 1 j 1 J 0 w 10 0 0 10 448.044 468.907 cm BT /F7 1 Tf 1 TL -0.01 Tc 0 0 Td (cells)Tj 1.8878 0 Td (mL)Tj ET Q q 1 j 1 J 0 w 7.4999 0 0 6.6659 480.4157 473.3858 cm BT /F7 1 Tf 1 TL -0.0133 Tc 0 0 Td (-1)Tj ET Q q 1 j 1 J 0 w 10 0 0 10 486.4251 468.907 cm BT /F7 1 Tf 1 TL -0.01 Tc 0 0 Td (;)Tj 0.4422 0 Td (3)Tj 0.6916 0 Td (mL)Tj 1.5647 0 Td (volume\))Tj 3.4979 0 Td (were)Tj -34.8374 -1.2982 Td (transferred)Tj 4.5694 0 Td (to)Tj 1.0148 0 Td (wells)Tj 2.1543 0 Td (of)Tj 0.9978 0 Td (Poly\(2-hydroxyethyl)Tj 8.2998 0 Td (methacrylate\))Tj 5.6409 0 Td (\(pHEMA\)-coated)Tj 7.2112 0 Td (six-well)Tj 3.2145 0 Td (micro-)Tj -33.1027 -1.2983 Td (plates)Tj 2.4604 0 Td (\(Falcon,)Tj 3.4299 0 Td (VWR,)Tj 2.6986 0 Td (UK\))Tj 1.9559 0 Td (and)Tj 1.7121 0 Td (placed)Tj 2.7553 0 Td (on)Tj 1.2642 0 Td (an)Tj 1.1905 0 Td (orbital)Tj 2.8063 0 Td (shaking)Tj 3.2769 0 Td (platform)Tj 3.6566 0 Td (\(Innova)Tj 3.3505 0 Td (2000,)Tj 2.3187 0 Td (Eppendorf,)Tj -32.8759 -1.2982 Td (UK\),)Tj 2.1713 0 Td (set)Tj 1.2812 0 Td (at)Tj 0.9411 0 Td (a)Tj 0.652 0 Td (constant)Tj 3.5886 0 Td (rotation)Tj 3.4016 0 Td (speed)Tj 2.4434 0 Td (of)Tj 1.0035 0 Td (70)Tj 1.1622 0 Td (RPM.)Tj 2.4945 0 Td (Plates)Tj 2.5058 0 Td (were)Tj 2.0976 0 Td (maintained)Tj 4.7282 0 Td (at)Tj 0.941 0 Td (15)Tj /F15 1 Tf 1.1565 0 Td [()]TJ /F7 1 Tf 0.788 0 Td (1C)Tj 1.7291 0 Td (in)Tj 1.0262 0 Td (a)Tj 0.6463 0 Td (tem-)Tj -34.7581 -1.304 Td (perature)Tj 3.5376 0 Td (controlled)Tj 4.2576 0 Td (laboratory.)Tj 4.5127 0 Td (Culture)Tj 3.2372 0 Td (media)Tj 2.6589 0 Td (was)Tj 1.6837 0 Td (replaced)Tj 3.5376 0 Td (every)Tj 2.3188 0 Td (two)Tj 1.6894 0 Td (days)Tj 1.9785 0 Td (until)Tj 2.0749 0 Td (spheroids)Tj -31.4869 -1.2982 Td (reached)Tj 3.3108 0 Td (maturity)Tj 3.6397 0 Td (\(8)Tj 1.0261 0 Td (days\).)Tj 2.5228 0 Td (A)Tj 0.9014 0 Td (more)Tj 2.3188 0 Td (detailed)Tj 3.3165 0 Td (protocol)Tj 3.5489 0 Td (for)Tj 1.372 0 Td (cell)Tj 1.5364 0 Td (isolation)Tj 3.5999 0 Td (and)Tj 1.7121 0 Td (spheroid)Tj 3.6736 0 Td (formation)Tj -32.479 -1.2983 Td (is)Tj 0.8334 0 Td (described)Tj 4.0024 0 Td (previously)Tj 4.286 0 Td ([)Tj 0.83 0.64 0.02 0 k (10)Tj 0 g (].)Tj ET Q q 1 j 1 J 0 w 11.9999 0 0 11.9999 200.0125 364.4787 cm BT /F0 1 Tf 1 TL -0.0033 Tc 0 0 Td (Preparation)Tj 5.3244 0 Td (of)Tj 1.0441 0 Td (spheroids)Tj 4.4977 0 Td (for)Tj 1.3795 0 Td (exposures)Tj ET Q q 1 j 1 J 0 w 10 0 0 10 200.0125 347.4708 cm BT /F7 1 Tf 1 TL -0.004 Tc 0 0 Td (Spheroids)Tj 4.1952 0 Td (\(8)Tj 1.0375 0 Td (d\))Tj 1.0885 0 Td (were)Tj 2.1203 0 Td (pooled)Tj 2.948 0 Td (\(for)Tj 1.7291 0 Td (each)Tj 2.0296 0 Td (individual)Tj 4.286 0 Td (fish)Tj 1.6667 0 Td (liver\))Tj 2.3187 0 Td (from)Tj 2.2054 0 Td (6-well)Tj 2.6475 0 Td (micro)Tj 2.6079 0 Td (plates,)Tj 2.7269 0 Td (into)Tj 1.8425 0 Td (a)Tj -35.4498 -1.2982 Td (pHEMA-coated)Tj 6.616 0 Td (50)Tj 1.1678 0 Td (mL)Tj 1.5818 0 Td (centrifuge)Tj 4.2519 0 Td (tube)Tj 1.9786 0 Td (and)Tj 1.7291 0 Td (washed)Tj 3.1804 0 Td (three)Tj 2.2621 0 Td (times)Tj 2.3924 0 Td (with)Tj 1.9956 0 Td (10)Tj 1.1735 0 Td (mL)Tj 1.5761 0 Td (L-15)Tj 2.0579 0 Td (medium)Tj 3.6057 0 Td (\(no)Tj -35.5689 -1.3039 Td (serum)Tj 2.7212 0 Td (or)Tj 1.0998 0 Td (anti-biotic)Tj 4.388 0 Td (mixture;)Tj 3.617 0 Td (spheroids)Tj 4.0819 0 Td (were)Tj 2.126 0 Td (allowed)Tj 3.2881 0 Td (to)Tj 1.0262 0 Td (sediment)Tj 3.8891 0 Td (without)Tj 3.3278 0 Td (centrifugation)Tj 5.8904 0 Td (prior)Tj -35.4555 -1.2983 Td (to)Tj 1.0261 0 Td (each)Tj 2.0239 0 Td (washing)Tj 3.5093 0 Td (step\).)Tj 2.3867 0 Td (As)Tj 1.2643 0 Td (spheroids)Tj 4.0818 0 Td (are)Tj 1.4514 0 Td (too)Tj 1.5307 0 Td (large)Tj 2.16 0 Td (to)Tj 1.0261 0 Td (be)Tj 1.1509 0 Td (counted)Tj 3.4752 0 Td (on)Tj 1.2756 0 Td (a)Tj 0.6576 0 Td (haemocytometer,)Tj 7.1716 0 Td (4)Tj 0.6973 0 Td (x)Tj 0.686 0 Td (5)Tj /F15 1 Tf 0.6973 0 Td [()]TJ /F7 1 Tf (L)Tj -36.2718 -1.2983 Td (drops)Tj 2.5058 0 Td (of)Tj 1.0148 0 Td (spheroid)Tj 3.719 0 Td (suspension)Tj 4.6431 0 Td (were)Tj 2.1203 0 Td (transferred)Tj 4.6431 0 Td (to)Tj 1.0205 0 Td (a)Tj 0.6576 0 Td (glass)Tj 2.0863 0 Td (microscope)Tj 4.8416 0 Td (slide)Tj 2.0466 0 Td (and)Tj 1.7291 0 Td (spheroids)Tj 4.0819 0 Td (were)Tj -35.1097 -1.3039 Td (counted)Tj 3.4752 0 Td (at)Tj 0.9524 0 Td (x4)Tj 1.1622 0 Td (magnification)Tj 5.7883 0 Td (under)Tj 2.6192 0 Td (an)Tj 1.2019 0 Td (inverted)Tj 3.532 0 Td (light)Tj 2.0239 0 Td (microscope)Tj 4.8415 0 Td (\(Olympus)Tj ET Q q 1 j 1 J 0 w 7.4999 0 0 6.6659 496.1196 286.9228 cm BT /F16 1 Tf 1 TL -0.0053 Tc 0 0 Td (1)Tj ET Q q 1 j 1 J 0 w 10 0 0 10 505.8141 282.444 cm BT /F7 1 Tf 1 TL -0.004 Tc 0 0 Td (CK40-SLP\).)Tj -30.5799 -1.2982 Td (Spheroid)Tj 3.8381 0 Td (suspensions)Tj 5.0003 0 Td (were)Tj 2.1259 0 Td (transferred)Tj 4.6375 0 Td (to)Tj 1.0261 0 Td (a)Tj 0.652 0 Td (sterile)Tj 2.6135 0 Td (reagent)Tj 3.1805 0 Td (reservoir,)Tj 3.9968 0 Td (agitated)Tj 3.3675 0 Td (with)Tj 2.0012 0 Td (a)Tj 0.6519 0 Td (multi-)Tj -33.0913 -1.2983 Td (channel)Tj 3.3732 0 Td (pipette)Tj 2.965 0 Td (to)Tj 1.0261 0 Td (maintain)Tj 3.8325 0 Td (a)Tj 0.6576 0 Td (homogenous)Tj 5.4141 0 Td (suspension)Tj 4.6432 0 Td (and)Tj 1.7291 0 Td (transferred)Tj 4.6374 0 Td (to)Tj 1.0262 0 Td (96-well)Tj 3.1236 0 Td (pHEMA-)Tj -32.428 -1.3039 Td (coated)Tj 2.8346 0 Td (micro)Tj 2.6079 0 Td (plates)Tj 2.5001 0 Td (\(Iwaki,)Tj 3.0047 0 Td (Sterilin,)Tj 3.3449 0 Td (UK\))Tj 1.9672 0 Td (at)Tj 0.9524 0 Td (a)Tj 0.6577 0 Td (seeding)Tj 3.2371 0 Td (density)Tj 3.1011 0 Td (of)Tj 1.0148 0 Td (100)Tj 1.6441 0 Td (spheroids)Tj 4.0818 0 Td (well)Tj ET Q q 1 j 1 J 0 w 7.4999 0 0 6.6659 525.5433 247.9181 cm BT /F7 1 Tf 1 TL -0.0053 Tc 0 0 Td (-1)Tj ET Q q 1 j 1 J 0 w 10 0 0 10 533.8771 243.4393 cm BT /F7 1 Tf 1 TL -0.004 Tc 0 0 Td (\(in)Tj 1.3776 0 Td (75)Tj /F15 1 Tf 1.1735 0 Td [()]TJ /F7 1 Tf (L)Tj -35.9373 -1.2982 Td (L-15)Tj 2.0579 0 Td (medium;)Tj 3.8325 0 Td (pH)Tj 1.5023 0 Td (7.4\).)Tj 1.9616 0 Td (Morphological)Tj 6.1341 0 Td (integrity)Tj 3.617 0 Td (of)Tj 1.0148 0 Td (spheroids)Tj 4.0819 0 Td (was)Tj 1.7007 0 Td (assessed)Tj 3.4696 0 Td (and)Tj 1.7291 0 Td (disaggregated)Tj -31.1015 -1.2983 Td (or)Tj 1.0942 0 Td (fused)Tj 2.3527 0 Td (spheroids)Tj 4.0819 0 Td (removed)Tj 3.7474 0 Td (as)Tj 1.0147 0 Td (a)Tj 0.652 0 Td (quality)Tj 2.9594 0 Td (control)Tj 3.1181 0 Td (check.)Tj ET Q q 1 j 1 J 0 w 11.9999 0 0 11.9999 200.0125 190.9984 cm BT /F0 1 Tf 1 TL -0.0033 Tc 0 0 Td (Tetrazolium)Tj 5.3858 0 Td (salt)Tj 1.7575 0 Td (reduction)Tj 4.2804 0 Td (\(WST-1\))Tj 3.9732 0 Td (viability)Tj 3.4489 0 Td (assay)Tj ET Q q 1 j 1 J 0 w 10 0 0 10 200.0125 173.9905 cm BT /F7 1 Tf 1 TL -0.004 Tc 0 0 Td (Spheroid)Tj 3.838 0 Td (viability)Tj 3.4129 0 Td (was)Tj 1.7008 0 Td (determined)Tj 4.8529 0 Td (prior)Tj 2.2507 0 Td (to)Tj 1.0261 0 Td (substrate)Tj 3.8041 0 Td (depletion)Tj 3.9798 0 Td (experiments)Tj 5.1364 0 Td (by)Tj 1.1792 0 Td (a)Tj 0.6576 0 Td (tetrazolium)Tj -31.8385 -1.2982 Td (salt)Tj 1.559 0 Td (reduction)Tj 4.1159 0 Td (method)Tj 3.3222 0 Td (\(WST-1)Tj 3.4412 0 Td (reagent,)Tj 3.4072 0 Td (Roche)Tj 2.7213 0 Td (Scientific,)Tj 4.1272 0 Td 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667.8893 m 283.661 667.8893 l 283.661 668.3893 l 390.8925 668.3893 l f* 478.0032 680.8893 m 478.0032 667.8893 l 477.5031 668.3893 l 477.5031 680.8893 l f* 478.0032 667.8893 m 391.3926 667.8893 l 391.3926 668.3893 l 477.5031 668.3893 l f* 124.5915 667.8893 m 124.5915 642.8894 l 124.0914 643.3894 l 124.0914 667.8893 l f* 124.5915 642.8894 m 36 642.8894 l 36 643.3894 l 124.0914 643.3894 l f* 208.1126 667.8893 m 208.1126 655.3894 l 207.6126 655.8894 l 207.6126 667.8893 l f* 208.1126 655.3894 m 124.5915 655.3894 l 124.5915 655.8894 l 207.6126 655.8894 l f* 283.661 667.8893 m 283.661 642.8894 l 283.161 643.3894 l 283.161 667.8893 l f* 283.661 642.8894 m 208.1126 642.8894 l 208.1126 643.3894 l 283.161 643.3894 l f* 391.3926 667.8893 m 391.3926 642.8894 l 390.8925 643.3894 l 390.8925 667.8893 l f* 391.3926 642.8894 m 283.661 642.8894 l 283.661 643.3894 l 390.8925 643.3894 l f* 478.0032 667.8893 m 478.0032 642.8894 l 477.5031 643.3894 l 477.5031 667.8893 l f* 478.0032 642.8894 m 391.3926 642.8894 l 391.3926 643.3894 l 477.5031 643.3894 l f* 575.9994 642.8894 m 478.0032 642.8894 l 478.0032 643.3894 l 575.9994 643.3894 l f* 208.1126 655.3894 m 208.1126 642.8894 l 207.6126 643.3894 l 207.6126 655.3894 l f* 208.1126 642.8894 m 124.5915 642.8894 l 124.5915 643.3894 l 207.6126 643.3894 l f* 124.5915 642.8894 m 124.5915 630.3895 l 124.0914 630.8895 l 124.0914 642.8894 l f* 124.5915 630.3895 m 36 630.3895 l 36 630.8895 l 124.0914 630.8895 l f* 208.1126 642.8894 m 208.1126 630.3895 l 207.6126 630.8895 l 207.6126 642.8894 l f* 208.1126 630.3895 m 124.5915 630.3895 l 124.5915 630.8895 l 207.6126 630.8895 l f* 283.661 642.8894 m 283.661 630.3895 l 283.161 630.8895 l 283.161 642.8894 l f* 283.661 630.3895 m 208.1126 630.3895 l 208.1126 630.8895 l 283.161 630.8895 l f* 391.3926 642.8894 m 391.3926 630.3895 l 390.8925 630.8895 l 390.8925 642.8894 l f* 391.3926 630.3895 m 283.661 630.3895 l 283.661 630.8895 l 390.8925 630.8895 l f* 478.0032 642.8894 m 478.0032 630.3895 l 477.5031 630.8895 l 477.5031 642.8894 l f* 478.0032 630.3895 m 391.3926 630.3895 l 391.3926 630.8895 l 477.5031 630.8895 l f* 575.9994 630.3895 m 478.0032 630.3895 l 478.0032 630.8895 l 575.9994 630.8895 l f* 124.5915 630.3895 m 124.5915 605.3896 l 124.0914 605.8896 l 124.0914 630.3895 l f* 124.5915 605.3896 m 36 605.3896 l 36 605.8896 l 124.0914 605.8896 l f* 208.1126 630.3895 m 208.1126 617.8895 l 207.6126 618.3896 l 207.6126 630.3895 l f* 208.1126 617.8895 m 124.5915 617.8895 l 124.5915 618.3896 l 207.6126 618.3896 l f* 283.661 630.3895 m 283.661 605.3896 l 283.161 605.8896 l 283.161 630.3895 l f* 283.661 605.3896 m 208.1126 605.3896 l 208.1126 605.8896 l 283.161 605.8896 l f* 391.3926 630.3895 m 391.3926 605.3896 l 390.8925 605.8896 l 390.8925 630.3895 l f* 391.3926 605.3896 m 283.661 605.3896 l 283.661 605.8896 l 390.8925 605.8896 l f* 478.0032 630.3895 m 478.0032 605.3896 l 477.5031 605.8896 l 477.5031 630.3895 l f* 478.0032 605.3896 m 391.3926 605.3896 l 391.3926 605.8896 l 477.5031 605.8896 l f* 575.9994 605.3896 m 478.0032 605.3896 l 478.0032 605.8896 l 575.9994 605.8896 l f* 208.1126 617.8895 m 208.1126 605.3896 l 207.6126 605.8896 l 207.6126 617.8895 l f* 208.1126 605.3896 m 124.5915 605.3896 l 124.5915 605.8896 l 207.6126 605.8896 l f* 124.5915 605.3896 m 124.5915 592.8897 l 124.0914 593.3897 l 124.0914 605.3896 l f* 124.5915 592.8897 m 36 592.8897 l 36 593.3897 l 124.0914 593.3897 l f* 208.1126 605.3896 m 208.1126 580.3897 l 207.6126 580.8898 l 207.6126 605.3896 l f* 208.1126 580.3897 m 124.5915 580.3897 l 124.5915 580.8898 l 207.6126 580.8898 l f* 283.661 605.3896 m 283.661 580.3897 l 283.161 580.8898 l 283.161 605.3896 l f* 283.661 580.3897 m 208.1126 580.3897 l 208.1126 580.8898 l 283.161 580.8898 l f* 391.3926 605.3896 m 391.3926 580.3897 l 390.8925 580.8898 l 390.8925 605.3896 l f* 391.3926 580.3897 m 283.661 580.3897 l 283.661 580.8898 l 390.8925 580.8898 l f* 478.0032 605.3896 m 478.0032 580.3897 l 477.5031 580.8898 l 477.5031 605.3896 l f* 478.0032 580.3897 m 391.3926 580.3897 l 391.3926 580.8898 l 477.5031 580.8898 l f* 575.9994 580.3897 m 478.0032 580.3897 l 478.0032 580.8898 l 575.9994 580.8898 l f* 124.5915 592.8897 m 124.5915 580.3897 l 124.0914 580.8898 l 124.0914 592.8897 l f* 124.5915 580.3897 m 36 580.3897 l 36 580.8898 l 124.0914 580.8898 l f* 124.5915 580.3897 m 124.5915 567.8898 l 124.0914 568.3898 l 124.0914 580.3897 l f* 124.5915 567.8898 m 36 567.8898 l 36 568.3898 l 124.0914 568.3898 l f* 208.1126 580.3897 m 208.1126 567.8898 l 207.6126 568.3898 l 207.6126 580.3897 l f* 208.1126 567.8898 m 124.5915 567.8898 l 124.5915 568.3898 l 207.6126 568.3898 l f* 283.661 580.3897 m 283.661 555.3899 l 283.161 555.8899 l 283.161 580.3897 l f* 283.661 555.3899 m 208.1126 555.3899 l 208.1126 555.8899 l 283.161 555.8899 l f* 391.3926 580.3897 m 391.3926 555.3899 l 390.8925 555.8899 l 390.8925 580.3897 l f* 391.3926 555.3899 m 283.661 555.3899 l 283.661 555.8899 l 390.8925 555.8899 l f* 478.0032 580.3897 m 478.0032 555.3899 l 477.5031 555.8899 l 477.5031 580.3897 l f* 478.0032 555.3899 m 391.3926 555.3899 l 391.3926 555.8899 l 477.5031 555.8899 l f* 575.9994 555.3899 m 478.0032 555.3899 l 478.0032 555.8899 l 575.9994 555.8899 l f* 124.5915 567.8898 m 124.5915 555.3899 l 124.0914 555.8899 l 124.0914 567.8898 l f* 124.5915 555.3899 m 36 555.3899 l 36 555.8899 l 124.0914 555.8899 l f* 208.1126 567.8898 m 208.1126 555.3899 l 207.6126 555.8899 l 207.6126 567.8898 l f* 208.1126 555.3899 m 124.5915 555.3899 l 124.5915 555.8899 l 207.6126 555.8899 l f* 124.5915 555.3899 m 124.5915 542.8899 l 124.0914 543.39 l 124.0914 555.3899 l f* 124.5915 542.8899 m 36 542.8899 l 36 543.39 l 124.0914 543.39 l f* 208.1126 555.3899 m 208.1126 542.8899 l 207.6126 543.39 l 207.6126 555.3899 l f* 208.1126 542.8899 m 124.5915 542.8899 l 124.5915 543.39 l 207.6126 543.39 l f* 283.661 555.3899 m 283.661 542.8899 l 283.161 543.39 l 283.161 555.3899 l f* 283.661 542.8899 m 208.1126 542.8899 l 208.1126 543.39 l 283.161 543.39 l f* 391.3926 555.3899 m 391.3926 542.8899 l 390.8925 543.39 l 390.8925 555.3899 l f* 391.3926 542.8899 m 283.661 542.8899 l 283.661 543.39 l 390.8925 543.39 l f* 478.0032 555.3899 m 478.0032 542.8899 l 477.5031 543.39 l 477.5031 555.3899 l f* 478.0032 542.8899 m 391.3926 542.8899 l 391.3926 543.39 l 477.5031 543.39 l f* 575.9994 542.8899 m 478.0032 542.8899 l 478.0032 543.39 l 575.9994 543.39 l f* 124.5915 542.8899 m 124.5915 517.89 l 124.0914 518.3901 l 124.0914 542.8899 l f* 124.5915 517.89 m 36 517.89 l 36 518.3901 l 124.0914 518.3901 l f* 208.1126 542.8899 m 208.1126 530.39 l 207.6126 530.89 l 207.6126 542.8899 l f* 208.1126 530.39 m 124.5915 530.39 l 124.5915 530.89 l 207.6126 530.89 l f* 283.661 542.8899 m 283.661 517.89 l 283.161 518.3901 l 283.161 542.8899 l f* 283.661 517.89 m 208.1126 517.89 l 208.1126 518.3901 l 283.161 518.3901 l f* 391.3926 542.8899 m 391.3926 517.89 l 390.8925 518.3901 l 390.8925 542.8899 l f* 391.3926 517.89 m 283.661 517.89 l 283.661 518.3901 l 390.8925 518.3901 l f* 478.0032 542.8899 m 478.0032 517.89 l 477.5031 518.3901 l 477.5031 542.8899 l f* 478.0032 517.89 m 391.3926 517.89 l 391.3926 518.3901 l 477.5031 518.3901 l f* 575.9994 517.89 m 478.0032 517.89 l 478.0032 518.3901 l 575.9994 518.3901 l f* 208.1126 530.39 m 208.1126 517.89 l 207.6126 518.3901 l 207.6126 530.39 l f* 208.1126 517.89 m 124.5915 517.89 l 124.5915 518.3901 l 207.6126 518.3901 l f* 0 g 7.9999 0 0 7.9999 36 708.7181 cm BT /F3 1 Tf 1 TL -0.005 Tc 0 0 Td (Table)Tj 2.7992 0 Td (1.)Tj 1.2614 0 Td (Pharmace)Tj 4.7056 0 Td (uticals)Tj 3.3449 0 Td (used)Tj 2.5228 0 Td (in)Tj 1.1055 0 Td (substrate)Tj 4.6489 0 Td (depletion)Tj 4.6205 0 Td (experimen)Tj 4.9252 0 Td (ts)Tj 1.0985 0 Td (using)Tj 2.863 0 Td (trout)Tj 2.4662 0 Td (liver)Tj 2.2393 0 Td (spheroid)Tj 4.1741 0 Td (s.)Tj /F0 1 Tf 1.2614 0 Td (Substrate)Tj 4.4363 0 Td (decrease)Tj 4.2591 0 Td (over)Tj 2.133 0 Td (total)Tj 2.0764 0 Td (incubatio)Tj 3.919 0 Td (n)Tj 0.7653 0 Td (period)Tj 2.941 0 Td (\(%\),)Tj -64.5666 -1.1905 Td (depletion)Tj 4.1953 0 Td (rates)Tj 2.4023 0 Td (constant)Tj 3.9402 0 Td (\()Tj /F6 1 Tf (k)Tj /F0 1 Tf (;)Tj 1.3181 0 Td (h)Tj ET Q q 1 j 1 J 0 w 5.9998 0 0 5.3325 135.2125 702.7653 cm BT /F0 1 Tf 1 TL -0.0067 Tc 0 0 Td (-1)Tj ET Q q 1 j 1 J 0 w 7.9999 0 0 7.9999 140.4283 699.1937 cm BT /F0 1 Tf 1 TL -0.005 Tc 0 0 Td (\))Tj 0.5456 0 Td (and)Tj 1.8567 0 Td (half-life)Tj 3.3733 0 Td (\(t)Tj ET Q q 1 j 1 J 0 w 5.9998 0 0 5.3325 191.4519 697.8897 cm BT /F0 1 Tf 1 TL -0.0067 Tc 0 0 Td (1/2)Tj ET Q q 1 j 1 J 0 w 7.9999 0 0 7.9999 199.6724 699.1937 cm BT /F0 1 Tf 1 TL -0.005 Tc 0 0 Td (\))Tj 0.5456 0 Td (values)Tj 3.0544 0 Td (are)Tj 1.637 0 Td (shown)Tj 3.0614 0 Td (as)Tj 1.2615 0 Td (mean)Tj /F8 1 Tf 2.6787 0 Td [()]TJ /F0 1 Tf 0.7583 0 Td (SD.)Tj 1.8638 0 Td (NSD)Tj 2.3032 0 Td (=)Tj 0.7937 0 Td (no)Tj 1.311 0 Td (substrate)Tj 4.2662 0 Td (depletion.)Tj /F3 1 Tf 0 Tc -42.3499 -1.8496 Td (Pharm)Tj 3.0898 0 Td (aceutical)Tj 9.3757 0 Td (Categor)Tj 3.7559 0 Td (y)Tj 5.3149 0 Td (Log)Tj /F18 1 Tf 2.0623 0 Td (K)Tj ET Q q 1 j 1 J 0 w 5.9998 0 0 5.3325 243.7228 683.0362 cm BT /F3 1 Tf 1 TL 0 0 Td (ow)Tj ET Q q 1 j 1 J 0 w 7.9999 0 0 7.9999 253.9275 684.3968 cm BT /F3 1 Tf 1 TL 0 0 Td (\(pH\))Tj 5.3787 0 Td (%)Tj 1.1126 0 Td (decrease)Tj 4.5284 0 Td (over)Tj 2.3315 0 Td (total)Tj 5.9174 0 Td (Depletio)Tj 3.9331 0 Td (n)Tj 0.8433 0 Td (rate)Tj 5.6268 0 Td (Half-life)Tj 3.8835 0 Td (hours)Tj 3.0048 0 Td (\(t)Tj ET Q q 1 j 1 J 0 w 5.9998 0 0 5.3325 551.7354 683.0362 cm BT /F3 1 Tf 1 TL 0 0 Td (1/2)Tj ET Q q 1 j 1 J 0 w 7.9999 0 0 7.9999 560.0125 684.3968 cm BT /F3 1 Tf 1 TL 0 0 Td (\))Tj -32.0104 -1.6228 Td (incubati)Tj 3.8268 0 Td (on)Tj 1.4598 0 Td (period)Tj 7.3064 0 Td (constant)Tj 4.3866 0 Td (\()Tj /F18 1 Tf (k)Tj /F3 1 Tf (;)Tj 1.4457 0 Td (h)Tj ET Q q 1 j 1 J 0 w 5.9998 0 0 5.3325 456.2078 674.9291 cm BT /F3 1 Tf 1 TL 0 0 Td (-1)Tj ET Q q 1 j 1 J 0 w 7.9999 0 0 7.9999 461.537 671.4141 cm BT /F3 1 Tf 1 TL 0 0 Td (\))Tj /F0 1 Tf -49.6633 -1.6299 Td (Atenolo)Tj 3.359 0 Td (l)Tj 7.3631 0 Td (Selectiv)Tj 3.4725 0 Td (e)Tj 6.378 0 Td (0.02)Tj 2.1614 0 Td (\(7.4\))Tj 10.3465 0 Td (NSD)Tj 13.0324 0 Td (-)Tj 11.5654 0 Td (-)Tj -47.6223 -1.5591 Td (beta)Tj 2.1614 0 Td (blocker)Tj -13.9253 -1.5661 Td (Carbamaz)Tj 4.578 0 Td (epine)Tj 6.6331 0 Td (Anticonvul)Tj 4.578 0 Td (sant)Tj 6.4914 0 Td (2.47)Tj 2.1614 0 Td (\(7.0\))Tj 10.3465 0 Td (NSD)Tj 13.0324 0 Td (-)Tj 11.5654 0 Td (-)Tj -58.1248 -1.5591 Td (Diazepam)Tj 9.6521 0 Td (Benzodiazep)Tj 5.7331 0 Td (ine)Tj 5.6339 0 Td (2.70)Tj 2.1614 0 Td (\(7.0\))Tj 10.3465 0 Td (NSD)Tj 13.0324 0 Td (-)Tj 11.5654 0 Td (-)Tj -46.9845 -1.5661 Td (anxiolyti)Tj 3.5787 0 Td (c)Tj -16.5119 -1.5591 Td (Diclofen)Tj 3.5787 0 Td (ac)Tj 1.2827 0 Td (sodium)Tj 8.5891 0 Td (NSAID)Tj 9.3615 0 Td (4.02)Tj 2.1614 0 Td (\(7.0\))Tj 8.9646 0 Td (39.3)Tj /F8 1 Tf 2.1615 0 Td [()]TJ /F0 1 Tf 0.7724 0 Td (12.0)Tj 8.6599 0 Td (0.021)Tj /F8 1 Tf 2.7142 0 Td [()]TJ /F0 1 Tf 0.7725 0 Td (0.008)Tj 8.6385 0 Td (39.2)Tj /F8 1 Tf 2.1615 0 Td [()]TJ /F0 1 Tf 0.7653 0 Td (22.4)Tj -57.331 -1.5661 Td (salt)Tj -1.5378 -1.5591 Td (Metopr)Tj 3.0897 0 Td (olol)Tj 8.1568 0 Td (Selectiv)Tj 3.4725 0 Td (e)Tj 6.378 0 Td (0.09)Tj 2.1614 0 Td (\(7.4\))Tj 10.3465 0 Td (NSD)Tj 13.0324 0 Td (-)Tj 11.5654 0 Td (-)Tj -57.9901 -1.5662 Td (succinate)Tj 10.3678 0 Td (beta)Tj 2.1614 0 Td (blocker)Tj -13.982 -1.559 Td (Phenyl)Tj 3.026 0 Td (butazone)Tj 9.9497 0 Td (NSAID)Tj 9.3615 0 Td (3.16)Tj 2.1614 0 Td (\(7.4\))Tj 8.9646 0 Td (34.4)Tj /F8 1 Tf 2.1615 0 Td [()]TJ /F0 1 Tf 0.7724 0 Td (12.9)Tj 8.6599 0 Td (0.015)Tj /F8 1 Tf 2.7142 0 Td [()]TJ /F0 1 Tf 0.7725 0 Td (0.006)Tj 8.6385 0 Td (51.0)Tj /F8 1 Tf 2.1615 0 Td [()]TJ /F0 1 Tf 0.7653 0 Td (22.9)Tj -60.0311 -1.5662 Td (Propranolol)Tj 5.3009 0 Td (HCl)Tj 6.1158 0 Td (Non-sele)Tj 3.9614 0 Td (ctive)Tj 6.8812 0 Td (0.72)Tj 2.1614 0 Td (\(7.0\))Tj 9.3828 0 Td (41)Tj /F8 1 Tf 1.3252 0 Td [()]TJ /F0 1 Tf 0.7724 0 Td (15.8)Tj 9.078 0 Td (0.022)Tj /F8 1 Tf 2.7142 0 Td [()]TJ /F0 1 Tf 0.7725 0 Td (0.010)Tj 8.6385 0 Td (39.4)Tj /F8 1 Tf 2.1615 0 Td [()]TJ /F0 1 Tf 0.7653 0 Td (23.9)Tj -48.2884 -1.5591 Td (beta)Tj 2.1614 0 Td (blocker)Tj /F10 1 Tf -0.005 Tc -15.7466 -1.8779 Td (doi:)Tj -0.025 Tc (10.137)Tj 4.0323 0 Td (1/journal.pone.)Tj 5.556 0 Td (0168837.t)Tj 3.7913 0 Td (001)Tj ET Q q 0.45 0.36 0.35 0.01 k 1 j 1 J 0 w 36 256.5023 m 576 256.5023 l 576 256.0022 l 36 256.0022 l f* 104.7427 256.0022 m 104.7427 211.0022 l 104.2427 211.5023 l 104.2427 256.0022 l f* 104.7427 211.0022 m 36 211.0022 l 36 211.5023 l 104.2427 211.5023 l f* 168.228 256.0022 m 168.228 211.0022 l 167.728 211.5023 l 167.728 256.0022 l f* 168.228 211.0022 m 104.7427 211.0022 l 104.7427 211.5023 l 167.728 211.5023 l f* 224.6536 256.0022 m 224.6536 233.5022 l 224.1536 234.0023 l 224.1536 256.0022 l f* 224.6536 233.5022 m 168.228 233.5022 l 168.228 234.0023 l 224.1536 234.0023 l f* 437.3266 256.0022 m 437.3266 233.5022 l 436.8266 234.0023 l 436.8266 256.0022 l f* 437.3266 233.5022 m 224.6536 233.5022 l 224.6536 234.0023 l 436.8266 234.0023 l f* 533.6983 256.0022 m 533.6983 233.5022 l 533.1983 234.0023 l 533.1983 256.0022 l f* 533.6983 233.5022 m 437.3266 233.5022 l 437.3266 234.0023 l 533.1983 234.0023 l f* 576 211.0022 m 533.6983 211.0022 l 533.6983 211.5023 l 576 211.5023 l f* 224.6536 233.5022 m 224.6536 211.0022 l 224.1536 211.5023 l 224.1536 233.5022 l f* 224.6536 211.0022 m 168.228 211.0022 l 168.228 211.5023 l 224.1536 211.5023 l f* 437.3266 233.5022 m 437.3266 211.0022 l 436.8266 211.5023 l 436.8266 233.5022 l f* 437.3266 211.0022 m 224.6536 211.0022 l 224.6536 211.5023 l 436.8266 211.5023 l f* 475.2272 233.5022 m 475.2272 211.0022 l 474.7272 211.5023 l 474.7272 233.5022 l f* 475.2272 211.0022 m 437.3266 211.0022 l 437.3266 211.5023 l 474.7272 211.5023 l f* 533.6983 233.5022 m 533.6983 211.0022 l 533.1983 211.5023 l 533.1983 233.5022 l f* 533.6983 211.0022 m 475.2272 211.0022 l 475.2272 211.5023 l 533.1983 211.5023 l f* 104.7427 211.0022 m 104.7427 198.5023 l 104.2427 199.0023 l 104.2427 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(to)Tj 1.0261 0 Td (the)Tj 1.4683 0 Td (five-fold)Tj 3.5773 0 Td (measured)Tj 4.1046 0 Td (variability)Tj 4.2235 0 Td (in)Tj 1.0374 0 Td (cir-)Tj -36.0677 -1.2983 Td (culating)Tj 3.4299 0 Td (propranolol)Tj 4.9946 0 Td (concentrations)Tj 6.1795 0 Td (already)Tj 3.1125 0 Td (reported)Tj 3.6566 0 Td (in)Tj 1.0375 0 Td (trout)Tj 2.2223 0 Td ([)Tj 0.83 0.64 0.02 0 k (32)Tj 0 g (].)Tj 2.075 0 Td (Given)Tj 2.6305 0 Td (our)Tj 1.6271 0 Td (understanding)Tj -30.9655 -1.3039 Td (of)Tj 1.0148 0 Td (the)Tj 1.4684 0 Td (variability)Tj 4.2236 0 Td (between)Tj 3.5262 0 Td (individuals)Tj 4.6488 0 Td (for)Tj 1.389 0 Td (propranolol,)Tj 5.2157 0 Td (and)Tj 1.7291 0 Td (balancing)Tj 4.0932 0 Td (this)Tj 1.6781 0 Td (against)Tj 3.0274 0 Td (the)Tj 1.4684 0 Td (numbers)Tj -33.4827 -1.2983 Td (of)Tj 1.0148 0 Td (fish)Tj 1.6611 0 Td (required,)Tj 3.8665 0 Td (we)Tj 1.3266 0 Td (suggest)Tj 3.1237 0 Td (two)Tj 1.7065 0 Td (fish)Tj 1.6667 0 Td (\(biological)Tj 4.4277 0 Td (replicates\))Tj 4.3257 0 Td (are)Tj 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605.3893 m 394.0883 605.3893 l 394.0883 605.8894 l 464.2773 605.8894 l f* 576 605.3893 m 464.7773 605.3893 l 464.7773 605.8894 l 576 605.8894 l f* 118.925 605.3893 m 118.925 592.8894 l 118.425 593.3894 l 118.425 605.3893 l f* 118.925 592.8894 m 36 592.8894 l 36 593.3894 l 118.425 593.3894 l f* 295.4625 605.3893 m 295.4625 592.8894 l 294.9625 593.3894 l 294.9625 605.3893 l f* 295.4625 592.8894 m 118.925 592.8894 l 118.925 593.3894 l 294.9625 593.3894 l f* 394.0883 605.3893 m 394.0883 592.8894 l 393.5883 593.3894 l 393.5883 605.3893 l f* 394.0883 592.8894 m 295.4625 592.8894 l 295.4625 593.3894 l 393.5883 593.3894 l f* 464.7773 605.3893 m 464.7773 592.8894 l 464.2773 593.3894 l 464.2773 605.3893 l f* 464.7773 592.8894 m 394.0883 592.8894 l 394.0883 593.3894 l 464.2773 593.3894 l f* 576 592.8894 m 464.7773 592.8894 l 464.7773 593.3894 l 576 593.3894 l f* 118.925 592.8894 m 118.925 580.3894 l 118.425 580.8895 l 118.425 592.8894 l f* 118.925 580.3894 m 36 580.3894 l 36 580.8895 l 118.425 580.8895 l f* 295.4625 592.8894 m 295.4625 580.3894 l 294.9625 580.8895 l 294.9625 592.8894 l f* 295.4625 580.3894 m 118.925 580.3894 l 118.925 580.8895 l 294.9625 580.8895 l f* 394.0883 592.8894 m 394.0883 580.3894 l 393.5883 580.8895 l 393.5883 592.8894 l f* 394.0883 580.3894 m 295.4625 580.3894 l 295.4625 580.8895 l 393.5883 580.8895 l f* 464.7773 592.8894 m 464.7773 580.3894 l 464.2773 580.8895 l 464.2773 592.8894 l f* 464.7773 580.3894 m 394.0883 580.3894 l 394.0883 580.8895 l 464.2773 580.8895 l f* 576 580.3894 m 464.7773 580.3894 l 464.7773 580.8895 l 576 580.8895 l f* 118.925 580.3894 m 118.925 567.8895 l 118.425 568.3895 l 118.425 580.3894 l f* 118.925 567.8895 m 36 567.8895 l 36 568.3895 l 118.425 568.3895 l f* 295.4625 580.3894 m 295.4625 567.8895 l 294.9625 568.3895 l 294.9625 580.3894 l f* 295.4625 567.8895 m 118.925 567.8895 l 118.925 568.3895 l 294.9625 568.3895 l f* 394.0883 580.3894 m 394.0883 567.8895 l 393.5883 568.3895 l 393.5883 580.3894 l f* 394.0883 567.8895 m 295.4625 567.8895 l 295.4625 568.3895 l 393.5883 568.3895 l f* 464.7773 580.3894 m 464.7773 567.8895 l 464.2773 568.3895 l 464.2773 580.3894 l f* 464.7773 567.8895 m 394.0883 567.8895 l 394.0883 568.3895 l 464.2773 568.3895 l f* 576 567.8895 m 464.7773 567.8895 l 464.7773 568.3895 l 576 568.3895 l f* 118.925 567.8895 m 118.925 555.3896 l 118.425 555.8896 l 118.425 567.8895 l f* 118.925 555.3896 m 36 555.3896 l 36 555.8896 l 118.425 555.8896 l f* 295.4625 567.8895 m 295.4625 555.3896 l 294.9625 555.8896 l 294.9625 567.8895 l f* 295.4625 555.3896 m 118.925 555.3896 l 118.925 555.8896 l 294.9625 555.8896 l f* 394.0883 567.8895 m 394.0883 555.3896 l 393.5883 555.8896 l 393.5883 567.8895 l f* 394.0883 555.3896 m 295.4625 555.3896 l 295.4625 555.8896 l 393.5883 555.8896 l f* 464.7773 567.8895 m 464.7773 555.3896 l 464.2773 555.8896 l 464.2773 567.8895 l f* 464.7773 555.3896 m 394.0883 555.3896 l 394.0883 555.8896 l 464.2773 555.8896 l f* 576 555.3896 m 464.7773 555.3896 l 464.7773 555.8896 l 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464.2773 530.3897 l f* 464.7773 517.8898 m 394.0883 517.8898 l 394.0883 518.3898 l 464.2773 518.3898 l f* 576 517.8898 m 464.7773 517.8898 l 464.7773 518.3898 l 576 518.3898 l f* 118.925 517.8898 m 118.925 505.3898 l 118.425 505.8899 l 118.425 517.8898 l f* 118.925 505.3898 m 36 505.3898 l 36 505.8899 l 118.425 505.8899 l f* 295.4625 517.8898 m 295.4625 505.3898 l 294.9625 505.8899 l 294.9625 517.8898 l f* 295.4625 505.3898 m 118.925 505.3898 l 118.925 505.8899 l 294.9625 505.8899 l f* 394.0883 517.8898 m 394.0883 505.3898 l 393.5883 505.8899 l 393.5883 517.8898 l f* 394.0883 505.3898 m 295.4625 505.3898 l 295.4625 505.8899 l 393.5883 505.8899 l f* 464.7773 517.8898 m 464.7773 505.3898 l 464.2773 505.8899 l 464.2773 517.8898 l f* 464.7773 505.3898 m 394.0883 505.3898 l 394.0883 505.8899 l 464.2773 505.8899 l f* 576 505.3898 m 464.7773 505.3898 l 464.7773 505.8899 l 576 505.8899 l f* 118.925 505.3898 m 118.925 492.8899 l 118.425 493.3899 l 118.425 505.3898 l f* 118.925 492.8899 m 36 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Td (has)Tj 1.542 0 Td (demonstrated)Tj 5.76 0 Td (extensive)Tj 3.8834 0 Td (metabolism)Tj 4.9039 0 Td (in)Tj 1.0375 0 Td (both)Tj 2.058 0 Td (humans)Tj 3.4412 0 Td ([)Tj 0.83 0.64 0.02 0 k (37)Tj 0 g (])Tj 1.8482 0 Td (and)Tj 1.7291 0 Td (horses)Tj 2.7723 0 Td ([)Tj 0.83 0.64 0.02 0 k (38)Tj 0 g (])Tj 1.8538 0 Td (pre-)Tj -35.4101 -1.2983 Td (viously,)Tj 3.2598 0 Td (but)Tj 1.5533 0 Td (we)Tj 1.3323 0 Td (are)Tj 1.4457 0 Td (aware)Tj 2.5681 0 Td (of)Tj 1.0148 0 Td (no)Tj 1.2756 0 Td (studies)Tj 2.9877 0 Td (except)Tj 2.7666 0 Td (the)Tj 1.474 0 Td (current)Tj 3.1805 0 Td (on)Tj 1.2756 0 Td (fish.)Tj 1.8935 0 Td (Little)Tj 2.2904 0 Td (seems)Tj 2.6078 0 Td (to)Tj 1.0262 0 Td (be)Tj 1.1508 0 Td (known)Tj -33.1027 -1.3039 Td (about)Tj 2.4944 0 Td (exactly)Tj 2.965 0 Td (which)Tj 2.6476 0 Td (cytochrome)Tj 4.9776 0 Td (enzymes)Tj 3.6623 0 Td (are)Tj 1.4513 0 Td (involved)Tj 3.651 0 Td (in)Tj 1.0319 0 Td (metabolism)Tj 4.9039 0 Td (of)Tj 1.0148 0 Td (phenylbutazone,)Tj 6.8257 0 Td (but)Tj -35.6255 -1.2982 Td (it)Tj 0.7824 0 Td (seems)Tj 2.6078 0 Td (likely)Tj 2.3584 0 Td (that)Tj 1.7744 0 Td (2D6,)Tj 2.1373 0 Td (2C19,)Tj 2.5342 0 Td (3A4)Tj 1.8539 0 Td (are)Tj 1.4513 0 Td (the)Tj 1.4683 0 Td (primary)Tj 3.4526 0 Td (enzymes)Tj 3.668 0 Td (in)Tj 1.0318 0 Td (man;)Tj 2.2507 0 Td (phenylbutazone)Tj 6.599 0 Td (is)Tj 0.8447 0 Td (a)Tj 0.652 0 Td (well-)Tj -35.4668 -1.2983 Td (documented)Tj 5.244 0 Td (strong)Tj 2.7723 0 Td (inhibitor)Tj 3.7814 0 Td (of)Tj 1.0148 0 Td (human)Tj 3.0784 0 Td (liver)Tj 1.9842 0 Td (microsomal)Tj 4.9776 0 Td (CYP2C9)Tj 3.685 0 Td (activity)Tj 3.1181 0 Td ([)Tj 0.83 0.64 0.02 0 k (39)Tj 0 g (].)Tj -28.4596 -1.3039 Td (No)Tj 1.4683 0 Td (substrate)Tj 3.7984 0 Td (depletion)Tj 3.9798 0 Td (of)Tj 1.0148 0 Td (the)Tj 1.4683 0 Td (anticonvulsant)Tj 6.1172 0 Td (carbamazepine,)Tj 6.4629 0 Td (or)Tj 1.0999 0 Td (the)Tj 1.4683 0 Td (benzodiazepine)Tj 6.4403 0 Td (anxio-)Tj -34.5144 -1.2983 Td (lytic)Tj 1.9105 0 Td (diazepam)Tj 4.0535 0 Td (was)Tj 1.7008 0 Td (measured)Tj 4.1102 0 Td (in)Tj 1.0318 0 Td (any)Tj 1.6611 0 Td (experiments.)Tj 5.3631 0 Td (No)Tj 1.4627 0 Td (measurable)Tj 4.7678 0 Td (metabolism)Tj 4.9039 0 Td (of)Tj 1.0148 0 Td (carbamaze-)Tj -31.9802 -1.2982 Td (pine)Tj 1.9728 0 Td (in)Tj 1.0375 0 Td (fish)Tj 1.6668 0 Td (liver)Tj 1.9785 0 Td (S9)Tj 1.1736 0 Td (fractions,)Tj 3.9458 0 Td (a)Tj 0.6519 0 Td (substrate)Tj 3.8041 0 Td (for)Tj 1.3833 0 Td (CYP3A4)Tj 3.7077 0 Td (in)Tj 1.0375 0 Td (humans,)Tj 3.6623 0 Td (has)Tj 1.5477 0 Td (also)Tj 1.7632 0 Td (been)Tj 2.1259 0 Td (reported)Tj -31.4586 -1.2983 Td (recently)Tj 3.4072 0 Td ([)Tj 0.83 0.64 0.02 0 k (2)Tj 0 g (].)Tj 1.6044 0 Td (These)Tj 2.5625 0 Td (authors)Tj 3.2484 0 Td (also)Tj 1.7689 0 Td (suggest)Tj 3.1237 0 Td (that)Tj 1.7745 0 Td (differences)Tj 4.5694 0 Td (in)Tj 1.0318 0 Td (CYP3A)Tj 3.2372 0 Td (specificity)Tj 4.2122 0 Td (between)Tj 3.5263 0 Td (trout)Tj -34.0665 -1.3039 Td (and)Tj 1.7291 0 Td (mammals)Tj 4.1555 0 Td (could)Tj 2.4491 0 Td (lead)Tj 1.8539 0 Td (to)Tj 1.0261 0 Td (an)Tj 1.2019 0 Td (absence)Tj 3.3392 0 Td (of)Tj 1.0148 0 Td (CYP3A4-like)Tj 5.4935 0 Td (activity)Tj 3.1181 0 Td (in)Tj 1.0375 0 Td (trout,)Tj 2.4491 0 Td (and)Tj 1.7291 0 Td (that)Tj 1.7745 0 Td (trout)Tj 2.228 0 Td (and)Tj -34.5994 -1.2983 Td (other)Tj 2.347 0 Td (fish)Tj 1.6611 0 Td (species)Tj 2.999 0 Td (may)Tj 1.9276 0 Td (metabolise)Tj 4.507 0 Td (some,)Tj 2.5569 0 Td (but)Tj 1.5534 0 Td (not)Tj 1.576 0 Td (all,)Tj 1.372 0 Td (mammalian)Tj 5.0399 0 Td (CYP3A)Tj 3.2372 0 Td (substrates)Tj 4.1612 0 Td (\(but)Tj 1.8935 0 Td (see)Tj -34.8318 -1.2983 Td (phenylbutazone)Tj 6.5933 0 Td (above\),)Tj 3.1124 0 Td (instead)Tj 3.0841 0 Td (utilizing)Tj 3.5206 0 Td (enzymes)Tj 3.6623 0 Td (from)Tj 2.2054 0 Td (other)Tj 2.347 0 Td (CYP)Tj 2.075 0 Td (families)Tj 3.3278 0 Td (\(e.g.)Tj 1.8992 0 Td (CYP1A\).)Tj -31.8271 -1.3039 Td (CYP3A4)Tj 3.7076 0 Td (has)Tj 1.5421 0 Td (not)Tj 1.576 0 Td (been)Tj 2.1203 0 Td (identified)Tj 4.0592 0 Td (in)Tj 1.0375 0 Td (rainbow)Tj 3.5376 0 Td (trout)Tj 2.2223 0 Td (previously)Tj 4.354 0 Td ([)Tj 0.83 0.64 0.02 0 k (29)Tj 0 g (].)Tj 2.075 0 Td (Several)Tj 3.05 0 Td (studies)Tj 2.9821 0 Td (have)Tj 2.0636 0 Td (demon-)Tj -34.3273 -1.2982 Td (strated)Tj 2.9309 0 Td (the)Tj 1.474 0 Td (involvement)Tj 5.2101 0 Td (of)Tj 1.0148 0 Td (CYP2C)Tj 3.2145 0 Td (and)Tj 1.7291 0 Td (CYP3A)Tj 3.2315 0 Td (sub-families)Tj 5.0739 0 Td (in)Tj 1.0375 0 Td (human)Tj 3.0784 0 Td (liver)Tj 1.9786 0 Td (microsomal)Tj 4.9776 0 Td (diaze-)Tj -34.9509 -1.2983 Td (pam)Tj 1.9898 0 Td (metabolism,)Tj 5.1307 0 Td (with)Tj 1.9956 0 Td (3-hydroxylation)Tj 6.6557 0 Td (catalyzed)Tj 3.8721 0 Td (primarily)Tj 3.9685 0 Td (by)Tj 1.1849 0 Td (3A)Tj 1.3776 0 Td (P450s)Tj 2.5682 0 Td (and)Tj /F13 1 Tf 1.7291 0 Td [()]TJ /F7 1 Tf (-demethylation)Tj -30.4722 -1.3039 Td (partially)Tj 3.4865 0 Td (mediated)Tj 3.9402 0 Td (by)Tj 1.1848 0 Td (2C)Tj 1.3607 0 Td (P450s)Tj 2.5625 0 Td ([)Tj 0.83 0.64 0.02 0 k (40)Tj 0 g ()Tj 0.83 0.64 0.02 0 k (42)Tj 0 g (].)Tj -11.3385 -1.2983 Td (The)Tj 1.7858 0 Td (approach)Tj 3.9514 0 Td (of)Tj 1.0148 0 Td (studying)Tj 3.668 0 Td (the)Tj 1.474 0 Td (metabolism)Tj 4.8983 0 Td (of)Tj 1.0148 0 Td (pharmaceuticals)Tj 6.7294 0 Td (in)Tj 1.0375 0 Td (aquatic)Tj 3.1124 0 Td (organisms)Tj 4.354 0 Td (via)Tj 1.3776 0 Td (the)Tj -35.6142 -1.2983 Td (read-across)Tj 5.5671 0 Td (of)Tj 1.0148 0 Td (mammalian)Tj 5.0457 0 Td (toxicity)Tj 3.1974 0 Td (and)Tj 1.7292 0 Td (detoxification)Tj 5.7429 0 Td (systems)Tj 3.2995 0 Td (is)Tj 0.8504 0 Td (important)Tj 4.2803 0 Td (when)Tj 2.4038 0 Td (such)Tj 2.0579 0 Td (little)Tj -35.189 -1.2982 Td (data)Tj 1.9105 0 Td (exists)Tj 2.3981 0 Td (on)Tj 1.2756 0 Td (these)Tj 2.2563 0 Td (systems)Tj 3.2995 0 Td (in)Tj 1.0318 0 Td (fish)Tj 1.6668 0 Td ([)Tj 0.83 0.64 0.02 0 k (3)Tj 0 g (,)Tj 0.83 0.64 0.02 0 k 1.2586 0 Td (4)Tj 0 g (,)Tj 0.83 0.64 0.02 0 k 0.9241 0 Td (21)Tj 0 g (,)Tj 0.83 0.64 0.02 0 k 1.3946 0 Td (31)Tj 0 g (,)Tj 0.83 0.64 0.02 0 k 1.3946 0 Td (43)Tj 0 g (,)Tj 0.83 0.64 0.02 0 k 1.4003 0 Td (44)Tj 0 g (].)Tj 1.7348 0 Td (With)Tj 2.2791 0 Td (reference)Tj 3.9174 0 Td (to)Tj 1.0262 0 Td (published)Tj 4.1215 0 Td (pharma-)Tj -33.2898 -1.3039 Td (ceutical)Tj 3.2598 0 Td (metabolism)Tj 4.9039 0 Td (data)Tj 1.9162 0 Td (from)Tj 2.2053 0 Td (humans)Tj 3.4413 0 Td (and)Tj 1.7291 0 Td (fish)Tj 1.6611 0 Td (\(both)Tj /F13 1 Tf 2.4037 0 Td [()12()]TJ 1.0148 0 Td [()-13()15()3()]TJ /F7 1 Tf 1.8199 0 Td (and)Tj /F13 1 Tf 1.7291 0 Td [()12()]TJ 1.0148 0 Td [()-13()14()7()20()]TJ /F7 1 Tf (\))Tj 2.3867 0 Td (and)Tj 1.7292 0 Td (with)Tj 1.9955 0 Td (particular)Tj -33.2104 -1.2983 Td (reference)Tj 3.9117 0 Td (to)Tj 1.0148 0 Td (the)Tj 1.4684 0 Td (substrate)Tj 3.7927 0 Td (/)Tj 0.5442 0 Td (CYP)Tj 2.0693 0 Td (relationship)Tj 4.9833 0 Td (\()Tj 0.83 0.64 0.02 0 k (Table)Tj 2.7723 0 Td (2)Tj 0 g (\),)Tj 1.2585 0 Td (data)Tj 1.9049 0 Td (acquired)Tj 3.6964 0 Td (from)Tj 2.1996 0 Td (this)Tj 1.6725 0 Td (and)Tj 1.7234 0 Td (from)Tj 2.1997 0 Td (previ-)Tj -35.2117 -1.2983 Td (ous)Tj /F13 1 Tf 1.6157 0 Td [()12()]TJ 1.0148 0 Td [()-13()14()7()20()]TJ /F7 1 Tf 2.0466 0 Td (fish)Tj 1.6611 0 Td (metabolism)Tj 4.9039 0 Td (studies,)Tj 3.2088 0 Td (highlights)Tj 4.1782 0 Td (the)Tj 1.4683 0 Td (degree)Tj 2.8517 0 Td (of)Tj 1.0148 0 Td (caution)Tj 3.2258 0 Td (that)Tj 1.7801 0 Td (must)Tj 2.2281 0 Td (be)Tj 1.1508 0 Td (taken)Tj 2.4208 0 Td (when)Tj -34.7695 -1.3039 Td (presuming)Tj 4.5183 0 Td (a)Tj 0.6577 0 Td (homology)Tj 4.2519 0 Td (of)Tj 1.0148 0 Td (metabolic)Tj 4.1442 0 Td (pathways)Tj 3.9345 0 Td (between)Tj 3.5263 0 Td (aquatic)Tj 3.1124 0 Td (and)Tj 1.7291 0 Td (terrestrial)Tj 4.0875 0 Td (species)Tj 2.9991 0 Td ([)Tj 0.83 0.64 0.02 0 k (2)Tj 0 g (].)Tj -33.9758 -1.2982 Td (Given)Tj 2.6305 0 Td (the)Tj 1.4683 0 Td (species)Tj 2.9934 0 Td (differences)Tj 4.5694 0 Td (and)Tj 1.7291 0 Td (physiological)Tj 5.4425 0 Td (/)Tj 0.5499 0 Td (environmental)Tj 6.1115 0 Td (factors)Tj 2.9026 0 Td (such)Tj 2.058 0 Td (as)Tj 1.0148 0 Td (temperature,)Tj -31.47 -1.2983 Td (direct)Tj 2.5284 0 Td (comparisons)Tj 5.3405 0 Td (of)Tj 1.0148 0 Td (biotransformation)Tj 7.5514 0 Td (and)Tj 1.7348 0 Td (kinetics)Tj 3.3052 0 Td (remain)Tj 3.0841 0 Td (to)Tj 1.0204 0 Td (be)Tj 1.1509 0 Td (further)Tj 3.0274 0 Td (investigated.)Tj 5.2157 0 Td (Of)Tj 1.2585 0 Td (the)Tj -36.2321 -1.3039 Td (seven)Tj 2.432 0 Td (pharmaceuticals)Tj 6.7295 0 Td (tested,)Tj 2.7722 0 Td (four)Tj 1.9162 0 Td (\(propranolol,)Tj 5.5616 0 Td (diclofenac,)Tj 4.5297 0 Td (phenylbutazone)Tj 6.599 0 Td (and)Tj 1.7291 0 Td (atenolol\))Tj -32.2693 -1.2983 Td (demonstrated)Tj 5.7599 0 Td (predicted)Tj 3.9968 0 Td (substrate)Tj 3.8041 0 Td (depletion)Tj 3.9798 0 Td (based)Tj 2.4718 0 Td (on)Tj 1.2756 0 Td (read-across)Tj 4.7848 0 Td (to)Tj 1.0262 0 Td (human)Tj 3.0784 0 Td (metabolism)Tj 4.9039 0 Td (data)Tj -35.0813 -1.2983 Td ([)Tj 0.83 0.64 0.02 0 k (2)Tj 0 g (,)Tj 0.83 0.64 0.02 0 k 1.2585 0 Td (45)Tj 0 g ()Tj 0.83 0.64 0.02 0 k (48)Tj 0 g (].)Tj -0.0623 -1.3039 Td (The)Tj 1.7858 0 Td (enzyme)Tj 3.2995 0 Td (CYP1A2)Tj 3.7133 0 Td (acts)Tj 1.7348 0 Td (on)Tj 1.2756 0 Td (both)Tj 2.0636 0 Td (propranolol)Tj 4.989 0 Td (and)Tj 1.7291 0 Td (diclofenac)Tj 4.3086 0 Td (as)Tj 1.0148 0 Td (its)Tj 1.1509 0 Td (major)Tj 2.6078 0 Td (and)Tj 1.7292 0 Td (minor)Tj 2.7325 0 Td (sub-)Tj -35.3307 -1.2982 Td (strate)Tj 2.4037 0 Td (respectively,)Tj 5.1137 0 Td (with)Tj 1.9955 0 Td (the)Tj 1.4684 0 Td (latter)Tj 2.2904 0 Td (having)Tj 2.9196 0 Td (several)Tj 2.9367 0 Td (CYP)Tj 2.0693 0 Td (enzymes)Tj 3.668 0 Td (implicated)Tj 4.4447 0 Td (in)Tj 1.0318 0 Td (its)Tj 1.1509 0 Td (metabolism)Tj -31.4927 -1.2983 Td ([CYP2B6,)Tj 4.1668 0 Td (CYP2C8,)Tj 3.9175 0 Td (CYP2C9,)Tj 3.9118 0 Td (CYP2C19,)Tj 4.3937 0 Td (CYP2D6)Tj 3.7587 0 Td (and)Tj 1.7291 0 Td (CYP3A4])Tj 4.0535 0 Td (in)Tj 1.0318 0 Td (humans)Tj 3.4413 0 Td ([)Tj 0.83 0.64 0.02 0 k (2)Tj 0 g (].)Tj 1.5987 0 Td (Trout)Tj 2.5398 0 Td (liver)Tj -34.5427 -1.2983 Td (spheroids)Tj 4.0818 0 Td 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2000 Adobe Systems Incorporated. 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H+DM  yurs~cgielemlhhrr \|`avchHYX Xvv^ 4ɁZX'cbq~  SP#y*uMatһpyvvɋwOw ) =:?# ގuwst{uo~z )vtҸɾ n~z Ǎ_hxs}qzkaeo[ x~~ohep`buumfwqچ{6YLu múu2*Drq~_ | [j L uubnt V űjlrtxt 9w Kx)ʧ|bZ_ q <}#F  {jz{z jjjuJ#Պ "xv v B  e  SO#x*vMbt ;:{ҭoXT~xӁ`{]gJP rhn{rt|q] vF> endobj 606 0 obj <>stream /CIDInit/ProcSet findresource begin 12 dict begin begincmap /CMapName/Adobe-Identity-UCS def /CIDSystemInfo<>def /CMapType 2 def 1 begincodespacerange <00>endcodespacerange 1 beginbfrange <01><13>[<0069><006E><0076><0074><0072><006F><0073> <006C><0063><004F><0068><0079><0075><006D><006B> <0044><0061><0065><004E>]endbfrange endcmap CMapName currentdict /CMap defineresource pop end end endstream endobj 11 0 obj <> endobj 608 0 obj <> endobj 609 0 obj <>stream %!PS-AdobeFont-1.0 11 dict begin /FontName /TeX_CM_Maths_Symbols def /FontType 1 def /FontBBox {-20 -958 1114 770} readonly def /FontMatrix [0.001 0 0 0.001 0 0] readonly def /PaintType 0 def /FontInfo 8 dict dup begin /FullName (TeX_CM_Maths_Symbols) readonly def /BaseFontName (TeX_CM_Maths_Symbols) def end def /Encoding 256 array 0 1 255 {1 index exch /.notdef put} for dup 0 /C0 put dup 1 /C1 put dup 2 /C2 put dup 3 /C3 put dup 4 /C4 put dup 5 /C5 put dup 6 /C6 put dup 7 /C7 put dup 8 /C8 put dup 9 /C9 put dup 10 /C10 put dup 11 /C11 put dup 12 /C12 put dup 13 /C13 put dup 14 /C14 put dup 15 /C15 put dup 16 /C16 put dup 17 /C17 put dup 18 /C18 put dup 19 /C19 put dup 20 /C20 put dup 21 /C21 put dup 22 /C22 put dup 23 /C23 put dup 24 /C24 put dup 25 /C25 put dup 26 /C26 put dup 27 /C27 put dup 28 /C28 put dup 29 /C29 put dup 30 /C30 put dup 31 /C31 put dup 32 /space put dup 33 /exclam put dup 34 /quotedbl put dup 35 /numbersign put dup 36 /dollar put dup 37 /percent put dup 38 /ampersand put dup 39 /quoteright put dup 40 /parenleft put dup 41 /parenright put dup 42 /asterisk put dup 43 /plus put dup 44 /comma put dup 45 /hyphen put dup 46 /period put dup 47 /slash put dup 48 /zero put dup 49 /one put dup 50 /two put dup 51 /three put dup 52 /four put dup 53 /five put dup 54 /six put dup 55 /seven put dup 56 /eight put dup 57 /nine put dup 58 /colon put dup 59 /semicolon put dup 60 /less put dup 61 /equal put dup 62 /greater put dup 63 /question put dup 64 /at put dup 65 /A put dup 66 /B put dup 67 /C put dup 68 /D put dup 69 /E put dup 70 /F put dup 71 /G put dup 72 /H put dup 73 /I put dup 74 /J put dup 75 /K put dup 76 /L put dup 77 /M put dup 78 /N put dup 79 /O put dup 80 /P put dup 81 /Q put dup 82 /R put dup 83 /S put dup 84 /T put dup 85 /U put dup 86 /V put dup 87 /W put dup 88 /X put dup 89 /Y put dup 90 /Z put dup 91 /bracketleft put dup 92 /backslash put dup 93 /bracketright put dup 94 /asciicircum put dup 95 /underscore put dup 96 /quoteleft put dup 97 /a put dup 98 /b put dup 99 /c put dup 100 /d put dup 101 /e put dup 102 /f put dup 103 /g put dup 104 /h put dup 105 /i put dup 106 /j put dup 107 /k put dup 108 /l put dup 109 /m put dup 110 /n put dup 111 /o put dup 112 /p put dup 113 /q put dup 114 /r put dup 115 /s put dup 116 /t put dup 117 /u put dup 118 /v put dup 119 /w put dup 120 /x put dup 121 /y put dup 122 /z put dup 123 /braceleft put dup 124 /bar put dup 125 /braceright put dup 126 /asciitilde put dup 127 /Euro put dup 128 /ff put dup 129 /ffi put dup 130 /ffl put dup 131 /C131 put dup 132 /Eth put dup 133 /eth put dup 134 /Thorn put dup 135 /thorn put dup 136 /onequarter put dup 137 /onehalf put dup 138 /C138 put readonly def currentdict end currentfile eexec M#1H5 J6o \&rtS(#v\0\޹V7Fe༙OYx5-cY9^%Y6 (efIOldN"wȰ;)UƽoFg/rvV$JS8_oc@  o9-eGJp}[Do]mN=4*{ܯq=eU^t6¤(HwK7X 7 Mr:E%]3<Ӝ$wrAQ4ADt%̏>E hAجm*pu@>#6aZi}NRmƼ% ,Og X' EX?ڞ\ #JEG<IXS}Eh[ş8ї48ٶ.w4bJ?_nfulqD?둓\C%+'˜ { L9K7isW+ӕ(6oɧVҺlS;5K Z%.oQՕW*9Qk_S +B-}%lYC@WP0b\KKdi>t,n_S['9`-z+cڦEb#c@;yɸoAT O_H~i -6ϰ豟Ae&BF+ wNX!= hhUF 8(hZ6pgJc m'9dx*^wXc գ<.쯶c l n)/LvXY2jbF:ȸ3'>\Ȥmzj,!:ZK'(q/ -&&S ؤ-bmKQSxLGu`D3yԱKaVMU§%iq5%s2SdR#ho45H.4TdՊ a<K>BqG- Ao, (e&F2gG`z8*༠& x#B B;8!93~T/ \>nLzCĭSK,!_<ӾX@X@N2vEt בFmBYawRG[i;+oM+%(8jԀlIW>ӧ R-CD@B!gX2p+PwSB=|ηNfr0x m3\HrE2 DfVlIll 6{A8Ul%YV")ِ5̷՗* B"dBiMY)#0:n$]iy+ \*7e~٧$_2`qg;F2c!7aKBDRZ:{ޟyN8VQ`.| _M4mڄڒQdGh?'T ]}@rJJj g-+8'q+ 9 /ExXzLᬥqҍM4UˌAHϒ̛Tvw`L05jgIlO;8dFɃ'.̓맓ѓa;EDmh1THPtHvks|}M Oozr{bNq#ѪqqB 6j(JՋ&$ ͸^\PlP^cM1XX|"t8#ۦ tYq=(km!Pz!?i X |n¯ݓQOY m1@Hl |V=8P?!'DOW"p6O|`gř?-^{19>ѺA.0ְ鐱ęڼ|߻<ƹJ}k0hqrG2k"-ȬWBYhNULP1@8O71 ƻ. 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2000 Adobe Systems Incorporated. All Rights Reserved. U.S. Patent Des. 337,604.Minion is either a registered trademark or a trademark of Adobe Systems Incorporated in the United States and/or other countries.Minion Pro RegularMinion Pro%i WZ5:`v22> % I  / 2 I o  # 3 p ~ U   D e !o#]emE %<Jeov~EMfjtFp|,S-AZ0=DK +^&7NQy(/S_dl 5Rk$=Valsz"'-@T_gos{    ) . > N ^ d n v ~ !! !!'!3!?!H!Q!Z!]!c!i!n!s!x!!!!!!!!!!!!!" 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EPXD!YY-, EiD` E}iD`-,*-,K &SX@Y &SX#!#Y &SX#!#Y &SX#!@#Y &SX%EPX#!#!%E#!#!Y!YD- ,KSXED!!Y-+++6+!+bF*+H8+!+0+!+qbF*+2T+?8+++ E}iD(Xf!Ms,FAGRH/I/Hи/B и /B и /Iܹ7Aj7z7]A 77)797I7Y7]79EX/>ۻ2$+$29$'и'/2-и-/<A<qA <rA!<<(<8<H<X<h<x<<<<<<<<<]A<<(<8<H<X<h<x<<<<<<<<q01%#".'#74>324.#"#"&5463232>54.#"326/B)!%O/:'D1"(B8\!   %!;&2:,J5 6ve3%(5&=!$hU&G7! %."!4M endstream endobj 83 0 obj <> endobj 618 0 obj <> endobj 619 0 obj <>stream %!PS-AdobeFont-1.0 %%This font is a conversion from Helvetica-BoldOblique with the following copyright notice: %Copyright (c) 1985, 1987, 1989, 1990 Adobe Systems Incorporated. All Rights Reserved.Helvetica is a trademark of Linotype AG and/or its subsidiaries. 11 dict begin /FontName /Helvetica-BoldOblique def /FontType 1 def /FontBBox {-166 -218 1114 770} readonly def /FontMatrix [0.001 0 0 0.001 0 0] readonly def /PaintType 0 def /FontInfo 8 dict dup begin /FullName (Helvetica-BoldOblique) readonly def /BaseFontName (Helvetica-BoldOblique) def /Notice (Copyright \(c\) 1985, 1987, 1989, 1990 Adobe Systems Incorporated. All Rights Reserved.Helvetica is a trademark of Linotype AG and/or its subsidiaries.) readonly def end def /Encoding 256 array 0 1 255 {1 index exch /.notdef put} for dup 32 /space put dup 33 /exclam put dup 34 /quotedbl put dup 35 /numbersign put dup 36 /dollar put dup 37 /percent put dup 38 /ampersand put dup 39 /quoteright put dup 40 /parenleft put dup 41 /parenright put dup 42 /asterisk put dup 43 /plus put dup 44 /comma put dup 45 /hyphen put dup 46 /period put dup 47 /slash put dup 48 /zero put dup 49 /one put dup 50 /two put dup 51 /three put dup 52 /four put dup 53 /five put dup 54 /six put dup 55 /seven put dup 56 /eight put dup 57 /nine put dup 58 /colon put dup 59 /semicolon put dup 60 /less put dup 61 /equal put dup 62 /greater put dup 63 /question put dup 64 /at put dup 65 /A put dup 66 /B put dup 67 /C put dup 68 /D put dup 69 /E put dup 70 /F put dup 71 /G put dup 72 /H put dup 73 /I put dup 74 /J put dup 75 /K put dup 76 /L put dup 77 /M put dup 78 /N put dup 79 /O put dup 80 /P put dup 81 /Q put dup 82 /R put dup 83 /S put dup 84 /T put dup 85 /U put dup 86 /V put dup 87 /W put dup 88 /X put dup 89 /Y put dup 90 /Z put dup 91 /bracketleft put dup 92 /backslash put dup 93 /bracketright put dup 94 /asciicircum put dup 95 /underscore put dup 96 /quoteleft put dup 97 /a put dup 98 /b put dup 99 /c put dup 100 /d put dup 101 /e put dup 102 /f put dup 103 /g put dup 104 /h put dup 105 /i put dup 106 /j put dup 107 /k put dup 108 /l put dup 109 /m put dup 110 /n put dup 111 /o put dup 112 /p put dup 113 /q put dup 114 /r put dup 115 /s put dup 116 /t put dup 117 /u put dup 118 /v put dup 119 /w put dup 120 /x put dup 121 /y put dup 122 /z put dup 123 /braceleft put dup 124 /bar put dup 125 /braceright put dup 126 /asciitilde put dup 161 /exclamdown put dup 162 /cent put dup 163 /sterling put dup 164 /fraction put dup 165 /yen put dup 166 /florin put dup 167 /section put dup 168 /currency put dup 169 /quotesingle put dup 170 /quotedblleft put dup 171 /guillemotleft put dup 172 /guilsinglleft put dup 173 /guilsinglright put dup 174 /fi put dup 175 /fl put dup 177 /endash put dup 178 /dagger put dup 179 /daggerdbl put dup 180 /periodcentered put dup 182 /paragraph put dup 183 /bullet put dup 184 /quotesinglbase put dup 185 /quotedblbase put dup 186 /quotedblright put dup 187 /guillemotright put dup 188 /ellipsis put dup 189 /perthousand put dup 191 /questiondown put dup 193 /grave put dup 194 /acute put dup 195 /circumflex put dup 196 /tilde put dup 197 /macron put dup 198 /breve put dup 199 /dotaccent put dup 200 /dieresis put dup 202 /ring put dup 203 /cedilla put dup 205 /hungarumlaut put dup 206 /ogonek put dup 207 /caron put dup 208 /emdash put dup 225 /AE put dup 227 /ordfeminine put dup 232 /Lslash put dup 233 /Oslash put dup 234 /OE put dup 235 /ordmasculine put dup 241 /ae put dup 245 /dotlessi put dup 248 /lslash put dup 249 /oslash put dup 250 /oe put dup 251 /germandbls put readonly def currentdict end currentfile eexec M#1H5 J6o \&rtS(#v\0\޹V7Fe༙OYx5-cY9^%Y6 (efIOldN"wȰ;)UƽoFg/rvV$JS8_oc@  o9-eGJp}[Do]mN=4*{ܯq=eU^t6¤)w Rfxpc @X$UČc@:p:20eַl&^ ZXs/ 1/eP6hJ/ A&;Mg*JIWCz5*E)X3l]|44R\ΙU~d 46 ^g1rd͂_LSg%[JedA )AdM f?i8֦1 r=Er PP0~y9ATcs%ak.Hl fsVY]KEЂ 0'/^{>E^ 2u-`r^9noT+ꜮxjpA3̕Xf~utJ I͇=47~>K=ڞ_`6p6^C N>3~OA73-pqNn Lo\%q^|ý㭤ro,B)/TgH#R#K/p_ӿ7EO"w Pe4.43j̼¬`Fi(!gR;.H`:֢t L$xu5*u}NkBa^}Z$H_{HnQMj'E6eN0T݃X Ș=fJ pr$Z gf?_6{Lvp=K!6rFCq0$aM{¼EofsP% #ܝ百 y,9SR{P*:QqYьDjLj,ZˠR; 㲣bsg@Rf>M}g>82pB.zu1J+%0{ykC;w,.IIֹ=B`az-V5Nd7^RYHwJ8+?R3BJ!Q it=!"n_Ảd/2xˏJV2?iTդSٜ3]s4K?2Fw&ġdy_XLjtCZmP8!%ʎv4Hgi9I<7lmu{!ّ]fʚq?\8Y7+7H#Q-@XƽAg2]#̹W:฽4Ƥ~٘&VX|q1rD% cX?6u;"YNt>}cPt }f2i hOTVb0s ȴm$c@#24 x]܈?*TpG=7zzZIAO*\H`7ŀN3`g%>§LI-aSiaTM|fL4:oIvif \w!paZjI:ykB="[Օu7&xtu|d\ 7 1I!{uLt´6Bqn!^H7ڷqMADi D?&I/ ѥ,)Q5Z+O~MxW^veh~J-&ƀc>g6dsb_r"vb`7vk]c*t]%p`XA `zC;^ ;HoODTܕC\v/;Sdyp8ۥ{/7v͋C{Sx{zf^ ;:2.l.l a|.-kz⭆1qBݺqU?DŽ)2-< fyMN+B:$wܢ!fDGݎ ]lm"3;"Y`"hDGbD 1zh!sqGNh<22ٵsFLR'q.H\0KTs n K ƹ2;0Qݘ[J8rcoOwf5ΤDO吺#P~P Iߜ%Wv&n(2&!P;7+Y-ئN<ˊX8S(5 ,?rCE?Mߍfok+@lH0<7>6Oʰ)04?< '3`S('_=Џ9C}?<њC[MJׅ+i)_(AgTɿ)[Ia᥎O)%cef_Bc1֘/iOQm32'5ssmJ ѡfYs!eg'@NLfWwQG 2SbY| NnQzoXw*})g'U>['Ah_y_w粢f^ -8=1O+ f:J 3L"S|HBkIbC8E֛q&YF"Z<<8lNY"W@4}'^cez d^'R/V |1L=rug{xJوmtP GG7IUv tҁBC:3 %6%ASN0$"AHΩTޔLl0jN+mb3pZ+k3˞~˪0eJ ӝ82Ƹm);nzY,l0J{JfؕqYr3/oA쫜$`7Z@ca; > N QeGr.v͚G37ZRIϥ_:fמƑx|= wo &P/sW,TOQmYLޭqK /s",xi5tRE1Z mTdQ=_`JmPRd?,;xrO]ՌZ(ba]ۈ (3p0ze'uu zfo) ؂3jHm`xb"OPL$VGdU nb1ͤΦ";FLW2cZ lZ{E ?m4npq^!8 @㓴E~&M,zE2sM;M0CUe[7]7l%)* U@&IP6l'`p oqbٖɟiSD\+ uW6/<(u\FYRj%K• VJN=O$܋@nN&d\;2m_D+0 -hxqYRJr6R +:RSN獿Ym00(^N%G,;pc J46LbjZ`'[X*sj4*Fb|ZP&8nJl]lwxm%ª"&Z]OŒEED$J "8YvA? _sZkCDQdU6}T.J"LST҇gSqCbg2:!8 nH Vz$k  1 OPkAќE7q2^;xq'D+3VbؗNb}._#()T<2n = ǽ cJAtME[g*ɇt@T(DqDˏ {~ƾ, 2O"kC_>~')%<qJc-FV;GbEL6@]=Z=n`4AR/pAh౔La"Z>_5fAֹ@|M 7XHڛo8DgXADbK ZՆ)5%o:i\2{/OW1ec9$ކq=_$#@ب0\Um'`jVߕ'߁B} :z:qhZUvZqb> /jfETeihJZ0Γ1Gyҧ1"FyN96_/C3.im UЁIN!&NH?M&%-YD⚞J+d^nI;)B<~v9Q[ywhu~kaݍ6͚:{>f(-;"?OqBΉ@?4BJUKg/l䚶H8c}[+) RMjwyA$Cڱ4Ќ$[2ZBס/B%Yvh ? 3wNIi7A !UH= nR'>b R=Q7g] w(1 B ΋*x4r-c DG(qg-\w'*m^lhr W@HOw_d'L3pi#x>4wka> [U2}WQv}03-gRR7ۚҤTIgdJ8oK݊s4׶k^E$犜npAh౔L, u[amǔ9ŌA@>5Ƿ8u>֋ 'Saܴu<~$WrHԀ<tYV! -Ir掞kt!-3MHg{۶*; \;h;!˶7ҳfqD&\ݮ9LSS^Lq KAsRly˻9k* P2й0$oN@ŏRrճj4 D% 8K&*y蔨v+ILf+PR]:0ʏ 8^؄j C=,(;e]-5JZYSvEt`2vsMTF Or@) ` &Jm+|#K9 lo`g꿜ܹA\9pŪhSsuL[Jm~֎q $p[yGcw1gEb"d;e?rmW"By׏%@+oZZENkօIlنȲU`oec=y_xVJ*/9E ;)OcsSh"Θ[ sG9[--qFfc =LgCc9ia4\0+a-#k x3ɼ^o|yu N7ߟASt%n)Ot݇Z) s[/97G4ȚלknroM2F 0 .{Ѻ mQs?.3D#j?sXϝg 9g] !4CqIgpG9smtFx9a!b(UUBSu+<[(Iwj~i%RqJyE@3T[d_Xٱ@+~H𝇵3/w?Q $ƖT,ÁB.ERHn*Iʀ$RbITm*Ttb"Qj֎E9 58POUe$莹u&>. 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Xbq>W+t-/$GlFՓ\vH !j\ n9_V #AZDd@|,QFYKyqͲ8P^}@8Ǣy4=/J0hy7_5k.vaLNn[ z\_Us=ʱoB5D{ZW/?0[tӏnڝF~X%K)o-y&[ E%^=##~7-. !61-S(TxKjƑYcdK, F0/tz(I fO:kc|B)ozĆП[qZ/ݩz 6rj._~^B`LcI6u޳z;H$( ͟uå1:tP ANLDGܔ:74r9D( tz /3G8[>WP*{,|R Ⳃ@t8O_ -hF890n@oMIvm C 22cM)0k+0s 0XG\ UTqU?ˤn3Jz">F4/Y SO(E4U6eYRPo_ u<ofZZX 仟:SJFS0V|R1J!0RK9U_ QEg뼤G5{F$臍4J9`\́~d h{9-[5'eIn4/9"P>B~.鵄=87^x0mJ.o&tӰf=XDt5H"46)YyJut>d"sz$gS$8pP)Y% #0˱bY0dYkc:$wXU&cĝF^H^F+#m(n%!5H݀QKLJ_N<T+ҨQ&lؾ݂Ѓ+\lz}7 ^ J#QPCr]e]{팺~"/7i͞Uy/ 纒Tke+09'FoDݘi*d)&?&^[^VqǭdžOF/zJZ2]Y Ã^ ld(owv⭞΅{[ZmaFBٲC[OȒՋ#h7Qh%Xo!ѶN*o2ˎբy86Vm;R\QhB[w!a[[Y{cŔ L٧!3xxpnRɃrEWˆ3m=,irwU?H7v!@拗)}I㌅9@qCGZNft; 7\Î jp5YB"FByZ|s6,(a@ߘ“B/ePwc)W35?.%;(m6>7JajZԱ5I>#*Ҫh89$<mm#`N(rPrAO:q:ݟFA)r1,³`ɹ:NGsmUSՍ7 ^ͷ<̻\m:Td}C?!0"l5fMh+ "WQ} 浐8@-epq4n X @}xiXWÅbV/1ϖT%=l BjՉ&@ Q6w;@7X^fn:úMݩBQPeGa]ޠ0 (^V Tg%kz/,^jTu<,Ǎq[U+iMBH3jϺRIc7?S=76D{S\:Η ܤ¦-V̺!ʅznux%DiɢyUGkbOB2iAyx z﬈H LMوa@wra UrZE]^>rc8;쥍iWbjSp߼[A\wKT(fhc3O8y~y'x}Gge戝?WM:uj6+\Ohѭ>ra'wG;n6;wLlC̙M$zc񞀎cŋI06S%U(F)iBa%-%wei & W[D]7dUGh1@FXӁzM[I6ÍA,*S,f9IOfcSLvk|) jᘮOЛR{`l$:9t_M-A,mXh+}e.g[vg9L0N)O`T]/qc\&ަ:\ mL8DE2qۉGl95^i^1ZHnXU5}2`BȃL=SGJ\r L]׈ܤiۢOHb9Gê%4]ҥ} 9؉ KB Z2kl؜QV VQއLd)_sm N9@G`N=} 4 ѿ84#h{}8^'BX.ߌk Yq#gJnj0Wѥc!k =M-X4lq-Ar#i{iX;0Eʪ(=qQųAĶ г v~2^DYö$&.b 9F#0SEf_pRZV88hxu ӯFgCpLcTz&Lٙ]e1=)Ba^| oRͬ<'W :}@ 4@5j.{좥 My*v/Y;!< +$"'~B"7̢ыu(-}"&6qsB\>ҫ<1{j8Fd51+*nyEcAGS4x2JNgRص⎊}ޞK/۵!RzC$"CjƂ͑?M- >di jrR8 :k jSWI4N_/6'!VLr')5DY;!Lnyh(욣J1tZ})FcQk^AL,4=);|F`[0000000000000000000000000000000000000000000000000000000000000000 0000000000000000000000000000000000000000000000000000000000000000 0000000000000000000000000000000000000000000000000000000000000000 0000000000000000000000000000000000000000000000000000000000000000 0000000000000000000000000000000000000000000000000000000000000000 0000000000000000000000000000000000000000000000000000000000000000 0000000000000000000000000000000000000000000000000000000000000000 cleartomark endstream endobj 85 0 obj [/ICCBased 620 0 R] endobj 620 0 obj <>stream xwTSϽ7PkhRH H.*1 J"6DTpDQ2(C"QDqpId߼y͛~kg}ֺLX Xňg` lpBF|،l *?Y"1P\8=W%Oɘ4M0J"Y2Vs,[|e92<se'9`2&ctI@o|N6(.sSdl-c(2-yH_/XZ.$&\SM07#1ؙYrfYym";8980m-m(]v^DW~ emi]P`/u}q|^R,g+\Kk)/C_|Rax8t1C^7nfzDp 柇u$/ED˦L L[B@ٹЖX!@~(* {d+} G͋љς}WL$cGD2QZ4 E@@A(q`1D `'u46ptc48.`R0) @Rt CXCP%CBH@Rf[(t CQhz#0 Zl`O828.p|O×X ?:0FBx$ !i@ڐH[EE1PL ⢖V6QP>U(j MFkt,:.FW8c1L&ӎ9ƌaX: rbl1 {{{;}#tp8_\8"E.,X%%щ1-9Ҁ.ǒ/O$&'=ޞxǥ{=Vs\x ‰N柜>ucKz=s/ol|ϝ?y ^d]ps~:;/;]7|WpQoH!ɻVsnYs}ҽ~4] =>=:`;cܱ'?e~!ańD#G&}'/?^xI֓?+\wx20;5\ӯ_etWf^Qs-mw3+?~O~ endstream endobj 285 0 obj <> endobj 621 0 obj <> endobj 622 0 obj <>stream %!PS-AdobeFont-1.0 %%This font is a conversion from MinionPro-Bold with the following copyright notice: %\050c\051 2000, 2002 Adobe Systems Incorporated. All Rights Reserved. U.S. Patent Des. 337,604. Other patents pending. 11 dict begin /FontName /MinionPro-Bold def /FontType 1 def /FontBBox {-125 -239 1052 750} readonly def /FontMatrix [0.001 0 0 0.001 0 0] readonly def /PaintType 0 def /FontInfo 8 dict dup begin /FullName (MinionPro-Bold) readonly def /BaseFontName (MinionPro-Bold) def /Notice (\\050c\\051 2000, 2002 Adobe Systems Incorporated. All Rights Reserved. U.S. Patent Des. 337,604. Other patents pending.) readonly def end def /Encoding 256 array 0 1 255 {1 index exch /.notdef put} for dup 32 /space put dup 33 /exclam put dup 34 /quotedbl put dup 35 /numbersign put dup 36 /dollar put dup 37 /percent put dup 38 /ampersand put dup 39 /quoteright put dup 40 /parenleft put dup 41 /parenright put dup 42 /asterisk put dup 43 /plus put dup 44 /comma put dup 45 /hyphen put dup 46 /period put dup 47 /slash put dup 48 /zero put dup 49 /one put dup 50 /two put dup 51 /three put dup 52 /four put dup 53 /five put dup 54 /six put dup 55 /seven put dup 56 /eight put dup 57 /nine put dup 58 /colon put dup 59 /semicolon put dup 60 /less put dup 61 /equal put dup 62 /greater put dup 63 /question put dup 64 /at put dup 65 /A put dup 66 /B put dup 67 /C put dup 68 /D put dup 69 /E put dup 70 /F put dup 71 /G put dup 72 /H put dup 73 /I put dup 74 /J put dup 75 /K put dup 76 /L put dup 77 /M put dup 78 /N put dup 79 /O put dup 80 /P put dup 81 /Q put dup 82 /R put dup 83 /S put dup 84 /T put dup 85 /U put dup 86 /V put dup 87 /W put dup 88 /X put dup 89 /Y put dup 90 /Z put dup 91 /bracketleft put dup 92 /backslash put dup 93 /bracketright put dup 94 /asciicircum put dup 95 /underscore put dup 96 /quoteleft put dup 97 /a put dup 98 /b put dup 99 /c put dup 100 /d put dup 101 /e put dup 102 /f put dup 103 /g put dup 104 /h put dup 105 /i put dup 106 /j put dup 107 /k put dup 108 /l put dup 109 /m put dup 110 /n put dup 111 /o put dup 112 /p put dup 113 /q put dup 114 /r put dup 115 /s put dup 116 /t put dup 117 /u put dup 118 /v put dup 119 /w put dup 120 /x put dup 121 /y put dup 122 /z put dup 123 /braceleft put dup 124 /bar put dup 125 /braceright put dup 126 /asciitilde put dup 127 /Euro put dup 132 /Eth put dup 133 /eth put dup 134 /Thorn put dup 135 /thorn put dup 136 /onequarter put dup 137 /onehalf put dup 139 /plusminus put dup 161 /exclamdown put dup 162 /cent put dup 163 /sterling put dup 164 /fraction put dup 165 /yen put dup 166 /florin put dup 167 /section put dup 168 /currency put dup 169 /quotesingle put dup 170 /quotedblleft put dup 171 /guillemotleft put dup 172 /guilsinglleft put dup 173 /guilsinglright put dup 177 /endash put dup 178 /dagger put dup 179 /daggerdbl put dup 180 /periodcentered put dup 182 /paragraph put dup 183 /bullet put dup 184 /quotesinglbase put dup 185 /quotedblbase put dup 186 /quotedblright put dup 187 /guillemotright put dup 188 /ellipsis put dup 189 /perthousand put dup 191 /questiondown put dup 193 /grave put dup 194 /acute put dup 195 /circumflex put dup 196 /tilde put dup 197 /macron put dup 198 /breve put dup 199 /dotaccent put dup 200 /dieresis put dup 202 /ring put dup 203 /cedilla put dup 205 /hungarumlaut put dup 206 /ogonek put dup 207 /caron put dup 208 /emdash put dup 225 /AE put dup 227 /ordfeminine put dup 232 /Lslash put dup 233 /Oslash put dup 234 /OE put dup 235 /ordmasculine put dup 241 /ae put dup 245 /dotlessi put dup 248 /lslash put dup 249 /oslash put dup 250 /oe put dup 251 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0 R/Contents 777 0 R/TrimBox[0 0 612 792]>> endobj 4 0 obj [/PDF/ImageB/ImageC/ImageI/Text] endobj 5 0 obj <> endobj 778 0 obj <> endobj 779 0 obj <>stream %!PS-AdobeFont-1.0 %%This font is a conversion from Helvetica with the following copyright notice: %Copyright (c) 1985, 1987, 1989, 1990, 1997, 1998, 1999 Adobe Systems Incorporated. All Rights Reserved.Helvetica is a trademark of Linotype-Hell AG and/or its subsidiaries. 11 dict begin /FontName /Helvetica def /FontType 1 def /FontBBox {-156 -218 1000 770} readonly def /FontMatrix [0.001 0 0 0.001 0 0] readonly def /PaintType 0 def /FontInfo 8 dict dup begin /FullName (Helvetica) readonly def /BaseFontName (Helvetica) def /Notice (Copyright \(c\) 1985, 1987, 1989, 1990, 1997, 1998, 1999 Adobe Systems Incorporated. All Rights Reserved.Helvetica is a trademark of Linotype-Hell AG and/or its subsidiaries.) readonly def end def /Encoding 256 array 0 1 255 {1 index exch /.notdef put} for dup 32 /space put dup 33 /exclam put dup 34 /quotedbl put dup 35 /numbersign put dup 36 /dollar put dup 37 /percent put dup 38 /ampersand put dup 39 /quoteright put dup 40 /parenleft put dup 41 /parenright put dup 42 /asterisk put dup 43 /plus put dup 44 /comma put dup 45 /hyphen put dup 46 /period put dup 47 /slash put dup 48 /zero put dup 49 /one put dup 50 /two put dup 51 /three put dup 52 /four put dup 53 /five put dup 54 /six put dup 55 /seven put dup 56 /eight put dup 57 /nine put dup 58 /colon put dup 59 /semicolon put dup 60 /less put dup 61 /equal put dup 62 /greater put dup 63 /question put dup 64 /at put dup 65 /A put dup 66 /B put dup 67 /C put dup 68 /D put dup 69 /E put dup 70 /F put dup 71 /G put dup 72 /H put dup 73 /I put dup 74 /J put dup 75 /K put dup 76 /L put dup 77 /M put dup 78 /N put dup 79 /O put dup 80 /P put dup 81 /Q put dup 82 /R put dup 83 /S put dup 84 /T put dup 85 /U put dup 86 /V put dup 87 /W put dup 88 /X put dup 89 /Y put dup 90 /Z put dup 91 /bracketleft put dup 92 /backslash put dup 93 /bracketright put dup 94 /asciicircum put dup 95 /underscore put dup 96 /quoteleft put dup 97 /a put dup 98 /b put dup 99 /c put dup 100 /d put dup 101 /e put dup 102 /f put dup 103 /g put dup 104 /h put dup 105 /i put dup 106 /j put dup 107 /k put dup 108 /l put dup 109 /m put dup 110 /n put dup 111 /o put dup 112 /p put dup 113 /q put dup 114 /r put dup 115 /s put dup 116 /t put dup 117 /u put dup 118 /v put dup 119 /w put dup 120 /x put dup 121 /y put dup 122 /z put dup 123 /braceleft put dup 124 /bar put dup 125 /braceright put dup 126 /asciitilde put dup 161 /exclamdown put dup 162 /cent put dup 163 /sterling put dup 164 /fraction put dup 165 /yen put dup 166 /florin put dup 167 /section put dup 168 /currency put dup 169 /quotesingle put dup 170 /quotedblleft put dup 171 /guillemotleft put dup 172 /guilsinglleft put dup 173 /guilsinglright put dup 174 /fi put dup 175 /fl put dup 177 /endash put dup 178 /dagger put dup 179 /daggerdbl put dup 180 /periodcentered put dup 182 /paragraph put dup 183 /bullet put dup 184 /quotesinglbase put dup 185 /quotedblbase put dup 186 /quotedblright put dup 187 /guillemotright put dup 188 /ellipsis put dup 189 /perthousand put dup 191 /questiondown put dup 193 /grave put dup 194 /acute put dup 195 /circumflex put dup 196 /tilde put dup 197 /macron put dup 198 /breve put dup 199 /dotaccent put dup 200 /dieresis put dup 202 /ring put dup 203 /cedilla put dup 205 /hungarumlaut put dup 206 /ogonek put dup 207 /caron put dup 208 /emdash put dup 225 /AE put dup 227 /ordfeminine put dup 232 /Lslash put dup 233 /Oslash put dup 234 /OE put dup 235 /ordmasculine put dup 241 /ae put dup 245 /dotlessi put dup 248 /lslash put dup 249 /oslash put dup 250 /oe put dup 251 /germandbls put readonly def currentdict end currentfile eexec M#1H5 J6o \&rtS(#v\0\޹V7Fe༙OYx5-cY9^%Y6 (efIOldN"wȰ;)UƽoFg/rvV$JS8_oc@  o9-eGJp}[Do]mN=4*{ܯq=eU^t6¤)w Rfxpc @X$UČc@:p:20eַl&^ ZXs/ 1&Kk; C^AW;sdhB %0Ƚ.TALūSfW(/`k{T V6T?p*7 bBhJ2E%p (+R⪻Yt+r' 9t'#N/[MXD5s s^AAo^aj-}gCĢQұs=Y)JW3SYR}4xY~ީۘjYɰı-˰rۢ[(/ɒ2ް# <:-fzbF,+~k Ead2^4i49X` W%ou@mVN5z4`L .%Fg!<7!/;:J듍a vHLK@u|u^?MHW <^BmZ4Ww#æs[ T^}CԢvyn^%*pTz$wK:W.z&Ύe;/ͻ|-]jT䎋4Ϲ- 9_8*8ۙ?Dw[ߦpH"@@ xJ_Oi;P2'Rк^*CVmHIx_2ρ"XI0,emB2AEvkD| ,O$ Lh3B#Vl''CImF &Zly1)~7!G ' q \m kvQ^f&KDnpH,:j ؜m t+ZzF??֍wL]BfguSEE<]*E@..$@t$6ڃ1mP|?T3VPߙˣ@Pܠ[Yٕҟf6mZR%#6P?1|}%qaBo*M*mpM3s@]c*utR 0`|pKߴE:h.YpmǍe1# !c/H+²|:.3Lҽ\)oBAVseu8+Ao'QӝmeN#/h ewǤMϓscHmVӅXN,8X$;䪓 D:lٸ'N› T ĭRB`4\TxwUgkgl#fK,{s +!v 7SP Jċoڶݞ xw EɈTh-+m^ذYa??1xҷ3kؠVlzn/0*F| qHb 빡{Y!"zy;S=Á^հɎDZ#dvVLs=mY5muQH^a !SZndHx`f-Ў\0w7ۧI lnPqlf&؇vB i%iMJNc(W$aq@(gw8p./-)WB5$?"2pP֠M\rWNVӻ9Lcs(9*&(9U;ZTD-Gd-zЯ?Ss/S}',6njԊXc5v=A]WGz 'Pӆ%fEsb6@Pj.;9k Z KN#vdJ#bDb^ LNJ W#Z3fIJf;T`lSyItf-';f hAu;V F9#D@ AJא'$]{L찕oU0-et]n/pH$ƺі*WCsr;Յv끦vAӷBTS|>VfG¿A;Y%eǪw%w}-HR' `>-'6mZ8rN􂲎Mtj\?n)HPB3/nUݳyS~yݣǿ#-Ww? ArK$3.$ [0V 'qB'foi :ZSA/EM?bf#ΤyI:`Hi9LQ.A* p-yF{g?Juc)3+d#>w΀gF7F4+rCE"oO#ܝ-oAX)@%SXǯbRrR YFjÔ.XredY/%D9^dRhIFjv@!G^ZqpvULCrsh9HW)6OX[Ƈ4`UŰݮw2ǞHI7t F8>АpsKL 7Bf;˱uUϟaN6.j2x"qfJNm5gic~׵& .DaV2Ů Ů&(Цzr f%*Цٰ]ς=01ACX#){VCl Icyx`T:=E 3d8l&9cjÐ5GĻ~K;'JٛK`1ӠAcrC(4Hѐ0!<H5gT=iJ vt|ԸSgl=l T䋨9YSR0ШRJ]K;͔huX6!t\UyN$$=_Sq#]3 Y:DLꜢY|΃*Wggz+8M%%)'6ҋzҧۯQ^V Gӂ6FavU9f}m9&B?gƒ=/Qj %Q=axE^C@l$+I)<|c+Z䟮`MZ#J-sJq~uU^"|' Ծu;*' 2{J%\W>tԽrCji0p55TtTogI^p%nȊVXYi~o3 ͛f]i)69n-W՝ѻS4p.ܺ\)=oyr7Й'mG(uOZoOά=؝ !as Lki`@a62C  M ,2R$[̐;oN&V{ĵɟ:|xTSh0QFU€0.z^$>5Ƣ dQ EpovYBUy FT" ,7|/ic;9M;GʏPEHphߘY'mpʞ? NP|iU!%m 77U&>FUCNT+Ƿ ݴv\Ɛ&:;h3DKaLeb& !ZWa%Xs,'WkaUV 瀦Zms: ndlIC#ckYHvOǙ)w05mSpEͶhGuc e!E˺r_e99% 8b]F׽n!.4ڎZғg|t7d@дI6I/2SU"{gybC̾4lz"1T =V榏Ǻk\nI_"ʌSTEldv qfıiroAG]ٓ7dOϿ n|{`'W">C5]>oIgz3"5* J]H|VPߴgKk%A/P)!&^z4մ}`sLΟ: ejES('gLi,M)c žt52? F.͛N¶LMCƢ[*D 3́vWO.Eƾ.j=71V/*rL %޽4گ|5w63 L.aD2/9 ˫o)V m]K[}b")l \g8VqIf.1]U-#4Fst5:1m hyzi.R {2^A&bjj-eyTZoV`@NK 6^*/҅zFC旱LS|bNuӳѣQ X9ԏ 6vQDa1"Iɑ;J'i{f _v|X! 7PoS9l/ qgpRo, ,w_4t0IMYRb[{y&,c;[ 7A-iy #BG I3k"c9o=8R>^_ವxҴ?%Ķ᳾鶣!ٲ鳾S|Ө?ĉ<鿓_ +ID~z:{( QpOi&qS|5RdCqzI->ꁰ d@=w!QU ;[Ruhpꯤ1R3molXrpŽM:F3VnZszJ| M24ߑ(Йbw4ߓԜRvffa;pI߼-~ҡoVDO.͊PR^kA^F|dž=.B㾕d- )-m/4,vWH@Us:};qxCAqNj!_%*Rd[lO꛴FOʁ"xvҼÄFW~ ,]aU;ltR!q;)V5{44rnvpONiQPYm uq6\} UUW MsF=>} Ne'gCaC=Ux|yAILܫ?2mE4:uA C4nǩ(Brmɵn2fA5gBk1(GZwdI[@yb:C]|-I9 Ήܱ[\ɭ E:c6@8U"`x9/G}h1Velievc nj9*՛`tVR 9 `_Q1pQ0bzfP|2Jh"w35!۪, ۗF=*suOL S Lq+\`Ʊڍ j&G1 ɪZ$Dبf`EeFFeL8*Ұ6*RE>'Ede>{ 0quPw/zݨ֋Ky|{).HB3*ɖ8v@,$J1d5VMv:Xc-}<% h^Pڏ*STNBq|@>H5;ݪ$4dL9>8<+<2g)b؉V^:F1&XEcfփa$bX ga C88:rw6*AP]Dj3 "zw#d$m'3֥_ϤvC{GOA1`_TcyO3[a:Kb^D.4sb6`"Pe[WhTE$+TCJlyaLu=u{[kjWV-VMRe WVKmW=J\䦞[D=)K?256I/b-Gˑ 29>ш7tL7ZYM8vϓ)zUV4"7g%H5f|$$:XXɠ/n DY=ع5DC8gm%^U>V.|dq[` &gN+8a D6MI/Kq:Q=Q "xNN f5'eyqF8D~5Aȇkqϡv|ͬUÓ,l7%Ǽe!7j|xC ]@%W0 ^t oveK` 35™6t'ϫqJr/69?`la3 J|e.%W=셼&a(/O>UpC b7R#߅|_j[;fղ{HTY,{ސ=}@Q˯E63lyI, u_h;]2 (*||B3 h<btZ4CO=e`jCrYu8ăNv=L$|і6x oK%nz߇.:9R`aJ$\][@u% y'\"m^#:Cҏ">b̤8_kmj ]P?uJP>M)# NXp%0Eh~\ kƴw):YBZU gJZf'G +%G=Żۉnq Af1>Y^een*y`=w&󆘔 GC[_[ÒuuE/?d}ߌR,XWNJ_rp9BvKfV bBsrQ郩N&ߨ(8]Zoo|h.FzșpvSjAěXU{TgR Sd{t^ ,앾dYr@IhXo`ngvW/J$ܹ>U?OeI6 l35'Bgjrpa!|;ͲM \c d]V'ol'pmZfPϵZjRl:m콒YOкou'2R¯S@g%'D&6ӹ"ևx6M\٭oGU u;F*ZȮ8戟52(ncE*{6qxe.jo}9* цDթLTd0UX?QyRur/\ UJH`q.b`Wc>Sm?!0] L3|N%Iq`4q eR{@vc%بl zWtɋJK _O,b@Wuu2jK̮" ڏ@oLٌVz={#4#כ[ jeF f7k-TM +#d]v,4!L|[ i7b&X^3pso~m!Rk5NۆI5 ߺoؿp*hu^*o7h.{T?GSԀW6 ~8{TMedrsSȕN(.,#tY~| Jz Qc)/̂yk|hh@W[[vg@dEc?6U h[o[MT$IS) YH4N—&ۈ[{_y`s} \ j!azp6Ơۡ _Q*jc΂r%^ ag-6WgHCWޒP*L6\cdmRJ6OfB0 $1 jϨݲZ=YΚ&>76ãO.նФP7N<)T `Pc !k& hP;T!/y3s9h쌏^D2L]ģfky:mu̙*~'Y1Sفh+l׏fx"k}{~7&ruvVFqfGDSEM^@&T[ֽ{z}U7).Y+83S&">._rTVaZ4 և )d';)xiwNx]0K|Ҧw$8۽?슄6F+!2؛H9$#:jHՅ:b"ƞ~#b6ma]`0хe)AҷBv:X_n^@3Cփ]KX7u4E\…~?r R-o>ى N\4d}qmU E;s>˱f :z5ڿ!<{t1iݕk]!=SnM] !Ӱ,G!swr|?jVc7AꙮnMpΰ:BI ("h'F)6G"~M|P1D)\!!"^`sS(Y6KOXFzuZ'/@Piq CRΚWF>"r?`S=[zƉ z@W_-|ccPDJD Op_=4HM#iZ1wUEXS'1OD@ r+ ''g.f>\ 6f"in];K !\:j_Sw ]G9˾#]3dS[۰jvb?(3,|y]1^]bQCZa$4b'RJB+(s K4 anvT!w]R|w2vҗ6v*[ic5 M zfxSblU~AJpJ) r $Jo/<ȨY_`UZH8hw0 $a9*;ʸ=3*Ōbs8U6̲p2ⱷhŰ辱)(;۱K>?˨Z0Cٻ:=2<@1Ě)4Ux˶fj)S$$(8p٣TIr지L{!Nq.y*(y}wHë޶) 5}@-c)Q ^/WL|_;5ۯ㊕y?b{wB/9I@I8_[URT&Tf*ƮϒiMYO_,S.^\'O%ũOH!6=) a!'-9FwMAq7Z#P@HMLX U5Os̸<rY3*HLc#+[豗? dUǀCtX(bceq!v đ 56GiN8l+Z]B&5}ID8wK(mn l_0To_չMa8](Kq{.kzeOl#̏X}ԴqgS-8 gEI?K =iesǸ!|N%?G$GFk:d‚_/is8lisH,c~r@%8RgXu?jQ@Un넮ڐ{s/<]%e)kwaiv',Vgű ҅PG82q|F+G@Y !BabH|Pm ^ܨȟ 03~uF7L2JV(GP -쑹ɞ ϭpSikq D@ i>8' I!r,o;5 /K7qsP7q39'r_$?f!Ti̋7\C+RykƏ N,=#vfm^^&HTG(^jѝ0000000000000000000000000000000000000000000000000000000000000000 0000000000000000000000000000000000000000000000000000000000000000 0000000000000000000000000000000000000000000000000000000000000000 0000000000000000000000000000000000000000000000000000000000000000 0000000000000000000000000000000000000000000000000000000000000000 0000000000000000000000000000000000000000000000000000000000000000 0000000000000000000000000000000000000000000000000000000000000000 cleartomark endstream endobj 768 0 obj <> endobj 780 0 obj <> endobj 781 0 obj <>stream %!PS-AdobeFont-1.0 %%This font is a conversion from OpenSans with the following copyright notice: %Digitized data copyright \050c\051 2010-2011, Google Corporation. 11 dict begin /FontName /OpenSans def /FontType 1 def /FontBBox {-187 -239 1145 812} readonly def /FontMatrix [0.001 0 0 0.001 0 0] readonly def /PaintType 0 def /FontInfo 8 dict dup begin /FullName (OpenSans) readonly def /BaseFontName (OpenSans) def /Notice (Digitized data copyright \\050c\\051 2010-2011, Google Corporation.) readonly def end def /Encoding 256 array 0 1 255 {1 index exch /.notdef put} for dup 32 /space put dup 33 /exclam put dup 34 /quotedbl put dup 35 /numbersign put dup 36 /dollar put dup 37 /percent put dup 38 /ampersand put dup 39 /quoteright put dup 40 /parenleft put dup 41 /parenright put dup 42 /asterisk put dup 43 /plus put dup 44 /comma put dup 45 /hyphen put dup 46 /period put dup 47 /slash put dup 48 /zero put dup 49 /one put dup 50 /two put dup 51 /three put dup 52 /four put dup 53 /five put dup 54 /six put dup 55 /seven put dup 56 /eight put dup 57 /nine put dup 58 /colon put dup 59 /semicolon put dup 60 /less put dup 61 /equal put dup 62 /greater put dup 63 /question put dup 64 /at put dup 65 /A put dup 66 /B put dup 67 /C put dup 68 /D put dup 69 /E put dup 70 /F put dup 71 /G put dup 72 /H put dup 73 /I put dup 74 /J put dup 75 /K put dup 76 /L put dup 77 /M put dup 78 /N put dup 79 /O put dup 80 /P put dup 81 /Q put dup 82 /R put dup 83 /S put dup 84 /T put dup 85 /U put dup 86 /V put dup 87 /W put dup 88 /X put dup 89 /Y put dup 90 /Z put dup 91 /bracketleft put dup 92 /backslash put dup 93 /bracketright put dup 94 /asciicircum put dup 95 /underscore put dup 96 /quoteleft put dup 97 /a put dup 98 /b put dup 99 /c put dup 100 /d put dup 101 /e put dup 102 /f put dup 103 /g put dup 104 /h put dup 105 /i put dup 106 /j put dup 107 /k put dup 108 /l put dup 109 /m put dup 110 /n put dup 111 /o put dup 112 /p put dup 113 /q put dup 114 /r put dup 115 /s put dup 116 /t put dup 117 /u put dup 118 /v put dup 119 /w put dup 120 /x put dup 121 /y put dup 122 /z put dup 123 /braceleft put dup 124 /bar put dup 125 /braceright put dup 126 /asciitilde put dup 127 /Euro put dup 128 /ff put dup 132 /Eth put dup 133 /eth put dup 134 /Thorn put dup 135 /thorn put dup 136 /onequarter put dup 137 /onehalf put dup 139 /plusminus put dup 161 /exclamdown put dup 162 /cent put dup 163 /sterling put dup 164 /fraction put dup 165 /yen put dup 166 /florin put dup 167 /section put dup 168 /currency put dup 169 /quotesingle put dup 170 /quotedblleft put dup 171 /guillemotleft put dup 172 /guilsinglleft put dup 173 /guilsinglright put dup 177 /endash put dup 178 /dagger put dup 179 /daggerdbl put dup 180 /periodcentered put dup 182 /paragraph put dup 183 /bullet put dup 184 /quotesinglbase put dup 185 /quotedblbase put dup 186 /quotedblright put dup 187 /guillemotright put dup 188 /ellipsis put dup 189 /perthousand put dup 191 /questiondown put dup 193 /grave put dup 194 /acute put dup 195 /circumflex put dup 196 /tilde put dup 197 /macron put dup 198 /breve put dup 199 /dotaccent put dup 200 /dieresis put dup 202 /ring put dup 203 /cedilla put dup 205 /hungarumlaut put dup 206 /ogonek put dup 207 /caron put dup 208 /emdash put dup 225 /AE put dup 227 /ordfeminine put dup 232 /Lslash put dup 233 /Oslash put dup 234 /OE put dup 235 /ordmasculine put dup 241 /ae put dup 245 /dotlessi put dup 248 /lslash put dup 249 /oslash put dup 250 /oe put dup 251 /germandbls put readonly def currentdict end currentfile eexec M#1H5 J6o \&rtS(#v\0\޹V7Fe༙OYx5-cY9^%Y6 (efIOldN"wȰ;)UƽoFg/rvV$JS8_oc@  o9-eGJp}[Do]mN=4*{ܯq=eU^t6¤)pOp@GRƪDR;fa>1\!Bak [UR-5ŏݫaτU66 7 rT/34+6v)Xs"RV ֦ u0mև3d ,ڣ.Ϳߖ8/qz6۞{$FQ{eI{n]P:tkTml EYĕRyZ1\Esk!AC5n|XWҍPqX*?|h6}N@owa:^i+v`#xJwYjdld;F.m B}ؽ7m=gvK`a)"MBJ 6ה'Ir fӍ£t-?(I7EH8JB(g`Ѳ|P.y18 D|al(Q,"]:uT}-m~t,@ {WՑfP׍W{8/h89 džo8LnQ)n^0x 7uC l <3dZl)73e˥VdBE`c|CU}kE@z `(ʭN!֖֜!h"4$IXbZ䰨pʶ@P,Ci3<؍9yc,O7o>J.ޜt7 cJL3E^|p]NG?1Cօk;PYkf 9SfPF?p-it"@/7{?a33x%Az4T+XX/ k@LcMgx0B]]`W玐=A2j:/ g&ZY!,~%\OZy탒OSM{i݈_L09P >~Ţ?d{H߂ AB'чD #(QD{XlI6YX c, ~2|2h~- "G}@NWz \T['I Oe~8>V_cf&Aj [ /Yӝ4%H35pQhTDFO5N̐R\k+Hmǧ֫K0.b.*CP>0FW0CWͲu2[%^TkkTj)J*h  VW^g/_+%l]` OʥHU2Kʨ6]ڈ@gV1ą.'2c1e'(Ȕ.$Nk"h+KT5=S.e_ Z~ DP}8&"<$wx6eKGraV[ϥV>!w[xHٜ)upU*-ˆK~]^DFb/a .`7awAҡxtqk#q9DEq oWfqF_(D> D*rt DQa@Ej:: Ջ ?ΡH>@"1>sk2,g/U/(eEuR!HKM }:yG@YJ ɷr-M`T]&Wio8XjGzz(.ɝ{_-u9jWqs,"UKv  f7Q~*a\8Gp;AF-ƻ<1[gDAOG_\K%XO𛖹cy k}4[{_' w_}fȘ q'U9 `C jrY ¨ o*SUҵ*QϿ؉B ~!%Nofkx[$ޅAPn6:7V=gOXbP&RW x_mƇA WfFho^[f|CpT=wլ=_51])52|J*'xTִ!}u'fb&bV׿Pi &HtN=9] Aije 15jiTkHh`F92{Yh3"Z]tDxQ@*}! 8tյ+rYfigfDXKw"z*kۖ A<_s@sX|zS>}EzTLQ8QҾ( I6F1#1V ֱa͗T;#sn޼8V\04oWR_؀ !'B^fNj,D_ KrX={꯮:4l6]кOH^ߗf>x5^&DDfϖRϣ }#M5d,1S'_y(т; Z5ڟt. uR&[GJtT!D~Lz\W[%".Do7py?ay3PgМ "CEuއG  oE4 ݾQN4NUNl/%ݭ\cE={B/mK|#oFS -A p9 .WpRTXIְ1>񲹳ʡ;U@7Ĥ:9!"03!`8`ɱ6<|[WѾ{@G 7 ΈЁ. 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!z1fi5wZnm'5w)*skZx2j8^ g\S2B o*a$sҞAgAxi2XSp]~֖"_SJh]T <ÉăN6ՊA?7>/4?y: WP7ہ,=A?>0ucDȲ_D@QVVP dt(MW:>"l l tҾ6[7X<_Aj5ꀷhʴߴڞ0®50P#ݫ=mʟ}P밳W/LٱʶIJϡ˰8-ĵ:Ȇ<]P\ oyB5*+@A_GFiG^2tXlX}D_R ?FB0NӅAFf: F]>*$3,D$Wm8MC#뒧m"_^LBIq;;?/3:zxlUG5lnt*(Q Ivj(^ 4ᡝ4ͤ1 +"4xyDo!k LVwa}UsG!$>ϔ;³ݶnL<8S+6L'K-4jΦȲ0YZy#y0000000000000000000000000000000000000000000000000000000000000000 0000000000000000000000000000000000000000000000000000000000000000 0000000000000000000000000000000000000000000000000000000000000000 0000000000000000000000000000000000000000000000000000000000000000 0000000000000000000000000000000000000000000000000000000000000000 0000000000000000000000000000000000000000000000000000000000000000 0000000000000000000000000000000000000000000000000000000000000000 cleartomark endstream endobj 769 0 obj <> endobj 782 0 obj <> endobj 783 0 obj <>stream %!PS-AdobeFont-1.0 %%This font is a conversion from OpenSans-Italic with the following copyright notice: %Digitized data copyright \050c\051 2010-2011, Google Corporation. 11 dict begin /FontName /OpenSans-Italic def /FontType 1 def /FontBBox {-229 -239 1072 812} readonly def /FontMatrix [0.001 0 0 0.001 0 0] readonly def /PaintType 0 def /FontInfo 8 dict dup begin /FullName (OpenSans-Italic) readonly def /BaseFontName (OpenSans-Italic) def /Notice (Digitized data copyright \\050c\\051 2010-2011, Google Corporation.) readonly def end def /Encoding 256 array 0 1 255 {1 index exch /.notdef put} for dup 32 /space put dup 33 /exclam put dup 34 /quotedbl put dup 35 /numbersign put dup 36 /dollar put dup 37 /percent put dup 38 /ampersand put dup 39 /quoteright put dup 40 /parenleft put dup 41 /parenright put dup 42 /asterisk put dup 43 /plus put dup 44 /comma put dup 45 /hyphen put dup 46 /period put dup 47 /slash put dup 48 /zero put dup 49 /one put dup 50 /two put dup 51 /three put dup 52 /four put dup 53 /five put dup 54 /six put dup 55 /seven put dup 56 /eight put dup 57 /nine put dup 58 /colon put dup 59 /semicolon put dup 60 /less put dup 61 /equal put dup 62 /greater put dup 63 /question put dup 64 /at put dup 65 /A put dup 66 /B put dup 67 /C put dup 68 /D put dup 69 /E put dup 70 /F put dup 71 /G put dup 72 /H put dup 73 /I put dup 74 /J put dup 75 /K put dup 76 /L put dup 77 /M put dup 78 /N put dup 79 /O put dup 80 /P put dup 81 /Q put dup 82 /R put dup 83 /S put dup 84 /T put dup 85 /U put dup 86 /V put dup 87 /W put dup 88 /X put dup 89 /Y put dup 90 /Z put dup 91 /bracketleft put dup 92 /backslash put dup 93 /bracketright put dup 94 /asciicircum put dup 95 /underscore put dup 96 /quoteleft put dup 97 /a put dup 98 /b put dup 99 /c put dup 100 /d put dup 101 /e put dup 102 /f put dup 103 /g put dup 104 /h put dup 105 /i put dup 106 /j put dup 107 /k put dup 108 /l put dup 109 /m put dup 110 /n put dup 111 /o put dup 112 /p put dup 113 /q put dup 114 /r put dup 115 /s put dup 116 /t put dup 117 /u put dup 118 /v put dup 119 /w put dup 120 /x put dup 121 /y put dup 122 /z put dup 123 /braceleft put dup 124 /bar put dup 125 /braceright put dup 126 /asciitilde put dup 127 /Euro put dup 128 /ff put dup 132 /Eth put dup 133 /eth put dup 134 /Thorn put dup 135 /thorn put dup 136 /onequarter put dup 137 /onehalf put dup 139 /plusminus put dup 161 /exclamdown put dup 162 /cent put dup 163 /sterling put dup 164 /fraction put dup 165 /yen put dup 166 /florin put dup 167 /section put dup 168 /currency put dup 169 /quotesingle put dup 170 /quotedblleft put dup 171 /guillemotleft put dup 172 /guilsinglleft put dup 173 /guilsinglright put dup 177 /endash put dup 178 /dagger put dup 179 /daggerdbl put dup 180 /periodcentered put dup 182 /paragraph put dup 183 /bullet put dup 184 /quotesinglbase put dup 185 /quotedblbase put dup 186 /quotedblright put dup 187 /guillemotright put dup 188 /ellipsis put dup 189 /perthousand put dup 191 /questiondown put dup 193 /grave put dup 194 /acute put dup 195 /circumflex put dup 196 /tilde put dup 197 /macron put dup 198 /breve put dup 199 /dotaccent put dup 200 /dieresis put dup 202 /ring put dup 203 /cedilla put dup 205 /hungarumlaut put dup 206 /ogonek put dup 207 /caron put dup 208 /emdash put dup 225 /AE put dup 227 /ordfeminine put dup 232 /Lslash put dup 233 /Oslash put dup 234 /OE put dup 235 /ordmasculine put dup 241 /ae put dup 245 /dotlessi put dup 248 /lslash put dup 249 /oslash put dup 250 /oe put dup 251 /germandbls put readonly def currentdict end currentfile eexec M#1H5 J6o \&rtS(#v\0\޹V7Fe༙OYx5-cY9^%Y6 (efIOldN"wȰ;)UƽoFg/rvV$JS8_oc@  o9-eGJp}[Do]mN=4*{ܯq=eU^t6¤)pOp@GRƪDR;fa>1\!Bak [UR-5ŏݫaτU66.exC+LoRSh}gcJGbt0߇ʱUyuam8A,w-m op` ̩TDl%S֧)7\늩lv+.GKa9B VJ@EC#LS[b/ȜԸ 61 @5: SlV$mIy<(l|n:nhmI4 -4$mGYE'6]T95LώhV{(ޑG wֻÎ V0|}fc)t>ÙѵѵGZ:ɒ-&5})q'Ζ紳ԫAxU㾱|1hАų??Ƞ5:c'5ձѲӶؘ8(ϧ͓ȱ0)3k԰=6#7o淡6t"{neܸ"+91q6#<Ђl(fMU| e;>VGhOZE]ݪq Xv׬:}:xVXXߗLJ:+!#j-L\s̾t"]϶m^?K[WM-}6EiO UKJĬ;P 钤2¿_e q@, $ycdS/{L/\MpWN B(VƒKJ@f Yq~8љ%) 8|_2`;Sū1x>kΨC t{"IU> [s]{g)Ma|FSNǦ6 M1}@,',ņIomUc,Jk% ٬pg~b@yzF?r5uE_& hV&cU0Ea Ҿqs6ϋzc.gHՉ:BZ2vC7'&pqye47"ZOh]u>+S|ϜS&wKru^E*z1,&$G=N? 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KǴS*JX n{¨*3!<>ư#hԶzfiq~14kP+yLBtvå4=z~Vf>]csz54NSUOeXІc|n࣬Yr.nĐ$5?Eq#9p)HzaYF3F}kk2:1=D2 iDnL |8*1w#'J6\gFU{fu{]r! e8kAh4D iK7"jޣ1P,M#94j۰{]V: 2T"?i`K\'t4"m{|,1w3=䓷 xp5Q3_ys5dѕ\?{0ry~Vc38'Zqy |ǼA}MC F?;ZL&JƢ>͸RĒ|Ԏ-}ѮAj+=ӣ尪ָڳw7Θaf`Ԭ5:L>Wl汹"ԱѴQV6ٕ-8/7.>ݻX1#ċ0ڶ5(+a_%4錬ڱ-SА-Ņ20gUù6<KA)9g;2)1Awmk%0"\h#(As~1gc#cJtz1}}>"bD)-~VEBڪ6y1(Gk>}gjUEWv{:A^L>E L3|#qqLD~6tBOׄ/UeYM=kCYov;S()b)ǙT~wkUuADSm$..{?RL'ٜ4)gxK2nqv0_"Мh;ǩك[^(!&G/O_3B̨'?8ǣp^?fw/m}ىFԫ)ҞTZ C.[-1cLِE82TѲ_4$zb omm&gdy[ H{y5iI{{5fLbbzׄnQxE@ߛ-FF,H hA)Ϣ֤օ# 7ևv6:ޔ4%'گ&,8<^z*ڦ`V]2+.:VD'{ /O3QUP2R7?z>F<#!h:ۯ}`s˙pW^ lNm_ cSúY")e՞7 %|!bRcc7/9:towSV<_O1)V2*&R*o.̻A[_A$Xsj4*T @LҞ6`Eۅ#;cC`&)f CM4_k<%woV@pTt()V;nn&XX+lMlrp_TyÔ1{<]54k-He"'f\m+vk ǯHIEf XK=+(eD! c?ìxƟt_v;-^YA|^7!7Wכ=`32w]ښPJ鷷 -6V܊>7?Djp& ѣB >@z/rl3,x>]ګ1g*M ޣ܎L5@fo1 0G˅@8DFHٞZO1W%41-Zذp1|0=kp}X ҏs E'|yQŚ7SʾF Ƈ˦f3kslޖ30hlQAjB`q,x Nȯ{=VUv_Q< P@pIK=ݰ(*)T\r"*~(4(; /T G?ǽ< #'0R U!   %+,;'&\D](("OXd]:_]UWc) wk4˥Izopk@E3S2n^;\4 6#GQBTIjU4Bf%!NJfYpԔ..>Ċޢ<؄s*2f˗ [ 5]zmG0sFx#K(-;Xό,QK(cb6 Räy"X\fA{VVyXc8ZAu-؏i;wFl4ϑ@Q&_ƶIa} <(S> endobj 784 0 obj <> endobj 785 0 obj <>stream %!PS-AdobeFont-1.0 %%This font is a conversion from Helvetica-Bold with the following copyright notice: %Copyright (c) 1985, 1987, 1989, 1990, 1997, 1998, 1999 Adobe Systems Incorporated. All Rights Reserved.Helvetica is a trademark of Linotype-Hell AG and/or its subsidiaries. 11 dict begin /FontName /Helvetica-Bold def /FontType 1 def /FontBBox {-166 -218 1000 770} readonly def /FontMatrix [0.001 0 0 0.001 0 0] readonly def /PaintType 0 def /FontInfo 8 dict dup begin /FullName (Helvetica-Bold) readonly def /BaseFontName (Helvetica-Bold) def /Notice (Copyright \(c\) 1985, 1987, 1989, 1990, 1997, 1998, 1999 Adobe Systems Incorporated. All Rights Reserved.Helvetica is a trademark of Linotype-Hell AG and/or its subsidiaries.) readonly def end def /Encoding 256 array 0 1 255 {1 index exch /.notdef put} for dup 32 /space put dup 33 /exclam put dup 34 /quotedbl put dup 35 /numbersign put dup 36 /dollar put dup 37 /percent put dup 38 /ampersand put dup 39 /quoteright put dup 40 /parenleft put dup 41 /parenright put dup 42 /asterisk put dup 43 /plus put dup 44 /comma put dup 45 /hyphen put dup 46 /period put dup 47 /slash put dup 48 /zero put dup 49 /one put dup 50 /two put dup 51 /three put dup 52 /four put dup 53 /five put dup 54 /six put dup 55 /seven put dup 56 /eight put dup 57 /nine put dup 58 /colon put dup 59 /semicolon put dup 60 /less put dup 61 /equal put dup 62 /greater put dup 63 /question put dup 64 /at put dup 65 /A put dup 66 /B put dup 67 /C put dup 68 /D put dup 69 /E put dup 70 /F put dup 71 /G put dup 72 /H put dup 73 /I put dup 74 /J put dup 75 /K put dup 76 /L put dup 77 /M put dup 78 /N put dup 79 /O put dup 80 /P put dup 81 /Q put dup 82 /R put dup 83 /S put dup 84 /T put dup 85 /U put dup 86 /V put dup 87 /W put dup 88 /X put dup 89 /Y put dup 90 /Z put dup 91 /bracketleft put dup 92 /backslash put dup 93 /bracketright put dup 94 /asciicircum put dup 95 /underscore put dup 96 /quoteleft put dup 97 /a put dup 98 /b put dup 99 /c put dup 100 /d put dup 101 /e put dup 102 /f put dup 103 /g put dup 104 /h put dup 105 /i put dup 106 /j put dup 107 /k put dup 108 /l put dup 109 /m put dup 110 /n put dup 111 /o put dup 112 /p put dup 113 /q put dup 114 /r put dup 115 /s put dup 116 /t put dup 117 /u put dup 118 /v put dup 119 /w put dup 120 /x put dup 121 /y put dup 122 /z put dup 123 /braceleft put dup 124 /bar put dup 125 /braceright put dup 126 /asciitilde put dup 161 /exclamdown put dup 162 /cent put dup 163 /sterling put dup 164 /fraction put dup 165 /yen put dup 166 /florin put dup 167 /section put dup 168 /currency put dup 169 /quotesingle put dup 170 /quotedblleft put dup 171 /guillemotleft put dup 172 /guilsinglleft put dup 173 /guilsinglright put dup 174 /fi put dup 175 /fl put dup 177 /endash put dup 178 /dagger put dup 179 /daggerdbl put dup 180 /periodcentered put dup 182 /paragraph put dup 183 /bullet put dup 184 /quotesinglbase put dup 185 /quotedblbase put dup 186 /quotedblright put dup 187 /guillemotright put dup 188 /ellipsis put dup 189 /perthousand put dup 191 /questiondown put dup 193 /grave put dup 194 /acute put dup 195 /circumflex put dup 196 /tilde put dup 197 /macron put dup 198 /breve put dup 199 /dotaccent put dup 200 /dieresis put dup 202 /ring put dup 203 /cedilla put dup 205 /hungarumlaut put dup 206 /ogonek put dup 207 /caron put dup 208 /emdash put dup 225 /AE put dup 227 /ordfeminine put dup 232 /Lslash put dup 233 /Oslash put dup 234 /OE put dup 235 /ordmasculine put dup 241 /ae put dup 245 /dotlessi put dup 248 /lslash put dup 249 /oslash put dup 250 /oe put dup 251 /germandbls put readonly def currentdict end currentfile eexec M#1H5 J6o \&rtS(#v\0\޹V7Fe༙OYx5-cY9^%Y6 (efIOldN"wȰ;)UƽoFg/rvV$JS8_oc@  o9-eGJp}[Do]mN=4*{ܯq=eU^t6¤)w Rfxpc @X$UČc@:p:20eַl&^ ZXs/ 1# PGh&ɹ!R0gAZ "2 w^DVMܽ/x}KA©rhE=V~xYaI샌0 DNP)/LxN> kvc߹vutSs G'wId.t!B^nL:]u隣 \F"8\xS@v'*bt a̓;yº9;i[ֈt(Oqn`MHwT I *faQa2۳77"1d PxwT<a~f-~%r\簂ܔ?$v" PO~zD52H^!ݒ/ ʮ/t]n+?o\;VUQf3)"5/fOh-ܥ sdqG$h6Ԍę'ˏi>- zu?(wRh+8 l11 U\ Rtq ^T=.&?( !3-GԂ_K>%0O8 ~-A ІB;cyt^Bd/P55\ʽ$j8)v2 CbT!1<I gq^%öR]"vŐ@Ngc~= E)= ZgyGVG!kefkV><28d;VeZˇI:6 jC9}VYc\ؖ%$APvvv~-],y 5}(-Ś#ũ5gNg~_xY4cz=fg@'QI(~ݗ8Vj)@hEPs~p l!^po+(p(}m)B̘Wtu 'BX5;rC-%m?̫eb~{NSC"7Z#yՋ ?[`r+p#8)b~c۬67g\(g4Ek{T;Ҁ*Xی"9dZ72uygGzz1̳ݗUʼ3z4PڱT<Vc|i2午};yDj|p ֊t^|4E!~JƾbI ̮!&GRE>YMvԸűG J?|5Za߃8p6#hF?qVs4!}Б ǯ4{D`ψa"C $^kWf Fȧ!ΰ;V. mo.'bDˠU'z3M\gDgFZ[9z$>We+gEt:;᭿ /m× לDzeX+OAfIYϕ(+PlOECV}d ?nXV32qñ$1Ѧ' cLW{ӫk_d꧇,\I>1_!F Hj'p6%a4])u~2)NbnLoaE2[R=^:  MŘVx(]h7(ϊh龝KI:t4{[ծ1꟥isA^ʊFe|@pCu:K ]ixy% C3+yI28hvf=eYE|]$VYeS:xjx\FDMn5k:KjX؁hׯ>հL!/|;*)y}@Ɣ'%;o> =zhX)!+a|)Hdg6'* j{Zxl5#AaB~1Yܨl NhFRXPq""#whN v`%郼VzG/øӓ3! #땜D, 8U ЇƏlZ_i4AtQj887nKjlJ꾍U03НSo^|sD'S7D}\`BQnLcJ׭"0kW5T"G.EHBqm3!ZBrrKћq* nT!DA0 GnAk)eXi \Mt5rp1|cIC ArqrHFI";gw,d_TS),tdܨt.bv_@7Es|{/;Yjm]VQf" _tEyy)x/Qe*sx,'qPH2"*!>w+J!LOƨ1M5v6t$LE[S_@P=; DLд|@3JǫA4?~սmD[NS劈+CFbؗƻ1p{{c#F+ sw^>L?D+!J޳bSoLeY?XW=I $CE`'  ɟ':uZf.(y^gCx ^mXj]nxhR:EW;̭ ^/}Ir.R/z?*WsiÙGsHxݚmIc9[~@9/wRG}j:J '`>B7nc 1@*fy75ݾbism/xZBl||QHJSe, 3ȗB Qy>N$>K~vJ&%R!}rR(+v.$?'%OP[-2H X~ugu^q.j g.58JR8E;MYCݕKm4*WlM´njt6Yf ]fI#-m;V."$CȪ&?s#&yBf%_M[,[9VE8tAafV88V/UI9Q$t\S&AS}˗}{ 6tǠw0HB%skLiQk$-Rj"yt4^ sb[ ɒSVC fY庄ፗJ8.#=m"hA:Pt?u ;K2/Ŷka] 9VXS2vj{B7v7Eݢ!@g=RZ8k?3O`Pxew"S5cOG;A؈ïB9W v1bvp<"+Im:lk1Vұf`6/lD3Q5նa?,;=L5KEtɮž7`d-T-_9MP-0**y^a^4c1)IY>Y +I}#aI2Įd^b% ;{H#@zSeSB=fŏdt{C9| *u%J@vW yjh+VnitZxH Z>")D%$k#$g:8Z,ubt:݃hx%BH_-#:F+jj#T{3J4h2ϘG6w荼]X/hjt":/??@UyE@7ԄLbѕkPttPy~x7ߊjנ.زwn8e+VdCQ2GSAi g\Dm^!8y;ej^Ƶq{cjj͊oCm,ĒpۧzNH!a=[RոH[>~O+Ku!-N:?^ 0) zX6. _n016{Do+ fߌ$UMΪ},8_TN .[*29B5 r&-_*Hʤ=7NV9Nm>5+{}tw hD1S 6ttb:P6䛦m EgN|p^><Ӷo^(37=:z+ ^>dhPb 9{(d=6]}L ==c )Ac+6SH,mBUO]%\֋֖ć-ؚk5ēHhUd ZawgPHՒj+CbfR)=}[s:̸kz{| P? euC0VZmZuVȨ-R:y=k@}^~CW+l :abLM.c!d*HO  =lxc wEi_!&0ʳ Se݆X|ߚ&T&'Ye,Π?'K.N z&p+Q]^NL x))ʚq2 3#w=ysstڛp ,0V0/-?Vg/q㿠: {|xVh((+XM|SS-<^G`z@IF~5p.o61訕|Є^-Tf'ͳUEbf{ve,Rg-|~\ 6٭PAT2t&6l%'~xu{1V&qE ֪ E4<C~y3B_:L]IĕE,8oN]`(i%|? SDr/]tp}T78B^Po"C~px:GGKmGonp-.RÜyKӐ0` ofsc;^xC ⸞hӷ?<À(F3Qw7f90WmhDfi\Gj&7&գS(We}BuHvf 7&Y%ewDBDO`r}۩0UTݔc~yћ#~J_Īk1]$`~4*ӻ^!Wˉbf|ԱCxE\mXlc<ͧHk!:^yC1vpQ^TT G3`ZɕEdJ> H.3 +Hrm^RnKѪ}N1ں9rW d Y:iwdpFG[Ld lCn` J&l ?oBOw٣E$.2y|T7 ۑa>X7(h|G dpoځ lXx:$Z8z[La76}~j8W ?s_}45 ḡ9]5CQ쯤IGp()wZ>|%{^B>z=rIVlQbWy8d Pv?pu(޽l3N=H-<RZ`^w1*0E i(c9>'-LR}ο.YF_[԰l3PJ9f/lϘjb*d?0g[s-Ee MsSk Y$>$1!#?P/"ɳ<_oU@ ].51KjR4#^h5]@2${0{PDm!06TP%rO݆?ar\*iHBq[FoRM XI42 k `0(^e]Sz >WywE1J?r{84^soڲ 7tQV "bEOxD& Z$KmA|mp)J9ocC9];nQ\:37 r[ѰhG)_/k]iJz` 0zj Xop08dߴʴ#=}؎j4=vOe#:ҫ`ߎ&jĥdiZRP\ׯ _{gM_J>&}i??7F@%Kwuk(sW4fm7F3hnR>d)#N|Nڸ͏7ԝ V.I|yvF#:1 4NuĐRy35^SQ}6XVt& Ul1ԏg)ZcJ<cB o](9%+"nSeԿ*F ru[jM p:]g;|M~R2\אQ41-i$.2*5y)9%z91Oޗ"Q7f/׍ޙ'ûs8EipK6sӌƴwZ\i,HI#OyB(yGAvYx  w[JyoE˅<*t"v[=Σ>'i\JnpzX*۽X\h5*?#Q˞U~^֊ǥ5s%A۔șƓh-ItfJO7~J%Dp:„*@ǟ}fҀx'9[PXݏvQjơtfpd{f|:C8F?(L5*B^[ZS _fÜ$Ϫ'Ao$ax&*=&Ci )KT^ j;LdJ(0-,:Fɱ͛ʴɕ  mdD#loddA7p}`^rދر|Ջ,:qS_<ׁ yo{>BP&U{o 9d:3<)E$È\FĖ(CO'{rhAf]Oz\-,yƵb57@:5@xt?;=Vsi̸z i +OFa-/-+!my/"1ʷ9=NK[!'y.ڬi֮m')9#g=# h>u;N滑؍{r􅐍EM 5=<2R̗ŝ<@]#K|emS!/8aBI/fr*-&˺U;U؍G"*/%ypޥ.E ^-E`)/*.no~ߞR&I}8E'7 Gnxit a1-N56z?XZZi7h4Ja74EFZ/髫{(gK6ezIfoiZX2BkxI0sbHlẕwxw_qU$7󜑛8b^ 3BI~Rݚ\L'Y&w&4c_- : ckoIl(9d :(ˀ7BoymS#>0Ɵ//ЕMRhA/Z&=Pn܌-1<(sTh!"c>]*v7[L޽5W操 I<{ T@+v3x.fl7=O;nʴeT@ƣ)gž}8tCY)C:}O,1UtG5e2Y!P(?ÌܛCK$@cCڠAHvN@l h0l6k妏HyRc+xbqۃ{;OãK=8yj?a f c#[i^Eg`;U{֤-}v mܤk;xqK-dp{1_(KJxMo˸&ʦD?i@ɛF\ySbB.NF6@,ꕻHhggO٣ % v4C*{'\cc,0Fk$p =Wtǧ/WyׂJ܆3`Dg;u~ee~eR`#{a;O?;kt-$fN֠O/MЊ(cjAnV}r M 2hW,IRWܾz=GkqY0'.Z(&ۧcY패Rg9& O+ VtÂdӒxyyEDevL HDyqSFu֥vDϨFJD`gaeԤH.ZFnn?eHkz#rvb$\c6Hr JW' .D&L<6CwOAOqãΌjVV\6f~=S5/3n\[9V 6sѴj?Iր_忍EXo[\1&q"@ii ?Hꜩ,M0?K 0R6 \w1S x%RQoW_Dۦ(E!ވJFsHpBT^52 o9DU+"dz5vs}#3&EeAy/?D/h#-C-Nѷ%t7y^07C1'T̀ʺN \#g8sz<7Z2}zrEOkLL)N Vݛw{{&ٙ㫎ڃSLEAO9wO2ewГR7벶K%I# 3#ma8rZRN+i<ʱD:"8zP$V#F9A Ġ{XnOd8UGwL}[=7!Yg7f} 'Lx[>q\~ÓMŗl{ {X)@Q:"H™9M$ć7սJ6̔/q4+Y`e '.cڂñ~pԤ-iFy=w%6g? ~i >a]r\T{F0U!IMGeT*N@^AB6j Ӥ]9n8 G\ N4u5ǮFCd~Τy ߤk9W̄- %^ > Bt%i~}46Σ}10o3tCk6?j.e|^lNK\10j`X|?m'\l{Eye.R n'YƾZR ޥ [-^d>d^(f};&_TXظk}% (" Y@yU ui4-' ltDE n'7#0,}'xF[p0|tlɝBPƝ*!B#[|Y 3J> ngw?j[9n8 6(Hm򳦌Q0000000000000000000000000000000000000000000000000000000000000000 0000000000000000000000000000000000000000000000000000000000000000 0000000000000000000000000000000000000000000000000000000000000000 0000000000000000000000000000000000000000000000000000000000000000 0000000000000000000000000000000000000000000000000000000000000000 0000000000000000000000000000000000000000000000000000000000000000 0000000000000000000000000000000000000000000000000000000000000000 cleartomark endstream endobj 770 0 obj <> endobj 786 0 obj <>stream /CIDInit/ProcSet findresource begin 12 dict begin begincmap /CMapName/Adobe-Identity-UCS def /CIDSystemInfo<>def /CMapType 2 def 1 begincodespacerange <0000> endcodespacerange 1 beginbfchar <000D><002A> endbfchar endcmap CMapName currentdict /CMap defineresource pop end end endstream endobj 787 0 obj <>/FontDescriptor 788 0 R/DW 499/W[13[629]]>> endobj 788 0 obj <> endobj 789 0 obj <>stream  cvt &=& .fpgmntglyfhPlheadh6hhea )$hmtx鯔4` locabFbzmaxp  prep{WP"U< _< :JA * *%4444444444444]Ncq(l oA S 1 KbQX!!YKbQX!YA2##########################,ITXITX?87YY-,I@TXITX?@87YY-,% )`&!-, KbSRX Y-,-,-, -,-L& -  wba ^   q A  }  _ vw&[. yrr9rULBz9|//d C221{5bAhc 4LVLgPLT<[zeLpy[{V|W-yr5Zr7r2[{))yxLVLVLVLVLVLVLgLULULULUNz[[[[[vvvv      FF#  Cs)o' BxBZyUZ&7 },rrx ))xqBm  }|r2{3r* gx=: 6))9^999xxLxo = 2 d M     ,  JL9 0bWb[%Y{3r2{g_r]9/bWyLgyLgWbL?A?30//0/13!!!LffO@ p    p   ,#<3LC       ?220//]0]/]]]]1'71%%1'74lj4̹jlw+a"a++b"b+ endstream endobj 771 0 obj <> endobj 790 0 obj <> endobj 793 0 obj <>stream Univers2= > endobj 792 0 obj <>stream /CIDInit/ProcSet findresource begin 12 dict begin begincmap /CMapName/Adobe-Identity-UCS def /CIDSystemInfo<>def /CMapType 2 def 1 begincodespacerange <00>endcodespacerange 1 beginbfchar <01><002A> endbfchar endcmap CMapName currentdict /CMap defineresource pop end end endstream endobj 80 0 obj <> endobj 794 0 obj <> endobj 795 0 obj <>stream %!PS-AdobeFont-1.0 %%This font is a conversion from Helvetica-Oblique with the following copyright notice: %Copyright (c) 1985, 1987, 1989, 1990, 1997, 1998, 1999 Adobe Systems Incorporated. All Rights Reserved.Helvetica is a trademark of Linotype-Hell AG and/or its subsidiaries. 11 dict begin /FontName /Helvetica-Oblique def /FontType 1 def /FontBBox {-166 -218 1114 770} readonly def /FontMatrix [0.001 0 0 0.001 0 0] readonly def /PaintType 0 def /FontInfo 8 dict dup begin /FullName (Helvetica-Oblique) readonly def /BaseFontName (Helvetica-Oblique) def /Notice (Copyright \(c\) 1985, 1987, 1989, 1990, 1997, 1998, 1999 Adobe Systems Incorporated. All Rights Reserved.Helvetica is a trademark of Linotype-Hell AG and/or its subsidiaries.) readonly def end def /Encoding 256 array 0 1 255 {1 index exch /.notdef put} for dup 32 /space put dup 33 /exclam put dup 34 /quotedbl put dup 35 /numbersign put dup 36 /dollar put dup 37 /percent put dup 38 /ampersand put dup 39 /quoteright put dup 40 /parenleft put dup 41 /parenright put dup 42 /asterisk put dup 43 /plus put dup 44 /comma put dup 45 /hyphen put dup 46 /period put dup 47 /slash put dup 48 /zero put dup 49 /one put dup 50 /two put dup 51 /three put dup 52 /four put dup 53 /five put dup 54 /six put dup 55 /seven put dup 56 /eight put dup 57 /nine put dup 58 /colon put dup 59 /semicolon put dup 60 /less put dup 61 /equal put dup 62 /greater put dup 63 /question put dup 64 /at put dup 65 /A put dup 66 /B put dup 67 /C put dup 68 /D put dup 69 /E put dup 70 /F put dup 71 /G put dup 72 /H put dup 73 /I put dup 74 /J put dup 75 /K put dup 76 /L put dup 77 /M put dup 78 /N put dup 79 /O put dup 80 /P put dup 81 /Q put dup 82 /R put dup 83 /S put dup 84 /T put dup 85 /U put dup 86 /V put dup 87 /W put dup 88 /X put dup 89 /Y put dup 90 /Z put dup 91 /bracketleft put dup 92 /backslash put dup 93 /bracketright put dup 94 /asciicircum put dup 95 /underscore put dup 96 /quoteleft put dup 97 /a put dup 98 /b put dup 99 /c put dup 100 /d put dup 101 /e put dup 102 /f put dup 103 /g put dup 104 /h put dup 105 /i put dup 106 /j put dup 107 /k put dup 108 /l put dup 109 /m put dup 110 /n put dup 111 /o put dup 112 /p put dup 113 /q put dup 114 /r put dup 115 /s put dup 116 /t put dup 117 /u put dup 118 /v put dup 119 /w put dup 120 /x put dup 121 /y put dup 122 /z put dup 123 /braceleft put dup 124 /bar put dup 125 /braceright put dup 126 /asciitilde put dup 161 /exclamdown put dup 162 /cent put dup 163 /sterling put dup 164 /fraction put dup 165 /yen put dup 166 /florin put dup 167 /section put dup 168 /currency put dup 169 /quotesingle put dup 170 /quotedblleft put dup 171 /guillemotleft put dup 172 /guilsinglleft put dup 173 /guilsinglright put dup 174 /fi put dup 175 /fl put dup 177 /endash put dup 178 /dagger put dup 179 /daggerdbl put dup 180 /periodcentered put dup 182 /paragraph put dup 183 /bullet put dup 184 /quotesinglbase put dup 185 /quotedblbase put dup 186 /quotedblright put dup 187 /guillemotright put dup 188 /ellipsis put dup 189 /perthousand put dup 191 /questiondown put dup 193 /grave put dup 194 /acute put dup 195 /circumflex put dup 196 /tilde put dup 197 /macron put dup 198 /breve put dup 199 /dotaccent put dup 200 /dieresis put dup 202 /ring put dup 203 /cedilla put dup 205 /hungarumlaut put dup 206 /ogonek put dup 207 /caron put dup 208 /emdash put dup 225 /AE put dup 227 /ordfeminine put dup 232 /Lslash put dup 233 /Oslash put dup 234 /OE put dup 235 /ordmasculine put dup 241 /ae put dup 245 /dotlessi put dup 248 /lslash put dup 249 /oslash put dup 250 /oe put dup 251 /germandbls put readonly def currentdict end currentfile eexec M#1H5 J6o \&rtS(#v\0\޹V7Fe༙OYx5-cY9^%Y6 (efIOldN"wȰ;)UƽoFg/rvV$JS8_oc@  o9-eGJp}[Do]mN=4*{ܯq=eU^t6¤)w Rfxpc @X$UČc@:p:20eַl&^ ZXs/ 1# PGhjtUDA@tZ.nr[ , "LvJ˜LVguˏrF.Cv \Fջo. ϛo9aѯxyNh <Іi@qlZz}g2tMag"j e,Ѥ5,[LPE5>ޤfȿB҆}_f☷?QrQYr$#h)[ Y׏#)793imTV9b#j2-<\(IlUWwm5q \ѳewY j.Q5ˈZ]7{dEq"•2T@cQ)Dso;_H6[l]Y6*'ɾ_I3ajJle>/:˲{х40lD/](09ܜ[5YJ` *"6:EmUS^KԮXu*ObZ mj߈5F,çWHX?풸#Pu P^.DCszꏺ}%VX'8xPyZOVef"\7wËj@C"FW_КйxG:tT/}I5nͥ03hţ'"վT-tCSvC>e8$L+ֆ68Y)'Rr<3, ΄Ds)\fy0s [ZX)Ebr-%AY렎 ]e `t?^Q=Ta0B'嗏(XQJ'Ec- Hr 9C5Ǭ1<&ļ txPaUmd:|Hhf58?ȥwO'j3ho;{&_f4d籘?8B_ ͉[bBaؖMl9sim|oYA˒nQQ2Tȅ5MgZZ{{Eb̶^NiǨ_tRyRAV;̧G%52ޖ2eܡ=ܮ!~G' 3o2àWHlHmCG]CK͏s 6̌t9Hϔa^8@fϋƩKM*$@kd&jd%\: Iu ~8WfA?7ztfn4ލ-[܍>{=κ櫴ʰ!}f<(W\)J#K!.*Pt+aEڔ΋$a⡞4Aֿ sb6d)2x{.* *Fe0X"ؿnPmp:&ՙG kjbMҌMߙqYa*\TN],xg:-aq#H~s/ veUEQH2;Ya@l5ac(gwz ޜ2VRqv?-pN8-]C$n@ H'VqQƋd;< ݾkǫ0<)Z{UDڃu[\e8?ͱfT|azsfثGLBy{ϱ4W<7shpWn<`l(A6,H!EY83N%-%N8LQ*N(md lNq,@v}5,0`Uc9`I#ӄh0 g#z+]tX5 ZB\H?.k83ψ@Y/%ov6Gпi%,>/:5䝐 & }qnnoP^^&ZO->g}bK(P.e`+b-κ@8 sV;x m׎A)y֗6/J/ܦNPx(y;$ؗ~`bu $OY5k^)nƑA1aOG^dvd{5}l%tZ&)f#2>j<&‥ADҏf#5/iĚR&-%yKW?TDQE[ 5: h5 +Nބ߂B;%{"A*vJt&N%&۩V-VU4M7070,$A^Y1%ÿ~he 1U`mN &'Xk^YUKE'Ը>yvX F<)#q @3@6 klv5xN !!`D^T67 yWŮRu[}œ[&u}bG[Z:jԭZ@68V㛫fy>x9k]Uq)}aajE7`K[W. Z{TٴU(%2.w+ngEϗ {:蒁IH$q2 zI{ȠCEtF!֍͟kD!kC(:w5LH}iVǪoB<1~;0U@O(dڞ©y} 6Sg[⩴Ng\ m-"tS1 C=gFHK,YUHIpW n" FVQ(CCE1ݿA gHbs,߄~5!Mlb.wyi3$>ANz3:1"P,+ ԓ8GE ֽrio0d<1LWIGo¡rd]L5;1-)p.Zηr# k7x6-O3xY\^Hxl<gY}čƺ7dj7̅]ԑJ,mA];Yϖ uKP|BNbVO@!,}ɘ@YobHan='hbS/ғ3ҺzHtZ*̫HGD\έx\vMAx,f`,SLΈqjVcyĿ޻HdMdA :Ǿd9gy` ~.h}}=q0TO6&rA;|Ô"$p%>a?voD\e-$gĀ^ν|ii/;V=(@sFKVm̉cObxrwZ%p 0CSc&l:W0ٗ_xAC8hzzO Ob4R#7nj}ORߙ-9R{0 ,2]Յ|Pi#i|CK"3vLhwGj̈́>Bʳ1۵;DN %E3UP8BHI| sųot9<~" jή[2*z[LlO&?cRBVG"Iy$bt!Ӝ&.a4X' ۴QXc)I2K&wܻ[HVRpBH^eM"I b8yK̎܄4' R!R*9_-c``[b1vIaIfK0Q>{Nbe@  ժhB,TB"[WrKUPuF-~ "! y=L}S|ot *E$Hntڨzz=H8y#[z ?؞υb# b+Eyr+ƒkTŝw4u=>ZNfy`f^)X ;rx/gp$jgC.LnP b\⿇{&cn^rdZ[ GوM,H@k2lģ *~[lZk bN 5h #+l\o1UPÈ;4Y۱2ei.g9ݕݺ!C灞ëN]{'hT3,pp8MWIU*EQZ:EaKQA zdt6#YCM_Ƨ%}Su&Xw$MkW(ATezN`,Zfe `_Jc@'Q =!.~ Y~de?$:KMZ@r]Ľ)g xO&{D34J+\N'E:lG8W7ݐn8jX)s_hv!-T& M. 1 o&_&ayxdAfUK\{$|J4X.ֻ|[Xw^ i7*ZOR&kq1s`S11,)?W i]#.ƒXk3f6ZZԑ7O#q{,[]2 |7#mGw ΨŦYa6B$q;R ܚ8G;R22.V#}KQf0EEg٫O5a2Ȗ +#˜7/=Bȁ%DL#w7˧+eQuַhB[y5l!mZHZربa)E Yd}'7 9>͕t}a2vuL ے^5 W/@ ȞRILZ[Đ7v@i6]t,q1<9` 1?4D\?8l9g8HD_eA-B,ožmM[\J\10*+V@tg ܹA\JYEu{]"?جj7 ﮭk9" ewcmPZf#H.X 0ЩдPhwD@vJlU,HkGj vƛ>C B]olAI`g/HŖVoZdrU"'::ʵ2te\%v?}"-)b!d^D^V-s q 2B;c=3ᦤ hohui̘$ 7y-b3z◇smBՈNyHV{S>aF^p܂uv=ڕFlW]~M$jQMq2JDP1B6@UfiI 3wR`dO7֔p/ ,d K&\ 7մNԵMF0>}U2n/} H^dRlOE䡢/8lٷXwp) BG&Ƌ̹L*ˮ]jjNǜ3寅3]rv~:"hK m4+nY(?g-*DocCߢgyZ3I(~j.G~^CMA]Yy{u79c'cTVuΈ8̔15hUwQ-7{ ߧmZ_1 AݰG2.d ƭ_U$ )~㸭6ޔ{`F}&g;쟝-)*NIa!0rlނ @DKG&z/)s˄ͰJ_tÂd.G~̈iτeTʆ   ε|Y39fB'T5ef:.Ys6#;iH>H(z]ᯑ?>gC*ttI7uZ x͑ՐF/VmseRŝE5]9Kɸ`)%GUEwc&GN4@^30@ o6Q?(L+K,q&`yҖt-);7q9R+ͨQZѠZ8=;Mt3+ed/e vj~5kSĽe:Cf2V؂/Wog>Ke=P0Ⱦw>ɓ}њ*\cjk}cmŇrbL GwUX4I'{PLAdrD$CST@.?J%37@5ͯ]7ZQ k&ϧںk2m*t$kF"3򼞄j"6hef&^p(uRdtgT͒KR6;݆ gˬq SbY~:4Y%lWQ_{m۸XճL]C3X`n߼@(VF) r_XoF%s'VDwR:!;<3G$M0d""}řPNedw$X4JŇrO;}+a 1:YsWۄO>jkҌD6ĢI@&@x@`)MEF9, /!O.o8,;]TrBBm# ^ m ZFp/U<𶢁mX`akžu^6wЪ[}*D{VeSc9aU^€g& 5_7-)ą&K#ihjK*f~cpViW,Ƭm##}OAf)ZjV6ymG ‘=7])Ɋ^Lkg.wgE;;{G8djZB9[k6,}tG,^'&σ~Aex\ہ: rӊ6?CkvgP%Hl'll$>:T:5COŝȆZMjpG㫳=P3QxMV^҃2-TQϭ$ v"W0 ~V SMyb*qOw?L\Y+&o9O|`/Uf ?<k'}tn5yLyCجҔ0>֠z-Ӑf>?岹3:$4H#S屷qᴟɱ7-ٱ>*ƲaٽʁLK%k߾ϭ_?컞Ǻ̡<̟fQ:` a'r Fo6-Ψ9W n Ow}<{2HK0O,gE&P1$ґa\`nFi)rPN,whhzڠZ%dzC^M_&Y1QHާGP5lDev<\ں솵[oz(+cQXC*LLzOݽ0& 9OЩ3\ j39cm8+S+F)׉h[ P [mzɖIF0RQu0 N?"c2]OmXHe0Ba={jq>MV3YT^{^_ CDOlȴNBB1C5W;B'jBQxN3s aD \t4r=J#6{{z B3WE>œx]^r` ЌugimTJG[F,A\fȷaK@83c sd"dY a5Q]7 semU:Mt;E2~ԓԳ{Y1sUj"Xm=ɢ'=_.h`^_jAÀVǟLzCuRH20i!.,T*ዟB%B)_ueX#E[5-σD -M @%N2 a̹Ф#Wɞ=$1]_oma[(xag Ųn3#s'pqK}¬3A pS@aUط6CJW3~LvMz=;^|G:0${<'PO rE:W%`GKD$TTF\z+ޔ9B$8V};ϞgxF-d=7`}+mڲBzfв]iCtCLb  h5J,T)Gܻ:D%%ɪlȹZME֖;h-"`A\A$fOɍkn%RFy$cXzSJEKH]$ϓl;Z75q0F|EoԌJsE2P݋<)EV{G>hAP'[ aY| v:DoާCp7g7zcp=j|ٿg50`yP}T8lYYܟb[)8K9_5t;0\mtGhmZ0000000000000000000000000000000000000000000000000000000000000000 0000000000000000000000000000000000000000000000000000000000000000 0000000000000000000000000000000000000000000000000000000000000000 0000000000000000000000000000000000000000000000000000000000000000 0000000000000000000000000000000000000000000000000000000000000000 0000000000000000000000000000000000000000000000000000000000000000 0000000000000000000000000000000000000000000000000000000000000000 cleartomark endstream endobj 7 0 obj <> endobj 796 0 obj <> endobj 797 0 obj <>stream %!PS-AdobeFont-1.0 %%This font is a conversion from MinionPro-Regular with the following copyright notice: %\050c\051 2000, 2002 Adobe Systems Incorporated. All Rights Reserved. U.S. Patent Des. 337,604. Other patents pending. 11 dict begin /FontName /MinionPro-Regular def /FontType 1 def /FontBBox {-135 -250 1010 750} readonly def /FontMatrix [0.001 0 0 0.001 0 0] readonly def /PaintType 0 def /FontInfo 8 dict dup begin /FullName (MinionPro-Regular) readonly def /BaseFontName (MinionPro-Regular) def /Notice (\\050c\\051 2000, 2002 Adobe Systems Incorporated. All Rights Reserved. U.S. Patent Des. 337,604. Other patents pending.) readonly def end def /Encoding 256 array 0 1 255 {1 index exch /.notdef put} for dup 32 /space put dup 33 /exclam put dup 34 /quotedbl put dup 35 /numbersign put dup 36 /dollar put dup 37 /percent put dup 38 /ampersand put dup 39 /quoteright put dup 40 /parenleft put dup 41 /parenright put dup 42 /asterisk put dup 43 /plus put dup 44 /comma put dup 45 /hyphen put dup 46 /period put dup 47 /slash put dup 48 /zero put dup 49 /one put dup 50 /two put dup 51 /three put dup 52 /four put dup 53 /five put dup 54 /six put dup 55 /seven put dup 56 /eight put dup 57 /nine put dup 58 /colon put dup 59 /semicolon put dup 60 /less put dup 61 /equal put dup 62 /greater put dup 63 /question put dup 64 /at put dup 65 /A put dup 66 /B put dup 67 /C put dup 68 /D put dup 69 /E put dup 70 /F put dup 71 /G put dup 72 /H put dup 73 /I put dup 74 /J put dup 75 /K put dup 76 /L put dup 77 /M put dup 78 /N put dup 79 /O put dup 80 /P put dup 81 /Q put dup 82 /R put dup 83 /S put dup 84 /T put dup 85 /U put dup 86 /V put dup 87 /W put dup 88 /X put dup 89 /Y put dup 90 /Z put dup 91 /bracketleft put dup 92 /backslash put dup 93 /bracketright put dup 94 /asciicircum put dup 95 /underscore put dup 96 /quoteleft put dup 97 /a put dup 98 /b put dup 99 /c put dup 100 /d put dup 101 /e put dup 102 /f put dup 103 /g put dup 104 /h put dup 105 /i put dup 106 /j put dup 107 /k put dup 108 /l put dup 109 /m put dup 110 /n put dup 111 /o put dup 112 /p put dup 113 /q put dup 114 /r put dup 115 /s put dup 116 /t put dup 117 /u put dup 118 /v put dup 119 /w put dup 120 /x put dup 121 /y put dup 122 /z put dup 123 /braceleft put dup 124 /bar put dup 125 /braceright put dup 126 /asciitilde put dup 127 /Euro put dup 132 /Eth put dup 133 /eth put dup 134 /Thorn put dup 135 /thorn put dup 136 /onequarter put dup 137 /onehalf put dup 139 /plusminus put dup 161 /exclamdown put dup 162 /cent put dup 163 /sterling put dup 164 /fraction put dup 165 /yen put dup 166 /florin put dup 167 /section put dup 168 /currency put dup 169 /quotesingle put dup 170 /quotedblleft put dup 171 /guillemotleft put dup 172 /guilsinglleft put dup 173 /guilsinglright put dup 177 /endash put dup 178 /dagger put dup 179 /daggerdbl put dup 180 /periodcentered put dup 182 /paragraph put dup 183 /bullet put dup 184 /quotesinglbase put dup 185 /quotedblbase put dup 186 /quotedblright put dup 187 /guillemotright put dup 188 /ellipsis put dup 189 /perthousand put dup 191 /questiondown put dup 193 /grave put dup 194 /acute put dup 195 /circumflex put dup 196 /tilde put dup 197 /macron put dup 198 /breve put dup 199 /dotaccent put dup 200 /dieresis put dup 202 /ring put dup 203 /cedilla put dup 205 /hungarumlaut put dup 206 /ogonek put dup 207 /caron put dup 208 /emdash put dup 225 /AE put dup 227 /ordfeminine put dup 232 /Lslash put dup 233 /Oslash put dup 234 /OE put dup 235 /ordmasculine put dup 241 /ae put dup 245 /dotlessi put dup 248 /lslash put dup 249 /oslash put dup 250 /oe put dup 251 /germandbls put readonly def currentdict end currentfile eexec M#1H5 J6o \&rtS(#v\0\޹V7Fe༙OYx5-cY9^%Y6 (efIOldN"wȰ;)UƽoFg/rvV$JS8_oc@  o9-eGJp}[Do]mN=4*{ܯq=eU^t6¤)quu ͟:LW=1UB̵X> Dɮ"\ :띥W "V IllLvşe=u.n,+kC "'C>84ۊ4$e&U! 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All Rights Reserved.Helvetica is a trademark of Linotype-Hell AG and/or its subsidiaries. 11 dict begin /FontName /Helvetica-Condensed-Bold def /FontType 1 def /FontBBox {-166 -239 1083 843} readonly def /FontMatrix [0.001 0 0 0.001 0 0] readonly def /PaintType 0 def /FontInfo 8 dict dup begin /FullName (Helvetica-Condensed-Bold) readonly def /BaseFontName (Helvetica-Condensed-Bold) def /Notice (Copyright \(c\) 1985, 1987, 1991, 1993 Adobe Systems Incorporated. All Rights Reserved.Helvetica is a trademark of Linotype-Hell AG and/or its subsidiaries.) readonly def end def /Encoding 256 array 0 1 255 {1 index exch /.notdef put} for dup 32 /space put dup 33 /exclam put dup 34 /quotedbl put dup 35 /numbersign put dup 36 /dollar put dup 37 /percent put dup 38 /ampersand put dup 39 /quoteright put dup 40 /parenleft put dup 41 /parenright put dup 42 /asterisk put dup 43 /plus put dup 44 /comma put dup 45 /hyphen put dup 46 /period put dup 47 /slash put dup 48 /zero put dup 49 /one put dup 50 /two put dup 51 /three put dup 52 /four put dup 53 /five put dup 54 /six put dup 55 /seven put dup 56 /eight put dup 57 /nine put dup 58 /colon put dup 59 /semicolon put dup 60 /less put dup 61 /equal put dup 62 /greater put dup 63 /question put dup 64 /at put dup 65 /A put dup 66 /B put dup 67 /C put dup 68 /D put dup 69 /E put dup 70 /F put dup 71 /G put dup 72 /H put dup 73 /I put dup 74 /J put dup 75 /K put dup 76 /L put dup 77 /M put dup 78 /N put dup 79 /O put dup 80 /P put dup 81 /Q put dup 82 /R put dup 83 /S put dup 84 /T put dup 85 /U put dup 86 /V put dup 87 /W put dup 88 /X put dup 89 /Y put dup 90 /Z put dup 91 /bracketleft put dup 92 /backslash put dup 93 /bracketright put dup 94 /asciicircum put dup 95 /underscore put dup 96 /quoteleft put dup 97 /a put dup 98 /b put dup 99 /c put dup 100 /d put dup 101 /e put dup 102 /f put dup 103 /g put dup 104 /h put dup 105 /i put dup 106 /j put dup 107 /k put dup 108 /l put dup 109 /m put dup 110 /n put dup 111 /o put dup 112 /p put dup 113 /q put dup 114 /r put dup 115 /s put dup 116 /t put dup 117 /u put dup 118 /v put dup 119 /w put dup 120 /x put dup 121 /y put dup 122 /z put dup 123 /braceleft put dup 124 /bar put dup 125 /braceright put dup 126 /asciitilde put dup 161 /exclamdown put dup 162 /cent put dup 163 /sterling put dup 164 /fraction put dup 165 /yen put dup 166 /florin put dup 167 /section put dup 168 /currency put dup 169 /quotesingle put dup 170 /quotedblleft put dup 171 /guillemotleft put dup 172 /guilsinglleft put dup 173 /guilsinglright put dup 174 /fi put dup 175 /fl put dup 177 /endash put dup 178 /dagger put dup 179 /daggerdbl put dup 180 /periodcentered put dup 182 /paragraph put dup 183 /bullet put dup 184 /quotesinglbase put dup 185 /quotedblbase put dup 186 /quotedblright put dup 187 /guillemotright put dup 188 /ellipsis put dup 189 /perthousand put dup 191 /questiondown put dup 193 /grave put dup 194 /acute put dup 195 /circumflex put dup 196 /tilde put dup 197 /macron put dup 198 /breve put dup 199 /dotaccent put dup 200 /dieresis put dup 202 /ring put dup 203 /cedilla put dup 205 /hungarumlaut put dup 206 /ogonek put dup 207 /caron put dup 208 /emdash put dup 225 /AE put dup 227 /ordfeminine put dup 232 /Lslash put dup 233 /Oslash put dup 234 /OE put dup 235 /ordmasculine put dup 241 /ae put dup 245 /dotlessi put dup 248 /lslash put dup 249 /oslash put dup 250 /oe put dup 251 /germandbls put readonly def currentdict end currentfile eexec M#1H5 J6o \&rtS(#v\0\޹V7Fe༙OYx5-cY9^%Y6 (efIOldN"wȰ;)UƽoFg/rvV$JS8_oc@  o9-eGJp}[Do]mN=4*{ܯq=eU^t6¤)w Rfxpc @X$UČc@:p:20eַl&^ Zњ s `?OVzJ 0qTG̝[Юya'ݑp&6C2lOqTqt""%vz6H֏y}ķP}Rկ]76TAR4-އI Y+I8UG|=|VB3m{RHǔU:VYЕ1j=1+lOvU"#w$…48P]FI/yTX$M(ՀM =G(g8O[H0QWr'/RH Bv878vhs%?R ѻ: *((Cyf2QeF0hSn\2-IthA`Ͽwgՠ)>w8ȍ[2k~ON\dkxd! ®esU JZZV @x5M kq@:/֒C`,wAoބNH@,Эs\]k[vFRLJLT@[&%;9hNz;y@7ʓs=>(֏'^1R%蒸j=YK`֚iOa7-_ډ E7`y\:K+4!6I qQI^L#V.J.Gg}4>mK?HF&su;SOfUA+uap48[}`d _\#4GV[[Wo\`rJ~;N(gHg|c;$5*_vFdM9u[JIH^`ړE+ oDf$ܨ2B!"V~@Rh_W&CѬPsX'1#dg4iH@l߱琍#z4g?̾HƇN̫zg/ IiA{+B/ŊKHOK"J ~鿠G5J _ /f􄓔du>YJ&0shk?nH.eFØOwd/0>ߖ['L9o$x&hk`w9'HЃ`~JTV5xL;ǻ͹ EҜ, &ѤS9t|=;YU#߰baM%Lh2k @ s29su44i{ENXԏqyB28)^u?łFuoL!D"Ĝp͹S 1:ջD'E~ŐRsΰk|mo!RTzggba~Rqۭzd%p>#+.;4ҭ՚h .XO43I JѶMV.j7M)J'躧lǀ&uf`2sZ(=YJ'Z1*c,:O AѕMH&qGE4BX#\>I$>"./܂ÁD,[Q_nMT(-f4" X(=rUjd)oL5֌B Fuw: yccc Ǽ:֡TZKdu!tKA}g \:Gy{nmlwBؠsk3]j <$FWrHdo*>Xl2C%T{;T@$(oVrC3(DiK#ҿ?@p&{sۘlR>Z0exJkhL d?K{^I0K@J@fW; \`ӤO5,,ɼ]_;NLz24˴u?MN:m=4qM҉*aR\px~5A! )dFp<Di1 MTɭ}12!ޘw¡_P2`Q>X7+\c/} ])+Q  ZOd6' mZAŹ{B'i fp} |"a +H`kC>h=f[$!C[`%ɮi{,[).|74͡^Ǒ6G&2+B8?[q|2ˁ- SgZ|`Ù1X\a\1Dk3+i h,Qk!*v`gݭi*Pc4౷oіɈrZQۃ큏m1cJh sgn3 L_EO1i2iRgb[ϊbnm/lѺp>ƪnBK$Z)10 xpTm6p%'P-$wb տٍa>Đ*%0¶1ղύd"̗ϰ>5ȳZ9G_o@~Okf#$ԳaԟD7Y_SsO!bf4|-])O^B:ND\ tD%]tLpPB+Z1{! ţ-ߣN  aZc2T0"~OAS^[R;+jד}0m[WQC^SA&sʵ/QA){>ɮzf[ hk0 F;Oc>.>PC-/ @3dե`@jC.L@)^Ӄvns%Nt?BzXi/6\UL4Iwe͛@-f7.г2Deq$Cy*t_p}z+pj_OG/%N/ hTF$'UuC -}!1c"]50X El6$ozg5p M&eė(Kh={Q|pNI%^pfO8)(h6Vh}܁G Fƨ늡>` W^&Cv{S 0͆Y62!࿥xMmτ}Y"a@S{&,&x-ȚBfI:p'6w6jE3?o'Hڊ᭺r"Vs0( /".]!NDm!Zdp>@&yk~c-{aVcoZUF"+p;d{5&DF;V3Fx!I5 %5]W2p  @dl,V/ d:%% h5FðTīfrotL0z]B>>ZE>NP r9|Ѫ2hMc[@zf;rhެRgyk.ayI]plQz3]B׺'M2) ]޶LV%,Qc:PCyFcyRm6K}ZJ3#BNU.qhFX> blmz4u>m t R6&@SQs+h!Г-@lz8n$" 3YR]da`f$}JGSRWwLi S\VS*^~H#[ UTZR ugn ;=V2 C9E0U|'0$WLg`wnIG L D|s?Ӿ 煐*:?;ww+~)NXP41`7ctqE3 X+>fbp-ђ-JwlGg&0S)~%K!ÃEd߷x:uX`/ьHW21['P&F/э]Ё .EҙKeȯxr2GwQ(G%-+_?p܀Td" ..+ lsn#)d%0(~&xGYhtMT(\O^/p_X z!ZDN1 Bx%m!y-^{@!+:#\>Z5s,z"B9ra]Y@mk3L,ƭi D_@dPj|Tz URs>O0d3):a%gN0.jmVrg(hb32TcMƝ0Q0 "d"5,8ȅF+0) m3l6* ZK`+)ƕ., \> Ƈ#ڱܳ[ڎ:-E5/>KFƕ6\&(g 䙣{_As@[`U㱛T~*i]SXn_V [$MWY6m4('yz@5[Q$8Q; Rs/#yn4wIngzqner{G_:lG Cݠm4.UҪ}%'8UV&2Ƶ3P/mςXYiI;ցfpO>/ٻVS!n⩌<(jCdEKVSwܿa'$L4}Sz} \,w=W٢gq`ՙV>fb`iX芩d{Gcɯٙ\HrJY]+#c{PUgz9:V`v{~j1QV*KKdK}[ks+C Vz*CʶqW& }AJ^%5lޫ7QZ,bʛ2 zM-v>dDiui3Xf񟠹߯/31=.$N}4= 6|NsQ.]4-5-H)hAxXiRDy.tfr=gS'Tjy=$gdO; s駉LvhCMh}X+wr.Dy %+؄`Mk ?>IY[eKjd]1@@ZnpMJ\ɜf`}먽L X*s6^4('+iF0VL@hjZhQT5ž#49d0 3V,&y-')9YZ%sURle\n3 l̮uyaWgZgl#;5H(~ BR<j.nVՋvne-H@#e|Q8~_ &.ڻdܙ{UL=_G˿tQ\8zC=ꮖVM0+];[<}I ~M9UUF$ݘrҀRzHVe'iJJ9#̃} 6L&@ڧ?(g@l₭ȋ8'6;Fy/k$Ad0KJ&?^BTHjb~qhnt_~-g:nViIFۼ"Q5N$ͬ#`\Mןޝs0Ɗ`ܠFkbkzF+ǭr(5/|x3L\=Y!qH]Gqpm%q %):yq*‡%$6b%=y_wՓ#%-Yp㘱@W$'bJ4."(n6|CvKkK}k%4?i{4@yrr'.c9Ċ&/7nrG`}4:;5_\rEs- hLit.y }>.ITQ\@lzO/y%T} y*y+)'xkepjBP±j%Z12 QJ;N=EpfJAI ,o=vVSs*>{R:y-o_yg7T9o"}F VקE($_bMq*󜮙iCcgz<\e x{B^S`;SU%cfHrZ"c > GQ7 v, 2S@r7Fk'@ .M;,9 dޞW3FS/H[/y[h[ "c͓Z\D+7CJMҿ ǩۛየpVf}Dsj/HetTkrBVϿy+w աU$x8h'X9v&=S~ g qW~,ސDWkʥnIx z%jhL)\j9}i@dl<7g:^|Pv'7c*o/*f*ҥ,7PW?)wݜu$乴΍4Xؓ$İSS'u4f`CXxzN0c|`?Sm&HfH@xCK^߭,hlFSKUG;Ѧve}Gms@]#4Crc)t%ftrI>O=c>G50O-re{t2Y<RwP6 .j0!b=nAK 8wY@!Jm]E7d6c(vv<5)`Rd=YOS6)@(+őK44*+w`HӊUO%3/NS5QxCer u6z'k<;a_8%tǝ BJG9;q{UU)L=֮ٷy/ I~.+ KV5PꈩӶU x!ӇXO*1|섆Ljst5"bp ~!WCMX5-RuWŕ -Z:B]fx9P3cX";Wk~c{J[ ń}oJNn^j SwZɨCu2Z=P'"7z)o^!q,B+QVK_q .SA v31>uSfs4u@Jݠ0@L /qߐ_58k^CeRo:[\(CQ| /Ĺ6A9gDeܜ*@ԉr >糦)3հ(􁵢.ȳ4< 8;zCS-72%<$0{\ڗW7 6|?ȊEv/ |NU!Qoܑ rWjY/Qχ{#dqS_W\%։->,ҦaOMCLdG ^4IO'5kpu1NC Bg5Uo&!g (c?#O謹tkPhi뮘pd8޲&0!R@ ⾻| ,W,l f"hPi弳|2/16$n@sV ^k6=_BHP3Օ<=ovL򝣗ij:]r"),i& 맨#:Ӂ 5#$?1_NA=\3^\#d.:K.ҁϛ<3R *s Ua+ӖA؅䝱&yAڂ_m̈P* Gfń 0g-|Y)&ɅlD eQV'|X4@Y u0i x)/qHV(d噰UzQpt=??Q5 Y@;q:~kV>Y@Fle.#|T-{c+pqc׵*) ԯvSKD?ă3F֑¶Š 8զ厦cKVBH `ԎBg+nJU @<#d!O;(UOx3*8ru ٥׫>GP;% #P=>Kt@k{if)PIZj~Zu@ZzԐe'rf:62!Vi  KP^]qJy:1=U'g1w[xQZ|\hs3&YDWwJ"um fNY45]Z8!, xfaSS},thփ!,G$! xh Siɉjsa[A\ b0Q@ef˲,_O=;e}3sd4@ ŎAo6^]{"@}2 ş̑\C'8$km@wPw-D@,7S9hɝ0w!2ax*@:mm`hf2 QH82_UUl>n[ gS%f-A ]BZB'pxi`I 6@8m'6XbA SO-)u/ת-YI7O9@NfU!@&#|Cz[OJwPcm1We:Zh=HLAd}!W#[3aC FȨ7` |EX#+1#askr㬴nѬ~ToXd9X7onJƇh4UYF,XM k7ax(Z QHoXmSg̚'=>0:8ډ'{p^0Y ?_FNRO$/qCȺm3Rwft 8$̮"q/I7I{.à}CΟuNqI섍ߞ9 9mﺐN$_)0t\4Կ- w) F (cX-./,rH&lhpŠsE*l;2&9<"-E4 D.;1ӵqhes<υ.ׯ3Q6Q%)l\atdY-+Y:FRUX5 j+wӭE||"]pu(6y C>V9Q%j %i,EIRgE%ًcjVC9]f N,ǂZP/:lBH$ )݄DF+.71jŃk$ZQڼx9?q[lf]1(3E;{ CB -K]|"2zޗl 2G_xSb& Ik* JSZUC |{lUOWo-8h`rfzǻW0000000000000000000000000000000000000000000000000000000000000000 0000000000000000000000000000000000000000000000000000000000000000 0000000000000000000000000000000000000000000000000000000000000000 0000000000000000000000000000000000000000000000000000000000000000 0000000000000000000000000000000000000000000000000000000000000000 0000000000000000000000000000000000000000000000000000000000000000 0000000000000000000000000000000000000000000000000000000000000000 cleartomark endstream endobj 9 0 obj <> endobj 804 0 obj <> endobj 805 0 obj <>stream %!PS-AdobeFont-1.0 %%This font is a conversion from Helvetica-Condensed with the following copyright notice: %Copyright (c) 1985, 1987, 1991, 1993 Adobe Systems Incorporated. All Rights Reserved.Helvetica is a trademark of Linotype-Hell AG and/or its subsidiaries. 11 dict begin /FontName /Helvetica-Condensed def /FontType 1 def /FontBBox {-166 -239 1062 812} readonly def /FontMatrix [0.001 0 0 0.001 0 0] readonly def /PaintType 0 def /FontInfo 8 dict dup begin /FullName (Helvetica-Condensed) readonly def /BaseFontName (Helvetica-Condensed) def /Notice (Copyright \(c\) 1985, 1987, 1991, 1993 Adobe Systems Incorporated. All Rights Reserved.Helvetica is a trademark of Linotype-Hell AG and/or its subsidiaries.) readonly def end def /Encoding 256 array 0 1 255 {1 index exch /.notdef put} for dup 32 /space put dup 33 /exclam put dup 34 /quotedbl put dup 35 /numbersign put dup 36 /dollar put dup 37 /percent put dup 38 /ampersand put dup 39 /quoteright put dup 40 /parenleft put dup 41 /parenright put dup 42 /asterisk put dup 43 /plus put dup 44 /comma put dup 45 /hyphen put dup 46 /period put dup 47 /slash put dup 48 /zero put dup 49 /one put dup 50 /two put dup 51 /three put dup 52 /four put dup 53 /five put dup 54 /six put dup 55 /seven put dup 56 /eight put dup 57 /nine put dup 58 /colon put dup 59 /semicolon put dup 60 /less put dup 61 /equal put dup 62 /greater put dup 63 /question put dup 64 /at put dup 65 /A put dup 66 /B put dup 67 /C put dup 68 /D put dup 69 /E put dup 70 /F put dup 71 /G put dup 72 /H put dup 73 /I put dup 74 /J put dup 75 /K put dup 76 /L put dup 77 /M put dup 78 /N put dup 79 /O put dup 80 /P put dup 81 /Q put dup 82 /R put dup 83 /S put dup 84 /T put dup 85 /U put dup 86 /V put dup 87 /W put dup 88 /X put dup 89 /Y put dup 90 /Z put dup 91 /bracketleft put dup 92 /backslash put dup 93 /bracketright put dup 94 /asciicircum put dup 95 /underscore put dup 96 /quoteleft put dup 97 /a put dup 98 /b put dup 99 /c put dup 100 /d put dup 101 /e put dup 102 /f put dup 103 /g put dup 104 /h put dup 105 /i put dup 106 /j put dup 107 /k put dup 108 /l put dup 109 /m put dup 110 /n put dup 111 /o put dup 112 /p put dup 113 /q put dup 114 /r put dup 115 /s put dup 116 /t put dup 117 /u put dup 118 /v put dup 119 /w put dup 120 /x put dup 121 /y put dup 122 /z put dup 123 /braceleft put dup 124 /bar put dup 125 /braceright put dup 126 /asciitilde put dup 161 /exclamdown put dup 162 /cent put dup 163 /sterling put dup 164 /fraction put dup 165 /yen put dup 166 /florin put dup 167 /section put dup 168 /currency put dup 169 /quotesingle put dup 170 /quotedblleft put dup 171 /guillemotleft put dup 172 /guilsinglleft put dup 173 /guilsinglright put dup 174 /fi put dup 175 /fl put dup 177 /endash put dup 178 /dagger put dup 179 /daggerdbl put dup 180 /periodcentered put dup 182 /paragraph put dup 183 /bullet put dup 184 /quotesinglbase put dup 185 /quotedblbase put dup 186 /quotedblright put dup 187 /guillemotright put dup 188 /ellipsis put dup 189 /perthousand put dup 191 /questiondown put dup 193 /grave put dup 194 /acute put dup 195 /circumflex put dup 196 /tilde put dup 197 /macron put dup 198 /breve put dup 199 /dotaccent put dup 200 /dieresis put dup 202 /ring put dup 203 /cedilla put dup 205 /hungarumlaut put dup 206 /ogonek put dup 207 /caron put dup 208 /emdash put dup 225 /AE put dup 227 /ordfeminine put dup 232 /Lslash put dup 233 /Oslash put dup 234 /OE put dup 235 /ordmasculine put dup 241 /ae put dup 245 /dotlessi put dup 248 /lslash put dup 249 /oslash put dup 250 /oe put dup 251 /germandbls put readonly def currentdict end currentfile eexec M#1H5 J6o \&rtS(#v\0\޹V7Fe༙OYx5-cY9^%Y6 (efIOldN"wȰ;)UƽoFg/rvV$JS8_oc@  o9-eGJp}[Do]mN=4*{ܯq=eU^t6¤)w Rfxpc @X$UČc@:p:20eַl&^ Zњ s `? q m2ӿ&W۟4Cga}e!ic#Cn^* +j^"&&% ̓'7@_}&KxAzX#,…;'wZ`m4qfF4٦;Q+#ݲ!>c/ft,lͣgl 5C6 i#MNQ8|-ZCڻ BW=-ٙ&:M#qr)f^#U$.\NONQv^*rei=qGu ­YynH7K#P*ç.s|uPRY oFz`*س=avظx8_rXOEv.| ;)\0dǸD&E @7Iq|CcO'o1U(,%XE-ĆB:iAz]C~e+l#TbA(Q~|aHVar]֊j[?|$:3+r'MvrSE+zܪ?1QMu3-1tlGpQ xF SpGRӯ:;Yx#,&0FK7"&'Y$QxήmsE @x("v, jbX3X]%~U}kμ)lP2ƿMʪolzoVD-x=%<$ f < JӺ8VvhBZn&N` X﻽N\:m6|b utZoJ .O<AC9||Dݾ1i &P XG {́ a=01V/Κc~$_@ 0diq>N=ScG+bqm껳 k ^Az-z3pϟ`Cc&`K{sy!IӔh/rN1nF*Bѣi갟/r߬{Ԗ?y  6MR q^؂b!%s$>ABjjY]aa9Lad$ 5-a9o:7 #e5K㓋m&-rshgc;Dfd9G|d ;i+0JeّI]V"~BZ DMV 9@P) K ,Z(;~19{;3n5ǝmv/-T\c4OƬԺ>gp| lB55̖L{bM&\AXk`FXV1=q?-MFŢ~VqK {]6dfԵ3^},? 锔ܯpPFſ>t^ijNl㦰H 0||qFT#a]ՆXKf[2͢d x~uâ6lfzB{xE% )Ǽ]b - 8!<ًs x b3ȰQP ʸf5z 5-/- vY٢,qOώʻhid~K?mf&Ht&-Jeڎu!>,k7V bAf_$U,QEKS,ЕkY6 ҆.giP|DFp; Q=+--֬0,L0_ ;0iWp1\U.E y$c{KutrsE|1_dg5%Eu#.B4+rf˕a2uoT ʥFljJ{gPil]8{\2HFtaL S ȧ)PqF_Bɴ4s3TRW-Q,:2Џ>_*eR)1yb8k[QۅezݴKʏyPfROw*jʻPjA[]_ O 5XNc 1w_*BM!CgKɢӈRx\8>J\=R? !887?)wRcL(N~u{iI) D}WjQg=lofx䡄~I${LaP@6G~cFMae28YssE[jz~aGE:w'mF5`7wt/aR{WM&xm BRD7^kËBBt!kVDR@t"n2E(,,k"aWI{!3fj!uhxs Cw6)[g>]qqF5j1\oZ $q2qƶyDC,%mϰ\?(T̗,k97gܓ:tŬ .Gl˨/Чzo nՆ&UJe"OM3 ?GƳٗ_t|e1ꌺt!Ap-\K #L}K6=3ژ/vkڂ.ֆ*ټ? I(zs2# VmC!o!I3c㽗W@_ _cn_1_63TE9 6l0$C*x7'Ĕ/a:wS+ȥ_<0o$BҢ95HXX7QN7a@AX"}lB6C/M0_چPewFώ-J|1Lm03}h|Xs&>f=k1QӪ}=U{rE`i/W6 Wh^m{~>ɳ8?Kf.ޗJ现ʷ=6ԴܳyP< \iߞe9 se6?A\_3}E4:'av:z74A{w>RMlh#auh.B-@+iiڽ6 Foi<_i1iWZrEv M I.ۃPPwdƑ2bRnS]1h6R)KԤ*P8qZI[\j 5,O We RCanF K%QW:'xdU&ȘXBA)l hk!S{@D!͸zД* )pS[E07m[wa:O!f,ORڕV\ L=9qվbvn\gpQtJZVY:tSy]B/H@ -L,6сlvRl["" ֱ?3Q+I".ĚT"cJNrCEȮҧ_F" +YŨHXbT['VFB+LeS&a,rؤ_=2RLrRZ}ݒUM[wA0 *gٿ GwXa`p{_.aڋ.4#}% Oo͛u31ٗ!!_sykMM+$2Ϥ<30. dީ"*+PLBYqruZ jPw,e`f6hY32Thd[JUݥGuzh}1;4Y  K٣ʾ:{R<*Wq~YҗW"@&%.*AroKP\qtC5K&,p s0E(@ado WgN'ӗAIYnwJs++#Nb*AD{%NNKR_ ۽9C3q$w )FRp(/Rᡫ#hO50~=Jb(L3ҹ3( rtO1<͂2s{WГ5&L7%&B zP3/S[x16Y2b//wPm\Tg %8ѥ@<PgB]Ҥ`Kh]\]ר,~)NI->n@Kf0 p #rf"o섴u JuL0LRʤ4͒BTF”rV@p:!n? 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B})>= GF\_ u$El~$-r`߳DTf{37410/.-ؿ<vv"-XGV+ljm@u?_۞8gN1įs+φ GǴ+?_hY) q`4|Q$/Rl (fTZR>05ĎY%ʙ>v#>رVڥ`tw΃v(?G苴DZݧ4qD[4;M8ߣqNcR8!}0Έ`E52[ 4dF21;[e!ˤ> J!4lRzE%Rgo&a2c!u=}bߣ<<v++ߌszN[_XK&3Cl5F62'wﯫ+"9!B Хݶ1}qc ZUkW\EHty/>-*)\TBK5! >q19 ǘcqv* MjKJc`.+R>kFJ"ЋFXPTbf8 l&XhPP:d+hNּٮ-([^.AdD4P_|=p~sX^Mp6CUPŌMp_ kWFM5ɼc tZK$hH/b_ PZF#r̳O w!$Jotl5ə;aBZ -q5ke`;Gb5!&Q_1'-ZηA)|cՃENkFE/q1kNw.԰s X 6 kzsB؞]ECT+jЖ"B{13'8f%1xDJ4s }j%pOYsQ3ye΋xr_0K:-&O7=Dyabr&: wUԧlq> g7x:#F~3F#UHAE?b26$iJLc⦒Ⱥ"~F@y_ouAcҕ=$feEqH}eFQ2]LCiK'g+ D_`G^7Fg3V=D|t_a4B9DZMhny|tlklju^!OhaV^>| ~djQzY2:d@.*3NXֿMA,M0ʉ3+R̄%KK$T\̟6z^eMH-:eeDsyZ:!eMv}đE|o/9U1na忉rQ*-B'G\Ybc|m\ TAZG5'ss ڣx@xYIM<\;9d,iIV;9!6T %N.tR3сڛ_tIkdQ[H66kMTwZW&k♲/,Íf<|zu;)>J4}sX b!y)*.Og_?b䓯ū,ӼmxH<]y{L\cz29|VuϘy9Z/6)4$=ol JW4 }:jF='yr;},1=H0#z ;K=]ϖ;V+Z O1\eͮp[!)!< C&E%4;ͮ pI6ݮ@϶hfZ"&9@_n"V ĕ` e|IAm,AU|vb>0T VxpݱgI~lM #}72l9#$<ȈB[^0&{&og_'dBμ%t;۟͋Zql"N_?. /Mc9%!?Mv ':A\+#3*||65؉VZ))t:U~돐(V 'OxH F֦`?¿ƅ *cL Pp|+蒤MF/>mB,C U +s{н^/o{~-{_Lg20Lf*i]Y\\_#p3{kGZ_STw3747 (뻖{)O9ّhBh32yT}P1(qj;$cKգY<)#x{?Gg]Bt=\ Maw%~T/ $7ZR "<&qvOڔ%EjԿq, )mϳg,]턘Oā^UϤtZv4$Jm zl4Is ΅u)tz&+\+q sPP*5!˄%SXY{?g@$a!  %?j_0=hX8~ g5XM XYPd;N|}Gh FynlT uo9Myg=N^,l?xiT3؊7$˘hV]PfF~sX/3T昶}\o3'<-o@ít1aZh)I̵&gBkOL;\iRiư@.%kP1YGac@[>\TU^zo#&ڢ4"Qg4;~0sF TH.]X1d ;/MQJw\z!Ex}%P@8,A+^^FL]Y %V3iRaN0ZL4g1W@h~ᤝkCa4Yy>bƼrN5"KyÀvu5”m( Ƅ! ԡa)Yp5̓÷%.߰Fz2?К@DrȌ _!B䕄sgA qRˇ\!1e>B.=K_圶V^Y:u]/WI!S\s#q%? 3ɒzG/= %Y_b'%vϬ_/M Wz_1F? 0ěA3ǀaepfq~u+RRPavQO;Y</& :v6"x3rf1=?'lig{cpF0Je! ّ8Epsǯ9-+By.'?'Ч*n\r.gGZNrg΂!QIυBFZ;L集n7Cv!׸*SslhPQG: 5i6i_,xV8$zHDžO97mZXw˅h|(wxR.A( ,kr@h`>$ ?Yr L! iꮝJLm%*,~O^7>R@Di)ݗ3[w-!Hu0eUa1۪: Nq퍆y8 ;&elS7-Rԝ(XBbDSt~`۠~&ZaxǍBt9>&;a-i{,]go!K1=b^e26p٠ T*h) oQVΣIhOèF&ġH2&ٴkΰZ%rGF.ߨlJ!?PE73]_Hނpd ?h?^{Pd'@rf{jwx9"Y?K5:k&P+ea0&AŊc' )xN0000000000000000000000000000000000000000000000000000000000000000 0000000000000000000000000000000000000000000000000000000000000000 0000000000000000000000000000000000000000000000000000000000000000 0000000000000000000000000000000000000000000000000000000000000000 0000000000000000000000000000000000000000000000000000000000000000 0000000000000000000000000000000000000000000000000000000000000000 0000000000000000000000000000000000000000000000000000000000000000 cleartomark endstream endobj 772 0 obj <> endobj 806 0 obj <> endobj 807 0 obj <>stream %!PS-AdobeFont-1.0 %%This font is a conversion from Helvetica-Condensed-Oblique with the following copyright notice: %Copyright (c) 1985, 1987, 1991, 1993 Adobe Systems Incorporated. All Rights Reserved.Helvetica is a trademark of Linotype-Hell AG and/or its subsidiaries. 11 dict begin /FontName /Helvetica-Condensed-Oblique def /FontType 1 def /FontBBox {-166 -239 1125 812} readonly def /FontMatrix [0.001 0 0 0.001 0 0] readonly def /PaintType 0 def /FontInfo 8 dict dup begin /FullName (Helvetica-Condensed-Oblique) readonly def /BaseFontName (Helvetica-Condensed-Oblique) def /Notice (Copyright \(c\) 1985, 1987, 1991, 1993 Adobe Systems Incorporated. All Rights Reserved.Helvetica is a trademark of Linotype-Hell AG and/or its subsidiaries.) readonly def end def /Encoding 256 array 0 1 255 {1 index exch /.notdef put} for dup 32 /space put dup 33 /exclam put dup 34 /quotedbl put dup 35 /numbersign put dup 36 /dollar put dup 37 /percent put dup 38 /ampersand put dup 39 /quoteright put dup 40 /parenleft put dup 41 /parenright put dup 42 /asterisk put dup 43 /plus put dup 44 /comma put dup 45 /hyphen put dup 46 /period put dup 47 /slash put dup 48 /zero put dup 49 /one put dup 50 /two put dup 51 /three put dup 52 /four put dup 53 /five put dup 54 /six put dup 55 /seven put dup 56 /eight put dup 57 /nine put dup 58 /colon put dup 59 /semicolon put dup 60 /less put dup 61 /equal put dup 62 /greater put dup 63 /question put dup 64 /at put dup 65 /A put dup 66 /B put dup 67 /C put dup 68 /D put dup 69 /E put dup 70 /F put dup 71 /G put dup 72 /H put dup 73 /I put dup 74 /J put dup 75 /K put dup 76 /L put dup 77 /M put dup 78 /N put dup 79 /O put dup 80 /P put dup 81 /Q put dup 82 /R put dup 83 /S put dup 84 /T put dup 85 /U put dup 86 /V put dup 87 /W put dup 88 /X put dup 89 /Y put dup 90 /Z put dup 91 /bracketleft put dup 92 /backslash put dup 93 /bracketright put dup 94 /asciicircum put dup 95 /underscore put dup 96 /quoteleft put dup 97 /a put dup 98 /b put dup 99 /c put dup 100 /d put dup 101 /e put dup 102 /f put dup 103 /g put dup 104 /h put dup 105 /i put dup 106 /j put dup 107 /k put dup 108 /l put dup 109 /m put dup 110 /n put dup 111 /o put dup 112 /p put dup 113 /q put dup 114 /r put dup 115 /s put dup 116 /t put dup 117 /u put dup 118 /v put dup 119 /w put dup 120 /x put dup 121 /y put dup 122 /z put dup 123 /braceleft put dup 124 /bar put dup 125 /braceright put dup 126 /asciitilde put dup 161 /exclamdown put dup 162 /cent put dup 163 /sterling put dup 164 /fraction put dup 165 /yen put dup 166 /florin put dup 167 /section put dup 168 /currency put dup 169 /quotesingle put dup 170 /quotedblleft put dup 171 /guillemotleft put dup 172 /guilsinglleft put dup 173 /guilsinglright put dup 174 /fi put dup 175 /fl put dup 177 /endash put dup 178 /dagger put dup 179 /daggerdbl put dup 180 /periodcentered put dup 182 /paragraph put dup 183 /bullet put dup 184 /quotesinglbase put dup 185 /quotedblbase put dup 186 /quotedblright put dup 187 /guillemotright put dup 188 /ellipsis put dup 189 /perthousand put dup 191 /questiondown put dup 193 /grave put dup 194 /acute put dup 195 /circumflex put dup 196 /tilde put dup 197 /macron put dup 198 /breve put dup 199 /dotaccent put dup 200 /dieresis put dup 202 /ring put dup 203 /cedilla put dup 205 /hungarumlaut put dup 206 /ogonek put dup 207 /caron put dup 208 /emdash put dup 225 /AE put dup 227 /ordfeminine put dup 232 /Lslash put dup 233 /Oslash put dup 234 /OE put dup 235 /ordmasculine put dup 241 /ae put dup 245 /dotlessi put dup 248 /lslash put dup 249 /oslash put dup 250 /oe put dup 251 /germandbls put readonly def currentdict end currentfile eexec M#1H5 J6o \&rtS(#v\0\޹V7Fe༙OYx5-cY9^%Y6 (efIOldN"wȰ;)UƽoFg/rvV$JS8_oc@  o9-eGJp}[Do]mN=4*{ܯq=eU^t6¤)w Rfxpc @X$UČc@:p:20eַl&^ Zњ s `? K֖mo7kvQث.-ߘΕfՁ:C^r# B ͉+|sCM{Ⱥ"ZmZ(sB6Wݫ"䡘< W) :\1Hƾ4TOD4#z3sӇ3Xh1bؒUW8[!M;?/4+{K1ECZ/#h,7&32984+ʭLU! g YϢvPO;"eg`'w@ACq$3*D*+b`gH E̞ =RŸz`۔keOʋv :0='GP+D!2dfa"1b%禡fVXhՍs829Z/r)ܑidτ|y0䏏+5-Mk1"W_U8򣨻a%]YdFTGc8sA|b$F[@\3!y~ a8\㹵c: 6ۖOsK vqAD󲻋E*Q.IM-d#턉Mj\0܋\yl㧛0֊55ț>0!,JHWĴzt T?٦6jfp $0SIb}Јa#[ƷJ&e`D([Vt \4S^one|[)A&eb"y= ]g#?LJǍA\EiG~[kCBҩiFV^U!lhA)jB[+r[|´c(.^T<kf`ŒN6Uо>)zU/"ֆjo,>Lb;Tlx񶖉pǂxbB/=1}[hF_4EӇm>\&zU/{|?_J$#{Oܗء*>5&Z& T*+9")IUG6u؎M,\Fi.'b$H h F2QL°G Tt ]~hv]$>c*zIO/K5ȠH 9&Fo'MTbd2%d#Ф"etOWjKan٘*.GCg6aݠ^X@,T @2J3-5׭*Ck \" %a֎#C^ohvxVN?Y\~뀫6wzB5òG9ev/pR2>jxb§b8 $b sa&ݙm{DO 5@Ѽ/"fiL6#Z$5 O5V lªv,‹Ť2Zڎ˘Uն9X O}DC^VJo nݞ:?G5Ouqj!ކFk{"|_t:,$e>T͔xщ S·k^";$f[g >~XMc \;KȒ;\F0NiwP_4~0*:hawzqh ұ[J>U~[^8:"Gਃ^0|"I{ӱS4^l\k첉rgHPɕ7[-xɂ4[NyN7q2Fuڤ7(e[kҙ`͆FAl=(ƽ\]L64XD>JAz9]S.hD E0ٺ`C)bn=P-ho lkU}dU>>4s زZIZn)#R7Nڤu~=kEFPL2N2wv|dKrWI^k{)&$(J~m &i3LLywbw"7pS ͗k;v{s->L@'*a?f~+J a|2L}2ͱ 3zS]b12oEV<%>Y s}vtH#n;JBے,bp ͑ANe# ml!(A"')IXgHM:Bhw dnw}Wf Om}aw3T$?Vcj\waFx-$:JP$R0cza \9<wҺU)Pˏҹf1ZBk(hUb`w U;ٻʬ o* ~'uXNUzi&%W\=:HvIyJqPm'8LV Yɲ?+bӤtr)Ip:sM V14~s~˖C/¢Ztgw҄ "@ "u>MQ#LJWQx8 {0ʡHwM{v.VO@ZH+X5ɞF:U"q8@'jhcBЍj˂=a(x Y"4 ޾VZ2E5wۯv mٮieoÐ4c:7ax_9|H>ߣ@n*ڻW԰;;ܒ$ոN.@!oQ ζ قϳ? 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